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Microbiology

D-Index
65
Citations
15538
World Ranking
2498
National Ranking
215

Overview

Greg J. Towers is affiliated with University College London in the United Kingdom. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology, with a focus on various subfields including Infectious Diseases, Molecular Biology, Immunology, Virology, and Oncology.

The main research topics addressed by Towers include interferon and immune responses, HIV research and treatment, SARS-CoV-2 and COVID-19 research, COVID-19 clinical research studies, vaccines and immunoinformatics approaches, mosquito-borne diseases and control, and viral infections and outbreaks research.

Towers has published extensively in several peer-reviewed journals and preprint repositories. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Microbiology
  • eLife
  • The EMBO Journal

Recent papers authored or co-authored by Towers include:

  • SARS-CoV-2 variant biology: immune escape, transmission and fitness, 2023, Nature Reviews Microbiology
  • Evolution of enhanced innate immune evasion by SARS-CoV-2, 2021, Nature
  • SARS-CoV-2 sensing by RIG-I and MDA5 links epithelial infection to macrophage inflammation, 2021, The EMBO Journal
  • Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • SARS-CoV-2 variants evolve convergent strategies to remodel the host response, 2023, Cell

Collaborations form a significant component of Towers's research output, with frequent co-authors including:

  • Lucy Thorne
  • Clare Jolly
  • Ann-Kathrin Reuschl
  • Lorena Zuliani-Alvarez
  • Matthew V. X. Whelan

The combination of their research areas and publication records indicates sustained involvement in infectious disease biology and immune response mechanisms, with particular attention to viral pathogens such as HIV and SARS-CoV-2.

Best Publications

  • SARS-CoV-2 variant biology: immune escape, transmission and fitness

    Unknown

  • Positional cloning of the mouse retrovirus restriction gene Fv1

    Steve Best;Steve Best;Paul Le Tissier;Greg Towers;Jonathan P. Stoye

  • Evolution of enhanced innate immune evasion by SARS-CoV-2

    Unknown

  • HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.

    Torsten Schaller;Karen E. Ocwieja;Jane Rasaiyaah;Amanda J. Price

  • Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

    Donna L. Mallery;William A. McEwan;Susanna R. Bidgood;Greg J. Towers

  • HIV-1 evades innate immune recognition through specific cofactor recruitment

    Jane Rasaiyaah;Choon Ping Tan;Adam J. Fletcher;Amanda J. Price

  • Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors.

    Greg J Towers;Theodora Hatziioannou;Simone Cowan;Stephen P Goff

  • The human and African green monkey TRIM5α genes encode Ref1 and Lv1 retroviral restriction factor activities

    Zuzana Keckesova;Laura M. J. Ylinen;Greg J. Towers

  • Restriction of lentivirus in monkeys

    Caroline Besnier;Yasuhiro Takeuchi;Greg Towers

  • A conserved mechanism of retrovirus restriction in mammals

    Greg Towers;Michael Bock;Samia Martin;Yasuhiro Takeuchi

  • Restriction of multiple divergent retroviruses by Lv1 and Ref1.

    Theodora Hatziioannou;Simone Cowan;Stephen P. Goff;Paul D. Bieniasz

  • The control of viral infection by tripartite motif proteins and cyclophilin A

    Greg J Towers

  • TRIM22 Inhibits Influenza A Virus Infection by Targeting the Viral Nucleoprotein for Degradation

    Andrea Di Pietro;Anna Kajaste-Rudnitski;Alexandra Oteiza;Lucia Nicora

  • CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.

    Amanda J. Price;Adam J. Fletcher;Torsten Schaller;Tom Elliott

  • Independent evolution of an antiviral TRIMCyp in rhesus macaques

    Sam J. Wilson;Benjamin L. J. Webb;Laura M. J. Ylinen;Ernst Verschoor

  • HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2

    Karen E. Ocwieja;Troy L. Brady;Keshet Ronen;Alyssa Huegel

  • HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis

    David A. Jacques;William A. McEwan;Laura Hilditch;Amanda J. Price;Amanda J. Price

  • Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion.

    Ravindra K. Gupta;Stephane Hue;Torsten Schaller;Ernst J. Verschoor

  • SARS-CoV-2 sensing by RIG-I and MDA5 links epithelial infection to macrophage inflammation.

    Lucy G. Thorne;Ann Kathrin Reuschl;Lorena Zuliani-Alvarez;Matthew V.X. Whelan

  • Disease-associated XMRV sequences are consistent with laboratory contamination

    Stéphane Hué;Eleanor R Gray;Astrid Gall;Aris Katzourakis

  • Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration

    Ravindra K. Gupta;Petra Mlcochova;Annegret Pelchen-Matthews;Sarah J. Petit

  • Differential restriction of human immunodeficiency virus type 2 and simian immunodeficiency virus SIVmac by TRIM5alpha alleles.

    Laura M. J. Ylinen;Zuzana Keckesova;Sam J. Wilson;Srinika Ranasinghe

Frequent Co-Authors

Leo C. James
Leo C. James MRC Laboratory of Molecular Biology
Mahdad Noursadeghi
Mahdad Noursadeghi University College London
Paul Kellam
Paul Kellam Imperial College London
Philip J. R. Goulder
Philip J. R. Goulder University of Oxford
Deenan Pillay
Deenan Pillay University College London
Yasuhiro Takeuchi
Yasuhiro Takeuchi University College London
Richard A. Goldstein
Richard A. Goldstein University College London
Ralf Bartenschlager
Ralf Bartenschlager Heidelberg University
Jonathan P. Stoye
Jonathan P. Stoye The Francis Crick Institute
Paul D. Bieniasz
Paul D. Bieniasz Rockefeller University

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