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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
9737
World Ranking
13406
National Ranking
5695

Overview

Yong Xiong is affiliated with Yale University in the United States and has made contributions primarily in the fields of biochemistry, genetics, molecular biology, and medicine. Their research encompasses specialized subfields including molecular biology, infectious diseases, virology, cell biology, and immunology. The scientist's work spans several key topics such as HIV research and treatment, SARS-CoV-2 and COVID-19 research, HIV/AIDS drug development and treatment, advanced biosensing and bioanalysis techniques, bacteriophages and microbial interactions, RNA interference and gene delivery, and interferon and immune responses.

Notable recent publications by Yong Xiong include:

  • Functional landscape of SARS-CoV-2 cellular restriction, 2021, Molecular Cell
  • Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA, 2020, Molecular Cell
  • Metabolic characteristics of lactic acid bacteria and interaction with yeast isolated from light-flavor Baijiu fermentation, 2022, Food Bioscience
  • Cryo-EM structure of an active central apparatus, 2022, Nature Structural & Molecular Biology
  • Sorting sub-150-nm liposomes of distinct sizes by DNA-brick-assisted centrifugation, 2021, Nature Chemistry

Yong Xiong has frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), the Journal of Biological Chemistry, Nature Structural & Molecular Biology, Fuel, and the Proceedings of the National Academy of Sciences. These journals reflect a balance between preprint dissemination and peer-reviewed research outputs.

The scientist often collaborates with various coauthors. Frequent collaborators include Chunxiang Wu, Swapnil C. Devarkar, Yingxia Hu, Qi Shen, and Therese N. Tripler, reflecting consistent partnerships in their research endeavors.

Best Publications

  • Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families.

    Anas M. Alazami;Nisha Patel;Hanan E. Shamseldin;Shamsa Anazi

  • Protein-induced photophysical changes to the amyloid indicator dye thioflavin T

    Leslie S. Wolfe;Matthew F. Calabrese;Abhinav Nath;Dorottya V. Blaho

  • Design of stable alpha-helical arrays from an idealized TPR motif.

    Ewan R.G. Main;Yong Xiong;Melanie J. Cocco;Luca D'Andrea

  • BRCA1–BARD1 promotes RAD51-mediated homologous DNA pairing

    Weixing Zhao;Justin B. Steinfeld;Fengshan Liang;Xiaoyong Chen

  • The crystal structure of yeast fatty acid synthase, a cellular machine with eight active sites working together.

    Ivan B. Lomakin;Yong Xiong;Thomas A. Steitz;Thomas A. Steitz

  • Structure of a prokaryotic virtual proton pump at 3.2 A resolution.

    Yiling Fang;Hariharan Jayaram;Tania Shane;Ludmila Kolmakova-Partensky

  • MHF1-MHF2, a Histone-Fold-Containing Protein Complex, Participates in the Fanconi Anemia Pathway via FANCM

    Thiyam Ramsing Singh;Dorina Saro;Abdullah Mahmood Ali;Xiao Feng Zheng

  • X-ray analysis of an RNA tetraplex (UGGGGU)(4) with divalent Sr(2+) ions at subatomic resolution (0.61 A).

    Junpeng Deng;Yong Xiong;Muttaiya Sundaralingam

  • Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.

    Shuai Yuan;Lei Peng;Jonathan J. Park;Yingxia Hu

  • Functional landscape of SARS-CoV-2 cellular restriction.

    Laura Martin-Sancho;Mary K. Lewinski;Lars Pache;Charlotte A. Stoneham

  • Mechanism of allosteric activation of SAMHD1 by dGTP

    Xiaoyun Ji;Ying Wu;Junpeng Yan;Jennifer Mehrens

  • Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template

    Yong Xiong;Thomas A. Steitz;Thomas A. Steitz

  • IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet–Biedl syndrome

    Mohammed A. Aldahmesh;Yuanyuan Li;Amal Alhashem;Shams Anazi

  • Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef

    Xiaofei Jia;Rajendra Singh;Rajendra Singh;Stefanie Homann;Stefanie Homann;Haitao Yang

  • Structural Insight into the Human Immunodeficiency Virus Vif SOCS Box and Its Role in Human E3 Ubiquitin Ligase Assembly

    Bradford J. Stanley;Elana S. Ehrlich;Leslie Short;Yunkai Yu

  • Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP

    Fang Li;Yong Xiong;Jimin Wang;Hyun Dae D. Cho

  • Structural basis of cellular dNTP regulation by SAMHD1.

    Xiaoyun Ji;Chenxiang Tang;Qi Zhao;Wei Wang

  • Structural Insight into HIV-1 Restriction by MxB

    Jennifer L. Fribourgh;Henry C. Nguyen;Kenneth A. Matreyek;Frances Joan D. Alvarez

  • Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1

    Xiaofei Jia;Erin Weber;Andrey Tokarev;Andrey Tokarev;Mary Lewinski;Mary Lewinski

  • Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA

    Shuai Yuan;Lei Peng;Jonathan J. Park;Yingxia Hu

Frequent Co-Authors

John C. Guatelli
John C. Guatelli University of California, San Diego
Thomas A. Steitz
Thomas A. Steitz Yale University
Patrick Sung
Patrick Sung The University of Texas Health Science Center at San Antonio
Li Wu
Li Wu University of Iowa
Fowzan S. Alkuraya
Fowzan S. Alkuraya Alfaisal University
Baek Kim
Baek Kim Emory University
Fang Li
Fang Li University of Minnesota
Jimin Wang
Jimin Wang Yale University
Ranad Shaheen
Ranad Shaheen King Faisal Specialist Hospital & Research Centre
Angela M. Gronenborn
Angela M. Gronenborn University of Pittsburgh

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