The scientist’s investigation covers issues in Cell biology, Extracellular matrix, Epithelium, Pathology and Mechanotransduction. His research integrates issues of Fibroblast, Receptor, Autocrine signalling and Cell adhesion in his study of Cell biology. His Fibroblast research incorporates elements of Hippo signaling pathway, Transforming growth factor, Transforming growth factor beta and WWTR1.
His Extracellular matrix study combines topics from a wide range of disciplines, such as Fibrosis, Matrix and Cell growth. His Epithelium study integrates concerns from other disciplines, such as In vitro, Lung injury, Respiratory system and Basement membrane. His Pathology research is multidisciplinary, incorporating elements of Cancer research and Lung.
His primary areas of study are Cell biology, Extracellular matrix, Fibroblast, Fibrosis and Pathology. Daniel J. Tschumperlin works mostly in the field of Cell biology, limiting it down to topics relating to Autocrine signalling and, in certain cases, Epidermal growth factor. His study looks at the relationship between Extracellular matrix and fields such as Matrix, as well as how they intersect with chemical problems.
While the research belongs to areas of Fibroblast, he spends his time largely on the problem of Stiffness, intersecting his research to questions surrounding Human lung. His biological study spans a wide range of topics, including Cancer research and Idiopathic pulmonary fibrosis. The concepts of his Pathology study are interwoven with issues in In vitro and Lung.
Cell biology, Fibroblast, Fibrosis, Extracellular matrix and Pathology are his primary areas of study. Daniel J. Tschumperlin has included themes like Transcription factor, Epigenetics and Dopamine in his Cell biology study. His Fibroblast study incorporates themes from Chromatin, Histone methyltransferase, Gene knockdown and TGF beta 1.
His research integrates issues of Cancer research and Idiopathic pulmonary fibrosis in his study of Fibrosis. His Extracellular matrix research includes themes of Spinal cord injury, Lesion, Matrix and Growth factor. His work on Tissue fibrosis as part of general Pathology research is frequently linked to Rarefaction, Identity and Enos, bridging the gap between disciplines.
Daniel J. Tschumperlin mainly focuses on Fibrosis, Cell biology, Fibroblast, Cytokine and Pulmonary fibrosis. Daniel J. Tschumperlin focuses mostly in the field of Fibrosis, narrowing it down to matters related to Extracellular matrix and, in some cases, Aromatic L-amino acid decarboxylase. His Mesenchymal stem cell study in the realm of Cell biology connects with subjects such as Nuclear export signal.
His study looks at the intersection of Mesenchymal stem cell and topics like Epithelium with Matrix. Daniel J. Tschumperlin combines subjects such as Epigenetic Repression, Epigenetics and Gene knockdown with his study of Fibroblast. As a member of one scientific family, he mostly works in the field of Pulmonary fibrosis, focusing on Receptor and, on occasion, Idiopathic pulmonary fibrosis, Effector, Bioinformatics and Personalized medicine.
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Cellular senescence mediates fibrotic pulmonary disease
Marissa J. Schafer;Thomas A. White;Koji Iijima;Andrew J. Haak.
Nature Communications (2017)
Universal physical responses to stretch in the living cell
Xavier Trepat;Linhong Deng;Linhong Deng;Steven S. An;Steven S. An;Daniel Navajas.
Nature (2007)
Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression.
Fei Liu;Justin D. Mih;Barry S. Shea;Alvin T. Kho;Alvin T. Kho.
Journal of Cell Biology (2010)
Unjamming and cell shape in the asthmatic airway epithelium
Jin Ah Park;Jae Hun Kim;Dapeng Bi;Jennifer A. Mitchel.
Nature Materials (2015)
Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis.
Fei Liu;David Lagares;Kyoung Moo Choi;Lauren Stopfer.
American Journal of Physiology-lung Cellular and Molecular Physiology (2015)
Deformation-induced injury of alveolar epithelial cells. Effect of frequency, duration, and amplitude.
Daniel J. Tschumperlin;Jane Oswari;And Susan S. Margulies.
American Journal of Respiratory and Critical Care Medicine (2000)
Mechanotransduction through growth-factor shedding into the extracellular space
Daniel J. Tschumperlin;Guohao Dai;Ivan V. Maly;Tadashi Kikuchi.
Nature (2004)
Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype
Robert W. Tilghman;Catharine R. Cowan;Justin D. Mih;Yulia Koryakina.
PLOS ONE (2010)
Mechanical stress is communicated between different cell types to elicit matrix remodeling
M. A. Swartz;D. J. Tschumperlin;R. D. Kamm;J. M. Drazen.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Alveolar epithelial surface area-volume relationship in isolated rat lungs.
Daniel J. Tschumperlin;Susan S. Margulies.
Journal of Applied Physiology (1999)
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