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Biology and Biochemistry

D-Index
72
Citations
19503
World Ranking
6275
National Ranking
2945

Overview

Andrew M. Tager is affiliated with Harvard University in the United States. Their research contributions span several fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology.

The scientist's work notably intersects with multiple subfields such as Cell Biology, Molecular Biology, Immunology, Nephrology, and Hepatology. Central topics in their research include Hippo pathway signaling and YAP/TAZ, Fibroblast Growth Factor Research, T-cell and B-cell Immunology, Immune Cell Function and Interaction, Liver physiology and pathology, Parathyroid Disorders and Treatments, and Genetic and Kidney Cyst Diseases.

Andrew M. Tager has published in a range of scientific journals, with frequent appearances in the following venues:

  • American Journal of Respiratory Cell and Molecular Biology
  • Science Translational Medicine
  • Journal of Clinical Investigation
  • Nature Communications
  • Frontiers in Immunology

Recent publications include these works:

  • "Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice," 2020, Science Translational Medicine
  • "Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney," 2020, Journal of Clinical Investigation
  • "Screening for YAP Inhibitors Identifies Statins as Modulators of Fibrosis," 2020, American Journal of Respiratory Cell and Molecular Biology
  • "Specialized transendothelial dendritic cells mediate thymic T-cell selection against blood-borne macromolecules," 2021, Nature Communications
  • "Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection," 2021, Frontiers in Immunology

Their frequent collaborators include the following researchers:

  • Vladimir Vrbanac
  • Lorena Pantano
  • Clemens K. Probst
  • David Lagares
  • Alan C. Mullen

Andrew M. Tager's contributions cover a broad range of interdisciplinary topics relevant to molecular and cellular biology, as well as immunology and clinical medicine, emphasizing pathways involved in fibrosis, immune cell function, and kidney-related disorders.

Best Publications

  • The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.

    Andrew M Tager;Peter LaCamera;Barry S Shea;Gabriele S Campanella

  • Chitin induces accumulation in tissue of innate immune cells associated with allergy

    Tiffany A. Reese;Hong-Erh Liang;AndrewN M. Tager;Andrew D. Luster

  • Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression.

    Fei Liu;Justin D. Mih;Barry S. Shea;Alvin T. Kho;Alvin T. Kho

  • Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis.

    Fei Liu;David Lagares;Kyoung Moo Choi;Lauren Stopfer

  • Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9

    Pankaj Kumar Mandal;Pankaj Kumar Mandal;Leonardo Manuel Ramos Ferreira;Ryan Collins;Torsten B Meissner

  • Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β

    Polakit Teekakirikul;Seda Eminaga;Okan Toka;Ronny Alcalai

  • Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues.

    Katayoon Goodarzi;Mahmoud Goodarzi;Andrew M Tager;Andrew D Luster

  • BLT1 and BLT2: the leukotriene B4 receptors

    Andrew M. Tager;Andrew D. Luster

  • Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment.

    Andrew M Tager;Shannon K Bromley;Benjamin D Medoff;Sabina A Islam

  • A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells

    Georg Stary;Andrew Olive;Aleksandar F. Radovic-Moreno;David Gondek

  • An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.

    R. Gisli Jenkins;Bethany B. Moore;Rachel C. Chambers;Oliver Eickelberg

  • Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria.

    Gabriele S. V. Campanella;Andrew M. Tager;Joseph K. El Khoury;Seddon Y. Thomas

  • HIV-infected T cells are migratory vehicles for viral dissemination

    Thomas Murooka;Maud Deruaz;Francesco Marangoni;Vladimir D. Vrbanac

  • Fibrosis—a lethal component of systemic sclerosis

    Yuen Yee Ho;David Lagares;Andrew M. Tager;Mohit Kapoor

  • Chemokine CXCL10 Promotes Atherogenesis by Modulating the Local Balance of Effector and Regulatory T Cells

    Eric A. Heller;Emerson Liu;Andrew M. Tager;Qian Yuan

  • Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis.

    Norihiko Sakai;Andrew M. Tager

  • Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice

    Diana M. Brainard;Edward Seung;Nicole Frahm;Nicole Frahm;Annaiah Cariappa

  • T-cell trafficking in asthma: lipid mediators grease the way

    Andrew D. Luster;Andrew M. Tager

  • A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis.

    Nancy D. Kim;Richard C. Chou;Edward Seung;Andrew M. Tager

  • New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses.

    Neil Ahluwalia;Barry S. Shea;Andrew M. Tager

Frequent Co-Authors

Andrew D. Luster
Andrew D. Luster Harvard University
Jerold Chun
Jerold Chun Sanford Burnham Prebys Medical Discovery Institute
Todd M. Allen
Todd M. Allen Harvard University
Robert E. Gerszten
Robert E. Gerszten Beth Israel Deaconess Medical Center
Moisés Selman
Moisés Selman National Autonomous University of Mexico
Peter Caravan
Peter Caravan Harvard University
John C. Wain
John C. Wain Harvard University
Annie Pardo
Annie Pardo National Autonomous University of Mexico
Mari Mino-Kenudson
Mari Mino-Kenudson Harvard University

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