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Genetics

D-Index
76
Citations
15159
World Ranking
1852
National Ranking
847

Overview

Gerald R. Smith is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Molecular Biology.

Their work includes more specialized study areas such as Genetics, Cell Biology, Ecology, and Plant Science. Key research topics covered in their publications include DNA Repair Mechanisms, Bacterial Genetics and Biotechnology, CRISPR and Genetic Engineering, Genomics and Chromatin Dynamics, Microtubule and Mitosis Dynamics, Fungal and Yeast Genetics Research, and Bacteriophages and Microbial Interactions.

Gerald R. Smith has contributed scholarly articles to various scientific journals, with publication frequency concentrated in several venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Genetics
  • Current Topics in Developmental Biology
  • Journal of Cell Science

Frequent co-authors collaborating with Gerald R. Smith include Susan K. Amundsen, Yu-Chien Chuang, Andrew F. Taylor, Randy W. Hyppa, and Mridula Nambiar.

Representative recent publications authored or co-authored by Gerald R. Smith include:

  • New Solutions to Old Problems: Molecular Mechanisms of Meiotic Crossover Control, 2020, Trends in Genetics
  • RecBCD enzyme: mechanistic insights from mutants of a complex helicase-nuclease, 2023, Microbiology and Molecular Biology Reviews
  • Host nucleases generate prespacers for primed adaptation in the E. coli type I-E CRISPR-Cas system, 2022, Science Advances
  • Chi hotspot control of RecBCD helicase-nuclease by long-range intramolecular signaling, 2020, Scientific Reports
  • Meiotic chromosome organization and its role in recombination and cancer, 2022, Current Topics in Developmental Biology

Best Publications

  • Structure of chi hotspots of generalized recombination

    Gerald R. Smith;Sam Martin Kunes;Dennis W. Schultz;Andrew Taylor

  • recD: the gene for an essential third subunit of exonuclease V.

    Susan K. Amundsen;Andrew F. Taylor;Abdul M. Chaudhury;Gerald R. Smith

  • Unwinding and rewinding of DNA by the RecBC enzyme

    Andrew Taylor;Gerald R. Smith

  • BLM ortholog, Sgs1, prevents aberrant crossing-over by suppressing formation of multichromatid joint molecules.

    Steve D. Oh;Jessica P. Lao;Patty Yi Hwa Hwang;Andrew F. Taylor

  • RecBCD enzyme is a DNA helicase with fast and slow motors of opposite polarity

    Andrew F. Taylor;Gerald R. Smith

  • A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction

    Philippe Szankasi;Gerald R. Smith

  • Chi-dependent DNA strand cleavage by RecBC enzyme

    Alfred S. Ponticelli;Dennis W. Schultz;Andrew F. Taylor;Gerald R. Smith

  • A new class of Escherichia coli recBC mutants: implications for the role of RecBC enzyme in homologous recombination

    Abdul M. Chaudhury;Gerald R. Smith

  • RecBC enzyme nicking at chi sites during DNA unwinding: Location and orientation-dependence of the cutting

    Andrew F. Taylor;Dennis W. Schultz;Alfred S. Ponticelli;Gerald R. Smith

  • Conjugational recombination in E. coli: myths and mechanisms.

    Gerald R. Smith

  • Meiotic DNA breaks associated with recombination in S. pombe.

    Marcella D Cervantes;Joseph A Farah;Gerald R Smith

  • Modification of bacterial artificial chromosomes through Chi-stimulated homologous recombination and its application in zebrafish transgenesis

    Jason R. Jessen;Anming Meng;Ramsay J. McFarlane;Barry H. Paw

  • Substrate specificity of the DNA unwinding activity of the RecBC enzyme of Escherichia coli.

    Andrew F. Taylor;Gerald R. Smith

  • Single Holliday junctions are intermediates of meiotic recombination.

    Gareth A. Cromie;Randy W. Hyppa;Andrew F. Taylor;Kseniya Zakharyevich

  • How RecBCD Enzyme and Chi Promote DNA Break Repair and Recombination: a Molecular Biologist's View

    Gerald R. Smith

  • Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe.

    N Kon;M D Krawchuk;B G Warren;G R Smith

  • DNA supercoiling: another level for regulating gene expression.

    Gerald R. Smith

  • RecQ Helicase, Sgs1, and XPF Family Endonuclease, Mus81-Mms4, Resolve Aberrant Joint Molecules during Meiotic Recombination

    Steve D. Oh;Jessica P. Lao;Andrew F. Taylor;Gerald R. Smith

  • Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion.

    Gerald R Smith;Michael N Boddy;Paul Shanahan;Paul Russell

  • Homologous recombination in E. coli: multiple pathways for multiple reasons.

    Gerald R. Smith

Frequent Co-Authors

Michael D. Cameron
Michael D. Cameron Scripps Research Institute
Karl Mechtler
Karl Mechtler Research Institute of Molecular Pathology
Andy F. S. Taylor
Andy F. S. Taylor University of Aberdeen
Harmit S. Malik
Harmit S. Malik Fred Hutchinson Cancer Research Center
Scott Keeney
Scott Keeney Memorial Sloan Kettering Cancer Center
Kunihiro Ohta
Kunihiro Ohta University of Tokyo
Sergio Moreno
Sergio Moreno University of Salamanca
Nina R. Salama
Nina R. Salama Fred Hutchinson Cancer Research Center
Jürg Bähler
Jürg Bähler University College London
Nancy Kleckner
Nancy Kleckner Harvard University

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