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Genetics

D-Index
42
Citations
9714
World Ranking
4308
National Ranking
1860

Research.com Recognitions

  • 2016 - Fellow of the American Academy of Arts and Sciences
  • 2002 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Michael Lichten is affiliated with the National Institutes of Health in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Cell Biology, and Materials Chemistry as subfields.

Their work extensively covers topics including DNA Repair Mechanisms, Fungal and yeast genetics research, Photosynthetic Processes and Mechanisms, CRISPR and Genetic Engineering, Microtubule and mitosis dynamics, Genomics and Chromatin Dynamics, and Enzyme Structure and Function.

Michael Lichten has published multiple papers across several venues. Notable recent publications include:

  • "Repeated strand invasion and extensive branch migration are hallmarks of meiotic recombination," 2021, Molecular Cell
  • "Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase," 2022, PLoS Genetics
  • "Turning coldspots into hotspots: targeted recruitment of axis protein Hop1 stimulates meiotic recombination in Saccharomyces cerevisiae," 2022, Genetics
  • "C-Terminal HA Tags Compromise Function and Exacerbate Phenotypes of Saccharomyces cerevisiae Bloom's Helicase Homolog Sgs1 SUMOylation-Associated Mutants," 2020, G3 Genes Genomes Genetics
  • "Repeated strand invasion and extensive branch migration are hallmarks of meiotic recombination," 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Michael Lichten include Jasvinder S. Ahuja, David Wheeler, Catherine S. Harvey, Andrew Ziesel, and Qixuan Weng.

The majority of their publications have appeared in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • PLoS Genetics
  • Genetics
  • G3 Genes Genomes Genetics

Michael Lichten was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2002 and was named a Fellow of the American Academy of Arts and Sciences in 2016.

Best Publications

  • Differential timing and control of noncrossover and crossover recombination during meiosis.

    Thorsten Allers;Michael Lichten

  • DNA Damage Response Pathway Uses Histone Modification to Assemble a Double-Strand Break-Specific Cohesin Domain

    Elçin Ünal;Ayelet Arbel-Eden;Ulrike Sattler;Robert Shroff

  • Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break

    Robert Shroff;Ayelet Arbel-Eden;Duane Pilch;Grzegorz Ira

  • Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae

    Jennifer L. Gerton;Joseph DeRisi;Robert Shroff;Michael Lichten

  • Meiosis-induced double-strand break sites determined by yeast chromatin structure.

    Tzu Chen Wu;Michael Lichten

  • Meiotic Recombination Hotspots

    Michael Lichten;Alastair S. H. Goldman

  • Direct coupling between meiotic DNA replication and recombination initiation.

    Valérie Borde;Alastair S. H. Goldman;Michael Lichten

  • BLM Helicase Ortholog Sgs1 Is a Central Regulator of Meiotic Recombination Intermediate Metabolism

    Arnaud De Muyt;Lea Jessop;Elizabeth Kolar;Anuradha Sourirajan

  • Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I.

    Rosemary K. Clyne;Vittorio L. Katis;Lea Jessop;Kirsten R. Benjamin

  • Mapping meiotic single-strand DNA reveals a new landscape of DNA double-strand breaks in Saccharomyces cerevisiae.

    Cyril Buhler;Valérie Borde;Michael Lichten

  • Factors That Affect the Location and Frequency of Meiosis-Induced Double-Strand Breaks in Saccharomyces Cerevisiae

    Tzu-Chen Wu;Michael Lichten

  • Mus81/Mms4 Endonuclease and Sgs1 Helicase Collaborate to Ensure Proper Recombination Intermediate Metabolism during Meiosis

    Lea Jessop;Michael Lichten

  • The location and structure of double-strand DNA breaks induced during yeast meiosis: evidence for a covalently linked DNA-protein intermediate.

    Jianhua Liu;Tzu-Chen Wu;M. Lichten

  • Meiotic Gene Conversion and Crossing Over Between Dispersed Homologous Sequences Occurs Frequently in Saccharomyces cerevisiae

    Michael Lichten;Rhona H. Borts;James E. Haber

  • Frequent and Efficient Use of the Sister Chromatid for DNA Double-Strand Break Repair during Budding Yeast Meiosis

    Tamara Goldfarb;Michael Lichten

  • Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis.

    Anuradha Sourirajan;Michael Lichten

  • Meiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1.

    Lea Jessop;Beth Rockmill;G. Shirleen Roeder;G. Shirleen Roeder;Michael Lichten

  • Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice.

    Jeremy M. Grushcow;Teresa M. Holzen;Ken J. Park;Ted Weinert

  • Association of Mre11p with Double-Strand Break Sites during Yeast Meiosis

    Valérie Borde;Waka Lin;Eugene Novikov;John H. Petrini

  • Timing of molecular events in meiosis in Saccharomyces cerevisiae: stable heteroduplex DNA is formed late in meiotic prophase.

    C Goyon;M Lichten

Frequent Co-Authors

James E. Haber
James E. Haber Brandeis University
William M. Bonner
William M. Bonner National Institutes of Health
Alain Nicolas
Alain Nicolas Institute Curie
John H.J. Petrini
John H.J. Petrini Memorial Sloan Kettering Cancer Center
Kunihiro Ohta
Kunihiro Ohta University of Tokyo
G. Shirleen Roeder
G. Shirleen Roeder Yale University
Ira Herskowitz
Ira Herskowitz University of California, San Francisco
Nancy Kleckner
Nancy Kleckner Harvard University
Joseph L. DeRisi
Joseph L. DeRisi University of California, San Francisco
Patrick O. Brown
Patrick O. Brown Stanford University

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