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Molecular Biology

D-Index
79
Citations
50937
World Ranking
1021
National Ranking
538

Overview

William M. Bonner is a researcher affiliated with the National Institutes of Health in the United States. Their work spans several interdisciplinary fields, primarily focusing on biochemistry, genetics, and molecular biology as well as immunology and microbiology.

Their research explores a variety of topics related to molecular and cellular mechanisms, including:

  • Epigenetics and DNA Methylation
  • Genomics and Chromatin Dynamics
  • Ferroptosis and cancer prognosis
  • Interferon and immune responses
  • Immune Response and Inflammation
  • NF-κB Signaling Pathways

William M. Bonner has contributed to the scientific literature with publications in several venues. These include:

  • Genes
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries

Selected recent papers authored or co-authored by Bonner are:

  • "Histone Variant H2A.J Is Enriched in Luminal Epithelial Gland Cells," published in 2021 in Genes
  • "The H2A.J histone variant contributes to Interferon-Stimulated Gene expression in senescence by its weak interaction with H1 and the derepression of repeated DNA sequences," published in 2020 in bioRxiv (Cold Spring Harbor Laboratory)
  • "Impact papers on aging in 2009," published in 2020 in UNC Libraries

Bonner frequently collaborates with other researchers, including:

  • Christophe E. Redon
  • Adèle Mangelinck
  • Régis Courbeyrette
  • Jean-Yves Thuret
  • Carl Mann

Their work covers multiple subfields of study such as molecular biology, immunology, pulmonary and respiratory medicine, and cancer research.

Best Publications

  • DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

    Emmy P. Rogakou;Duane R. Pilch;Ann H. Orr;Vessela S. Ivanova

  • Megabase chromatin domains involved in DNA double-strand breaks in vivo.

    Emmy P. Rogakou;Chye Boon;Christophe Redon;William M. Bonner

  • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage.

    Tanya T Paull;Emmy P Rogakou;Vikky Yamazaki;Cordula U Kirchgessner

  • γH2AX and cancer

    William M. Bonner;Christophe E. Redon;Jennifer S. Dickey;Asako J. Nakamura

  • Genomic instability in mice lacking histone H2AX.

    Arkady Celeste;Simone Petersen;Peter J. Romanienko;Oscar Fernandez-Capetillo

  • Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

    Arkady Celeste;Oscar Fernandez-Capetillo;Michael J. Kruhlak;Duane R. Pilch

  • Histone H2A variants H2AX and H2AZ.

    Christophe Redon;Duane Pilch;Emmy Rogakou;Olga Sedelnikova

  • Recombinational DNA double-strand breaks in mice precede synapsis

    Shantha K. Mahadevaiah;James M.A. Turner;Frédéric Baudat;Emmy P. Rogakou

  • Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

    Olga A. Sedelnikova;Izumi Horikawa;Drazen B. Zimonjic;Nicholas C. Popescu

  • Initiation of DNA Fragmentation during Apoptosis Induces Phosphorylation of H2AX Histone at Serine 139

    Emmy P. Rogakou;Wilberto Nieves-Neira;Chye Boon;Yves Pommier

  • DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.

    Oscar Fernandez-Capetillo;Hua Tang Chen;Arkady Celeste;Irene Ward

  • Quantitative Detection of 125IdU-Induced DNA Double-Strand Breaks with γ-H2AX Antibody

    Olga A. Sedelnikova;Emmy P. Rogakou;Igor G. Panyutin;William M. Bonner

  • H2AX Haploinsufficiency Modifies Genomic Stability and Tumor Susceptibility

    Arkady Celeste;Simone Difilippantonio;Michael J. Difilippantonio;Oscar Fernandez-Capetillo

  • H2AX Is Required for Chromatin Remodeling and Inactivation of Sex Chromosomes in Male Mouse Meiosis

    Oscar Fernandez-Capetillo;Shantha K. Mahadevaiah;Arkady Celeste;Peter J. Romanienko

  • Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-dependent DNA Double-strand Breaks Induced by Mammalian DNA Topoisomerase I Cleavage Complexes

    Takahisa Furuta;Haruyuki Takemura;Zhi Yong Liao;Gregory J. Aune

  • Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break

    Robert Shroff;Ayelet Arbel-Eden;Duane Pilch;Grzegorz Ira

  • AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching

    Simone Petersen;Rafael Casellas;Bernardo Reina-San-Martin;Hua Tang Chen

  • Characteristics of γ-H2AX foci at DNA double-strand breaks sites

    Duane R Pilch;Olga A Sedelnikova;Christophe Redon;Arkady Celeste

  • p21: A Two-Faced Genome Guardian

    Alexandros G. Georgakilas;Olga A. Martin;William M. Bonner

  • Histone H2AX in DNA damage and repair.

    Olga A Sedelnikova;Duane R Pilch;Christophe Redon;William M Bonner

Frequent Co-Authors

Christophe E. Redon
Christophe E. Redon National Institutes of Health
Yves Pommier
Yves Pommier National Institutes of Health
André Nussenzweig
André Nussenzweig National Institutes of Health
Alexandros G. Georgakilas
Alexandros G. Georgakilas National Technical University of Athens
James H. Doroshow
James H. Doroshow National Institutes of Health
Kurt W. Kohn
Kurt W. Kohn National Institutes of Health
Olga Kovalchuk
Olga Kovalchuk University of Lethbridge
Oscar Fernandez-Capetillo
Oscar Fernandez-Capetillo Spanish National Cancer Research Centre
Drazen B. Zimonjic
Drazen B. Zimonjic National Institutes of Health
Nicholas C. Popescu
Nicholas C. Popescu National Institutes of Health

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