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Biology and Biochemistry

D-Index
56
Citations
19757
World Ranking
14164
National Ranking
5971

Overview

Christophe E. Redon is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a significant number of publications also contributing to medicine. Within these broad fields, subfields such as molecular biology, oncology, cancer research, epidemiology, and cell biology frequently emerge in their work.

Their scientific focus includes several main topics, notably DNA repair mechanisms, lung cancer research studies, cancer genomics and diagnostics, genomics and chromatin dynamics, cancer therapeutics and mechanisms, epigenetics and DNA methylation, and ubiquitin and proteasome pathways.

Among recent scholarly contributions, key papers include:

  • "Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress," 2021, Cancer Cell
  • "Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes," 2023, Cancer Discovery
  • "Regulation of cell cycle drivers by Cullin-RING ubiquitin ligases," 2020, Experimental & Molecular Medicine
  • "BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage," 2021, Nature Communications
  • "BAMscale: quantification of next-generation sequencing peaks and generation of scaled coverage tracks," 2020, Epigenetics & Chromatin

Frequent collaborators in Christophe E. Redon's work include:

  • Mirit I. Aladjem
  • Yves Pommier
  • Lőrinc Sándor Pongor
  • Haiqing Fu
  • Anish Thomas

Publications often appear in several recurrent venues such as Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Research Square, and Cancer Research Communications.

Best Publications

  • Megabase chromatin domains involved in DNA double-strand breaks in vivo.

    Emmy P. Rogakou;Chye Boon;Christophe Redon;William M. Bonner

  • γH2AX and cancer

    William M. Bonner;Christophe E. Redon;Jennifer S. Dickey;Asako J. Nakamura

  • Genomic instability in mice lacking histone H2AX.

    Arkady Celeste;Simone Petersen;Peter J. Romanienko;Oscar Fernandez-Capetillo

  • Histone H2A variants H2AX and H2AZ.

    Christophe Redon;Duane Pilch;Emmy Rogakou;Olga Sedelnikova

  • Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-dependent DNA Double-strand Breaks Induced by Mammalian DNA Topoisomerase I Cleavage Complexes

    Takahisa Furuta;Haruyuki Takemura;Zhi Yong Liao;Gregory J. Aune

  • AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching

    Simone Petersen;Rafael Casellas;Bernardo Reina-San-Martin;Hua Tang Chen

  • Characteristics of γ-H2AX foci at DNA double-strand breaks sites

    Duane R Pilch;Olga A Sedelnikova;Christophe Redon;Arkady Celeste

  • USE OF THE γ-H2AX ASSAY TO MONITOR DNA DAMAGE AND REPAIR IN TRANSLATIONAL CANCER RESEARCH

    Alesia Ivashkevich;Christophe E. Redon;Asako J. Nakamura;Roger F. Martin

  • Histone H2AX in DNA damage and repair.

    Olga A Sedelnikova;Duane R Pilch;Christophe Redon;William M Bonner

  • H2AX: functional roles and potential applications

    Jennifer S. Dickey;Christophe E. Redon;Asako J. Nakamura;Brandon J. Baird

  • Role of oxidatively induced DNA lesions in human pathogenesis

    Olga A. Sedelnikova;Christophe E. Redon;Jennifer S. Dickey;Asako J. Nakamura

  • Repair of and checkpoint response to topoisomerase I-mediated DNA damage.

    Yves Pommier;Christophe Redon;V.Ashutosh Rao;Jennifer A Seiler

  • Repair of topoisomerase I-mediated DNA damage.

    Yves Pommier;Juana M. Barcelo;Juana M. Barcelo;V. Ashutosh Rao;V. Ashutosh Rao;Olivier Sordet;Olivier Sordet

  • Histone γH2AX and Poly(ADP-Ribose) as Clinical Pharmacodynamic Biomarkers

    Christophe E Redon;Asako J Nakamura;Yong-Wei Zhang;Jiuping Jay Ji

  • γ-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin

    Christophe E. Redon;Jennifer S. Dickey;William M. Bonner;Olga A. Sedelnikova

  • Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage

    Christophe Redon;Duane R Pilch;Emmy P Rogakou;Ann H Orr

  • Ataxia telangiectasia mutated activation by transcription‐ and topoisomerase I‐induced DNA double‐strand breaks

    Olivier Sordet;Christophe E Redon;Josée Guirouilh‐Barbat;Susan Smith

  • Histone H2A Phosphorylation Controls Crb2 Recruitment at DNA Breaks, Maintains Checkpoint Arrest, and Influences DNA Repair in Fission Yeast

    Toru M. Nakamura;Li-Lin Du;Christophe Redon;Paul Russell

  • Delayed kinetics of DNA double-strand break processing in normal and pathological aging.

    Olga A. Sedelnikova;Izumi Horikawa;Christophe Redon;Asako Nakamura

  • SLFN11 Blocks Stressed Replication Forks Independently of ATR

    Junko Murai;Sai-Wen Tang;Elisabetta Leo;Simone A. Baechler

Frequent Co-Authors

William M. Bonner
William M. Bonner National Institutes of Health
Mirit I. Aladjem
Mirit I. Aladjem National Institutes of Health
Yves Pommier
Yves Pommier National Institutes of Health
Alexandros G. Georgakilas
Alexandros G. Georgakilas National Technical University of Athens
James H. Doroshow
James H. Doroshow National Institutes of Health
André Nussenzweig
André Nussenzweig National Institutes of Health
Susan E. Bates
Susan E. Bates Columbia University
Jane B. Trepel
Jane B. Trepel National Institutes of Health
William D. Figg
William D. Figg National Institutes of Health
Christophe Marchand
Christophe Marchand National Institutes of Health

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