Targeting the dynamic HSP90 complex in cancer
Jane Trepel;Mehdi Mollapour;Giuseppe Giaccone;Len Neckers.
Nature Reviews Cancer (2010)
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
Jennifer S. Isaacs;Yun Jin Jung;David R. Mole;Sunmin Lee.
Cancer Cell (2005)
IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis.
Yun-Jin Jung;Jennifer S. Isaacs;Sunmin Lee;Jane Trepel.
The FASEB Journal (2003)
Taxol-induced Apoptosis and Phosphorylation of Bcl-2 Protein Involves c-Raf-1 and Represents a Novel c-Raf-1 Signal Transduction Pathway
Mikhail V. Blagosklonny;Theodor Schulte;Phuongmai Nguyen;Jane Trepel.
Cancer Research (1996)
The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties.
Sara J. Felts;Barbara A.L. Owen;PhuongMai Nguyen;Jane Trepel.
Journal of Biological Chemistry (2000)
Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer
Alain Thibault;Dvorit Samid;Dvorit Samid;Anne C. Tompkins;William D. Figg.
Clinical Cancer Research (1996)
Phase I and Pharmacokinetic Study of MS-275, a Histone Deacetylase Inhibitor, in Patients With Advanced and Refractory Solid Tumors or Lymphoma
Qin C. Ryan;Donna Headlee;Milin Acharya;Alex Sparreboom.
Journal of Clinical Oncology (2005)
Randomized Phase II, Double-Blind, Placebo-Controlled Study of Exemestane With or Without Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Treatment With a Nonsteroidal Aromatase Inhibitor
Denise A. Yardley;Roohi R. Ismail-Khan;Bohuslav Melichar;Mikhail Lichinitser.
Journal of Clinical Oncology (2013)
p53 Inhibits Hypoxia-inducible Factor-stimulated Transcription *
Mikhail V. Blagosklonny;Won G. An;Larisa Y. Romanova;Jane Trepel.
Journal of Biological Chemistry (1998)
p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2.
Christine Chavany;Edward Mimnaugh;Penny Miller;Roberto Bitton.
Journal of Biological Chemistry (1996)
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