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Biology and Biochemistry

D-Index
50
Citations
7763
World Ranking
17738
National Ranking
784

Overview

Els Verhoeyen is affiliated with Inserm: Institut national de la santé et de la recherche médicale in France. Their research spans multiple domains within biomedicine, including immunology, molecular biology, genetics, and oncology. Their work primarily explores cellular immunology, gene therapy, and cancer immunotherapy.

Verhoeyen has been involved in publishing extensively, with recent papers highlighting significant research contributions. Notable publications include:

  • Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy, 2020, Immunity
  • Lentiviral Vector Pseudotypes: Precious Tools to Improve Gene Modification of Hematopoietic Cells for Research and Gene Therapy, 2020, Viruses
  • Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice, 2021, Nature Microbiology
  • Humanized Mice Are Precious Tools for Preclinical Evaluation of CAR T and CAR NK Cell Therapies, 2020, Cancers
  • Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity, 2022, Journal for ImmunoTherapy of Cancer

Their frequent coauthors include:

  • Adrien Krug
  • Alejandra Gutiérrez-Guerrero
  • Rana Mhaidly
  • Jean-Ehrland Ricci
  • Elizabeth Macintyre

Common publication venues where Verhoeyen frequently publishes research are:

  • Cancers (6 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (6 publications)
  • Human Gene Therapy (4 publications)
  • Molecular Therapy - Nucleic Acids (3 publications)
  • Cytotherapy (3 publications)

Main fields of study for Verhoeyen include:

  • Biochemistry, Genetics and Molecular Biology (70 publications)
  • Medicine (65 publications)
  • Immunology and Microbiology (32 publications)

Within these fields, they focus on several subfields such as:

  • Molecular Biology (44 publications)
  • Immunology (31 publications)
  • Oncology (28 publications)
  • Genetics (20 publications)
  • Hematology (9 publications)

Key topics in Verhoeyen's research portfolio include:

  • CAR-T cell therapy research (48 publications)
  • Virus-based gene therapy research (34 publications)
  • Immune Cell Function and Interaction (32 publications)
  • CRISPR and Genetic Engineering (24 publications)
  • T-cell and B-cell Immunology (16 publications)
  • Viral Infectious Diseases and Gene Expression in Insects (12 publications)
  • Lymphoma Diagnosis and Treatment (12 publications)

Best Publications

  • Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists.

    Stéphane Prost;Francis Relouzat;Marc Spentchian;Yasmine Ouzegdouh

  • Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins.

    Philippe E. Mangeot;Valérie Risson;Floriane Fusil;Aline Marnef

  • Parkin-Independent Mitophagy Controls Chemotherapeutic Response in Cancer Cells

    Elodie Villa;Emma Proïcs;Camila Rubio-Patiño;Sandrine Obba

  • Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor

    Fouzia Amirache;Camille Lévy;Caroline Costa;Philippe-Emmanuel Mangeot

  • TRF2 and Apollo Cooperate with Topoisomerase 2α to Protect Human Telomeres from Replicative Damage

    Jing Ye;Christelle Lenain;Serge Bauwens;Angela Rizzo

  • IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential

    Sonia Boulakirba;Anja Pfeifer;Rana Mhaidly;Sandrine Obba

  • The TLR1/2 agonist PAM(3)CSK(4) instructs commitment of human hematopoietic stem cells to a myeloid cell fate.

    K. De Luca;V. Frances-Duvert;V. Frances-Duvert;M.-J. Asensio;M.-J. Asensio;R. Ihsani;R. Ihsani

  • Stable transduction of quiescent T-cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins

    Cecilia Frecha;Caroline Costa;Didier Nègre;Emmanuel Gauthier

  • IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes

    Els Verhoeyen;Valerie Dardalhon;Valerie Dardalhon;Odile Ducrey-Rundquist;Odile Ducrey-Rundquist;Didier Trono;Didier Trono

  • Glut1-mediated glucose transport regulates HIV infection

    Séverine Loisel-Meyer;Louise Swainson;Marco Craveiro;Leal Oburoglu

  • In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

    Anett Pfeiffer;Frederic Bastian Thalheimer;Sylvia Hartmann;Annika Frank

  • TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells

    Annamaria Biroccio;Julien Cherfils-Vicini;Adeline Augereau;Adeline Augereau;Sébastien Pinte;Sébastien Pinte

  • Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs

    Anais Girard-Gagnepain;Fouzia Amirache;Caroline Costa;Camille Lévy

  • Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8 + T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

    Marianne Weulersse;Assia Asrir;Andrea C. Pichler;Lea Lemaitre

  • Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell–activating polypeptide

    Marielle Maurice;Els Verhoeyen;Patrick Salmon;Didier Trono

  • Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance

    Camila Rubio-Patiño;Jozef P. Bossowski;Gian Marco De Donatis;Laura Mondragón

  • Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector.

    Aurelien B. L. Colamartino;William Lemieux;Panojot Bifsha;Simon Nicoletti

  • Surface-engineering of lentiviral vectors

    Els Verhoeyen;Francois-Lo ¨ õc Cosset

  • Epigenetic silencing and tissue independent expression of a novel tetracycline inducible system in double-transgenic pigs

    Wilfried A. Kues;Reinhard Schwinzer;Dagmar Wirth;Els Verhoeyen

  • Erosion Of The Chronic Myeloid Leukemia Stem Cell Pool By PPARγ Agonists

    Francis Relouzat;Marc Spenchian;Gérald Massonnet;Jean-Paul Beressi

Frequent Co-Authors

François-Loïc Cosset
François-Loïc Cosset Claude Bernard University Lyon 1
Christian J. Buchholz
Christian J. Buchholz Paul Ehrlich Institut
Hansjörg Hauser
Hansjörg Hauser Helmholtz Centre for Infection Research
Elizabeth Macintyre
Elizabeth Macintyre Necker-Enfants Malades Hospital
Dimitri Lavillette
Dimitri Lavillette Chinese Academy of Sciences
Jean-Ehrland Ricci
Jean-Ehrland Ricci Université Côte d'Azur
Didier Trono
Didier Trono École Polytechnique Fédérale de Lausanne
Naomi Taylor
Naomi Taylor National Institutes of Health
Winfried S. Wels
Winfried S. Wels Goethe University Frankfurt

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