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Dimitri Lavillette

Dimitri Lavillette

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
9702
World Ranking
18637
National Ranking
492

Overview

Dimitri Lavillette is affiliated with the Chinese Academy of Sciences in China. Their primary research focus lies within the field of Medicine, with a specialization in Infectious Diseases. Additional areas of study include Molecular Biology, Radiology, Nuclear Medicine and Imaging, Animal Science and Zoology, and Ecology.

The scientist's research topics cover various aspects of viral infections and immunology, particularly centered on coronaviruses and COVID-19. Key themes in their work include:

  • SARS-CoV-2 and COVID-19 Research
  • Monoclonal and Polyclonal Antibodies Research
  • COVID-19 Clinical Research Studies
  • Animal Virus Infections Studies
  • Bacteriophages and Microbial Interactions
  • Viral Gastroenteritis Research and Epidemiology
  • Mosquito-Borne Diseases and Control

Dimitri Lavillette has published extensively in several scientific journals. Frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens
  • Nature Communications
  • Cell Discovery
  • Journal of Biological Chemistry

Representative recent papers include:

  • "The SARS-CoV-2 envelope and membrane proteins modulate maturation and retention of the spike protein, allowing assembly of virus-like particles" (2020, Journal of Biological Chemistry)
  • "SARS-CoV-2 spike engagement of ACE2 primes S2' site cleavage and fusion initiation" (2021, Proceedings of the National Academy of Sciences)
  • "Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections" (2021, Nature Communications)
  • "A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection" (2021, Nature Communications)
  • "Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement" (2020, Cell Discovery)

The scientist has collaborated regularly with several co-authors including Bingjie Zhou, Dianfan Li, Zhong Huang, Chao Zhang, and Shiqi Xu. Their partnerships reflect focused research efforts in the investigation of viral mechanisms and antibody responses.

Best Publications

  • EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

    Joachim Lupberger;Mirjam B Zeisel;Mirjam B Zeisel;Fei Xiao;Fei Xiao;Christine Thumann;Christine Thumann

  • An Envelope Glycoprotein of the Human Endogenous Retrovirus HERV-W Is Expressed in the Human Placenta and Fuses Cells Expressing the Type D Mammalian Retrovirus Receptor

    Jean-Luc Blond;Dimitri Lavillette;Valérie Cheynet;Olivier Bouton

  • An Interplay between Hypervariable Region 1 of the Hepatitis C Virus E2 Glycoprotein, the Scavenger Receptor BI, and High-Density Lipoprotein Promotes both Enhancement of Infection and Protection against Neutralizing Antibodies

    Birke Bartosch;Géraldine Verney;Marlène Dreux;Peggy Donot

  • Human serum facilitates hepatitis C virus infection, and neutralizing responses inversely correlate with viral replication kinetics at the acute phase of hepatitis C virus infection.

    Dimitri Lavillette;Yoann Morice;Georgios Germanidis;Peggy Donot

  • Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus.

    Dimitri Lavillette;Alexander W. Tarr;Cécile Voisset;Peggy Donot

  • Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein

    Ania Owsianka;Alexander W. Tarr;Vicky S. Juttla;Dimitri Lavillette

  • The SARS-CoV-2 Envelope and Membrane proteins modulate maturation and retention of the Spike protein, allowing assembly of virus-like particles.

    Bertrand Boson;Vincent Legros;Bingjie Zhou;Eglantine Siret

  • The Tight Junction Proteins Claudin-1, -6, and -9 Are Entry Cofactors for Hepatitis C Virus

    Laurent Meertens;Claire Bertaux;Lisa Cukierman;Emmanuel Cormier

  • High density lipoprotein inhibits hepatitis C virus-neutralizing antibodies by stimulating cell entry via activation of the scavenger receptor BI.

    Marlène Dreux;Marlène Dreux;Thomas Pietschmann;Christelle Granier;Christelle Granier;Cécile Voisset

  • Characterization of Fusion Determinants Points to the Involvement of Three Discrete Regions of Both E1 and E2 Glycoproteins in the Membrane Fusion Process of Hepatitis C Virus

    Dimitri Lavillette;Eve-Isabelle Pécheur;Peggy Donot;Judith Fresquet

  • The Envelope Glycoprotein of Human Endogenous Retrovirus Type W Uses a Divergent Family of Amino Acid Transporters/Cell Surface Receptors

    Dimitri Lavillette;Mariana Marin;Alessia Ruggieri;François Mallet

  • Fusogenic Membrane Glycoproteins As a Novel Class of Genes for the Local and Immune-mediated Control of Tumor Growth

    Andrew Bateman;Francis Bullough;Stephen Murphy;Lisa Emiliusen

  • The Tight Junction-Associated Protein Occludin Is Required for a Postbinding Step in Hepatitis C Virus Entry and Infection

    Ignacio Benedicto;Francisca Molina-Jiménez;Birke Bartosch;François-Loïc Cosset;François-Loïc Cosset;François-Loïc Cosset

  • Kinases required in hepatitis C virus entry and replication highlighted by small interference RNA screening

    Maud Trotard;Maud Trotard;Charlotte Lepère-Douard;Charlotte Lepère-Douard;Morgane Régeard;Morgane Régeard;Claire Piquet-Pellorce

  • Hepatitis C Virus Glycoproteins Mediate Low pH-dependent Membrane Fusion with Liposomes *

    Dimitri Lavillette;Birke Bartosch;Delphine Nourrisson;Gérelidine Verney

  • Receptor complementation and mutagenesis reveal SR-BI as an essential HCV entry factor and functionally imply its intra- and extra-cellular domains.

    Marlène Dreux;Viet Loan Dao Thi;Judith Fresquet;Maryse Guérin

  • A Prime-Boost Strategy Using Virus-Like Particles Pseudotyped for HCV Proteins Triggers Broadly Neutralizing Antibodies in Macaques

    Pierre Garrone;Anne-Catherine Fluckiger;Philippe E. Mangeot;Emmanuel Gauthier

  • Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.

    Viet Loan Dao Thi;Christelle Granier;Mirjam B. Zeisel;Mirjam B. Zeisel;Maryse Guérin

  • N-Linked Glycosylation and Sequence Changes in a Critical Negative Control Region of the ASCT1 and ASCT2 Neutral Amino Acid Transporters Determine Their Retroviral Receptor Functions

    Mariana Marin;Dimitri Lavillette;Sean M. Kelly;David Kabat

  • A proline-rich motif downstream of the receptor binding domain modulates conformation and fusogenicity of murine retroviral envelopes

    Dimitri Lavillette;Marielle Maurice;Catherine Roche;Stephen J. Russell

Frequent Co-Authors

François-Loïc Cosset
François-Loïc Cosset Claude Bernard University Lyon 1
Mirjam B. Zeisel
Mirjam B. Zeisel University of Strasbourg
Thomas F. Baumert
Thomas F. Baumert University of Strasbourg
Els Verhoeyen
Els Verhoeyen Inserm : Institut national de la santé et de la recherche médicale
Jean Dubuisson
Jean Dubuisson Institut Pasteur
Arvind H. Patel
Arvind H. Patel University of Glasgow
David Kabat
David Kabat Oregon Health & Science University

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