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Biology and Biochemistry

D-Index
72
Citations
14975
World Ranking
6442
National Ranking
232

Overview

Olga Kovalchuk is a researcher affiliated with the University of Lethbridge in Canada. Their academic work spans multiple fields of study, predominantly focusing on Medicine and Biochemistry, Genetics and Molecular Biology.

Their research output includes significant contributions to the areas of Pharmacology, Molecular Biology, Plant Science, Clinical Psychology, and Cancer Research. The thematic focus of their publications revolves around key topics such as Cannabis and Cannabinoid Research, Pancreatic function and diabetes, Psychedelics and Drug Studies, GABA and Rice Research, Tryptophan and brain disorders, Inflammasome and immune disorders, and Immune Cell Function and Interaction.

Among the recent papers attributed to or associated with this scientific field are:

  • The Role of microRNAs in Organismal and Skin Aging, 2020, International Journal of Molecular Sciences
  • In search of preventative strategies: novel high-CBD cannabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissues, 2020, Aging
  • Cannabinoids as anticancer therapeutic agents, 2020, Cell Cycle
  • Stress, diet, exercise: Common environmental factors and their impact on epigenetic age, 2023, Ageing Research Reviews
  • Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective, 2021, Frontiers in Immunology

Olga Kovalchuk collaborates frequently with a set of coauthors, including:

  • Igor Kovalchuk
  • Yaroslav Ilnytskyy
  • Bo Wang
  • Esmaeel Ghasemi Gojani
  • Dongping Li

Their work has been published multiple times in specific journals, notably:

  • International Journal of Molecular Sciences
  • Molecules
  • Problems of Social Hygiene Public Health and History of Medicine
  • Cancers
  • Preprints.org

Best Publications

  • Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin

    Olga Kovalchuk;Jody Filkowski;James Meservy;Yaroslav Ilnytskyy

  • Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond.

    Lidiya Luzhna;Palak Kathiria;Olga Kovalchuk

  • Alterations of microRNAs and their targets are associated with acquired resistance of MCF‐7 breast cancer cells to cisplatin

    Igor P. Pogribny;Jody N. Filkowski;Volodymyr P. Tryndyak;Andrey Golubov

  • Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location

    Carole Yauk;Aris Polyzos;Andrea Rowan-Carroll;Christopher M. Somers

  • Pathogen-induced systemic plant signal triggers DNA rearrangements

    Igor Kovalchuk;Olga Kovalchuk;Véronique Kalck;Vitaly Boyko

  • Genome hypermethylation in Pinus silvestris of Chernobyl--a mechanism for radiation adaptation?

    Olga Kovalchuk;Paula Burke;Andrey Arkhipov;Nikolaj Kuchma

  • DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models.

    Olga A. Sedelnikova;Asako Nakamura;Olga Kovalchuk;Igor Koturbash

  • Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo.

    I Koturbash;R E Rugo;C A Hendricks;J Loree

  • Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo.

    Igor Koturbash;Alex Boyko;Rocio Rodriguez-Juarez;Robert J. McDonald

  • Role of ferritin alterations in human breast cancer cells.

    Svitlana I. Shpyleva;Volodymyr P. Tryndyak;Olga Kovalchuk;Athena Starlard-Davenport

  • Dose-dependence, sex- and tissue-specificity, and persistence of radiation-induced genomic DNA methylation changes.

    Igor Pogribny;Joe Raiche;Mark Slovack;Olga Kovalchuk

  • Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring.

    Fabiola C. R. Zucchi;Youli Yao;Isaac D. Ward;Yaroslav Ilnytskyy

  • Molecular aspects of plant adaptation to life in the Chernobyl zone

    Igor Kovalchuk;Vladimir Abramov;Igor Pogribny;Olga Kovalchuk

  • Fractionated Low-Dose Radiation Exposure Leads to Accumulation of DNA Damage and Profound Alterations in DNA and Histone Methylation in the Murine Thymus

    Igor Pogribny;Igor Koturbash;Volodymyr Tryndyak;Darryl Hudson

  • Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins.

    Volodymyr P Tryndyak;Olga Kovalchuk;Igor P Pogribny

  • Population Specific Biomarkers of Human Aging: A Big Data Study Using South Korean, Canadian, and Eastern European Patient Populations.

    Polina Mamoshina;Kirill Kochetov;Kirill Kochetov;Evgeny Putin;Evgeny Putin;Franco Cortese

  • Epigenetic changes and nontargeted radiation effects--is there a link?

    Olga Kovalchuk;Janet E. Baulch

  • The Allium cepa chromosome aberration test reliably measures genotoxicity of soils of inhabited areas in the Ukraine contaminated by the Chernobyl accident.

    Olga Kovalchuk;Igor Kovalchuk;Andrey Arkhipov;Polina Telyuk

  • Epigenetic changes in patients with multiple sclerosis

    Marcus W. Koch;Luanne M. Metz;Olga Kovalchuk

  • Epigenetics in Health and Disease

    Igor Kovalchuk;Olga Kovalchuk

Frequent Co-Authors

Igor Kovalchuk
Igor Kovalchuk University of Lethbridge
Igor P. Pogribny
Igor P. Pogribny National Center for Toxicological Research
Bryan Kolb
Bryan Kolb University of Lethbridge
Anton Buzdin
Anton Buzdin Sechenov University
Frank A. Hegmann
Frank A. Hegmann University of Alberta
Barbara Hohn
Barbara Hohn Friedrich Miescher Institute
Frederick A. Beland
Frederick A. Beland National Center for Toxicological Research
Gerlinde A. S. Metz
Gerlinde A. S. Metz University of Lethbridge
Charles R. Cantor
Charles R. Cantor Boston University
William M. Bonner
William M. Bonner National Institutes of Health

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