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D-Index & Metrics

Molecular Biology

D-Index
61
Citations
23597
World Ranking
1878
National Ranking
26

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Oscar Fernandez-Capetillo is affiliated with the Spanish National Cancer Research Centre in Spain. Their research primarily spans the disciplines of Biochemistry, Genetics and Molecular Biology, alongside contributions to Medicine. Within these broad fields, the scientist focuses on Molecular Biology, Cell Biology, Infectious Diseases, Oncology, and Immunology as key subfields.

Their work covers several main topics, including:

  • DNA Repair Mechanisms
  • SARS-CoV-2 and COVID-19 Research
  • RNA modifications and cancer
  • Ubiquitin and proteasome pathways
  • Mitochondrial Function and Pathology
  • Bacteriophages and microbial interactions
  • Endoplasmic Reticulum Stress and Disease

Oscar Fernandez-Capetillo has published extensively, with frequent contributions appearing in venues such as bioRxiv (Cold Spring Harbor Laboratory), The EMBO Journal, Nature Communications, Molecular Oncology, and Aging. The most common publication venue is bioRxiv with 15 papers, followed by multiple publications in The EMBO Journal, Nature Communications, Molecular Oncology, and Aging.

Recent papers authored or co-authored by the scientist include:

  • "A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo" (2022, Nature Communications)
  • "Targeting the nucleolus as a therapeutic strategy in human disease" (2022, Trends in Biochemical Sciences)
  • "ATR expands embryonic stem cell fate potential in response to replication stress" (2020, eLife)
  • "USP7 limits CDK1 activity throughout the cell cycle" (2021, The EMBO Journal)
  • "Widespread displacement of DNA- and RNA-binding factors underlies toxicity of arginine-rich cell-penetrating peptides" (2021, The EMBO Journal)

The scientist collaborates regularly with several frequent co-authors, including Maria Häggblad, Matilde Murga, Daniela Hühn, Vanesa Lafarga, and Bartłomiej Porębski, indicating an active network of research partnerships.

Oscar Fernandez-Capetillo has been recognized as a Member of the European Molecular Biology Organization (EMBO), reflecting their standing in the molecular biology community.

Best Publications

  • 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

    Samuel F. Bunting;Elsa Callén;Nancy Wong;Hua Tang Chen

  • Genomic instability in mice lacking histone H2AX.

    Arkady Celeste;Simone Petersen;Peter J. Romanienko;Oscar Fernandez-Capetillo

  • H2AX: the histone guardian of the genome.

    Oscar Fernandez-Capetillo;Alicia Lee;Michel Nussenzweig;André Nussenzweig

  • Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

    Arkady Celeste;Oscar Fernandez-Capetillo;Michael J. Kruhlak;Duane R. Pilch

  • A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

    Rosa M. Marión;Katerina Strati;Han Li;Matilde Murga

  • Replication fork stability confers chemoresistance in BRCA-deficient cells

    Arnab Ray Chaudhuri;Elsa Callen;Xia Ding;Ewa Gogola

  • DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.

    Oscar Fernandez-Capetillo;Hua Tang Chen;Arkady Celeste;Irene Ward

  • Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

    Daniel Herranz;Maribel Muñoz-Martin;Marta Cañamero;Francisca Mulero

  • H2AX Haploinsufficiency Modifies Genomic Stability and Tumor Susceptibility

    Arkady Celeste;Simone Difilippantonio;Michael J. Difilippantonio;Oscar Fernandez-Capetillo

  • H2AX Is Required for Chromatin Remodeling and Inactivation of Sex Chromosomes in Male Mouse Meiosis

    Oscar Fernandez-Capetillo;Shantha K. Mahadevaiah;Arkady Celeste;Peter J. Romanienko

  • Silencing of unsynapsed meiotic chromosomes in the mouse.

    James M A Turner;Shantha K Mahadevaiah;Oscar Fernandez-Capetillo;André Nussenzweig

  • Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

    Michael J. Kruhlak;Arkady Celeste;Graham Dellaire;Oscar Fernandez-Capetillo

  • A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

    Luis I Toledo;Matilde Murga;Rafal Zur;Rebeca Soria

  • Identification of Early Replicating Fragile Sites that Contribute to Genome Instability

    Jacqueline H. Barlow;Robert B. Faryabi;Elsa Callén;Nancy Wong

  • Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors

    Matilde Murga;Stefano Campaner;Andres J Lopez-Contreras;Luis I Toledo

  • Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

    Paula Martínez;Maria Thanasoula;Purificación Muñoz;Chunyan Liao

  • A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

    Matilde Murga;Samuel Bunting;Maria F Montaña;Rebeca Soria

  • 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions

    Elsa Callen;Michela Di Virgilio;Michael J. Kruhlak;Maria Nieto-Soler

  • Cdk2 suppresses cellular senescence induced by the c-myc oncogene.

    Stefano Campaner;Mirko Doni;Per Hydbring;Per Hydbring;Alessandro Verrecchia

  • ATM regulates ATR chromatin loading in response to DNA double-strand breaks

    Myriam Cuadrado;Barbara Martinez-Pastor;Matilde Murga;Luis I. Toledo

Frequent Co-Authors

André Nussenzweig
André Nussenzweig National Institutes of Health
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Maria A. Blasco
Maria A. Blasco Spanish National Cancer Research Centre
Elsa Callen
Elsa Callen National Institutes of Health
Georg Stoecklin
Georg Stoecklin Heidelberg University
Manuel Serrano
Manuel Serrano Institució Catalana de Recerca i Estudis Avançats
William M. Bonner
William M. Bonner National Institutes of Health
Sven Rottenberg
Sven Rottenberg University of Bern
Sagrario Ortega
Sagrario Ortega Spanish National Research Council
R. Daniel Camerini-Otero
R. Daniel Camerini-Otero National Institutes of Health

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