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Molecular Biology

D-Index
73
Citations
20693
World Ranking
1270
National Ranking
653

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Tej K. Pandita is affiliated with Houston Methodist in the United States and works primarily in the field of Biochemistry, Genetics and Molecular Biology. Their research contributions span multiple subfields, including Molecular Biology, Cancer Research, Cell Biology, Neurology, and Geriatrics and Gerontology.

The main topics of Pandita's work involve DNA Repair Mechanisms, Carcinogens and Genotoxicity Assessment, CRISPR and Genetic Engineering, Cell death mechanisms and regulation, Sirtuins and Resveratrol in Medicine, Histone Deacetylase Inhibitors Research, and Microtubule and mitosis dynamics.

Frequent publication venues for their work include Molecular and Cellular Biology, bioRxiv (Cold Spring Harbor Laboratory), iScience, Oncogene, and Oncotarget.

Notable recent publications by Tej K. Pandita are:

  • Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks, 2022, iScience
  • Caspase-2 regulates S-phase cell cycle events to protect from DNA damage accumulation independent of apoptosis, 2021, Oncogene
  • Esomeprazole enhances the effect of ionizing radiation to improve tumor control, 2021, Oncotarget
  • Implications of Translesion DNA Synthesis Polymerases on Genomic Stability and Human Health, 2023, Molecular and Cellular Biology
  • Stress Responses as Master Keys to Epigenomic Changes in Transcriptome and Metabolome for Cancer Etiology and Therapeutics, 2021, Molecular and Cellular Biology

Tej K. Pandita has collaborated frequently with several coauthors, including:

  • Raj K. Pandita
  • Kenneth S. Ramos
  • Vipin Singh
  • Krishna Moorthi Bhat
  • Chandrima Das

The scientist has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2013.

Best Publications

  • hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

    Homayoun Vaziri;Scott K. Dessain;Scott K. Dessain;Elinor Ng Eaton;Shin Ichiro Imai

  • c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability.

    Omid Vafa;Mark Wade;Suzanne Kern;Michelle Beeche

  • High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer

    Anne T. Ferguson;Ella Evron;Christopher B. Umbricht;Tej K. Pandita

  • ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

    Andrea L. Bredemeyer;Girdhar G. Sharma;Ching Yu Huang;Beth A. Helmink

  • ATM functions at the peroxisome to induce pexophagy in response to ROS

    Jiangwei Zhang;Durga Nand Tripathi;Ji Jing;Angela Alexander

  • Lack of PTEN sequesters CHK1 and initiates genetic instability

    Janusz Puc;Megan Keniry;Hong Shen Li;Tej K. Pandita

  • MOF and Histone H4 Acetylation at Lysine 16 Are Critical for DNA Damage Response and Double-Strand Break Repair

    Girdhar G. Sharma;Sairei So;Arun Gupta;Rakesh Kumar;Rakesh Kumar

  • hTERT associates with human telomeres and enhances genomic stability and DNA repair

    Girdhar G Sharma;Girdhar G Sharma;Arun Gupta;Arun Gupta;Huichen Wang;Harry Scherthan

  • Genomic Instability and Enhanced Radiosensitivity in Hsp70.1- and Hsp70.3-Deficient Mice

    Clayton R. Hunt;David J. Dix;Girdhar G. Sharma;Raj K. Pandita

  • Involvement of human MOF in ATM function

    Arun Gupta;Girdhar G. Sharma;Charles S H Young;Manjula Agarwal

  • Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

    Derek J. Richard;Emma Bolderson;Liza Cubeddu;Liza Cubeddu;Ross I. M. Wadsworth

  • The TIP60 complex regulates bivalent chromatin recognition by 53BP1 through direct H4K20me binding and H2AK15 acetylation

    Karine Jacquet;Amélie Fradet-Turcotte;Amélie Fradet-Turcotte;Nikita Avvakumov;Jean-Philippe Lambert

  • Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy

    Yonghua Yang;Warren Fiskus;Bao Yong;Peter Atadja

  • The Mammalian Ortholog of Drosophila MOF That Acetylates Histone H4 Lysine 16 Is Essential for Embryogenesis and Oncogenesis

    Arun Gupta;T. Geraldine Guerin-Peyrou;Girdhar G. Sharma;Changwon Park

  • Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase.

    S. Kharbanda;V. Kumar;S. Dhar;P. Pandey

  • The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function.

    Weiming Fu;Michael Killen;Carsten Culmsee;Sonu Dhar

  • ATM function and telomere stability.

    Tej K Pandita

  • Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells.

    Tej K. Pandita;S. Pathak;C. R. Geard

  • Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.

    Emma Bolderson;Nozomi Tomimatsu;Derek J. Richard;Didier Boucher

  • Fragments of ATM which have dominant-negative or complementing activity.

    Susan E. Morgan;Christine Lovly;Tej K. Pandita;Yosef Shiloh

Frequent Co-Authors

Raj K. Pandita
Raj K. Pandita Houston Methodist
Walter N. Hittelman
Walter N. Hittelman The University of Texas MD Anderson Cancer Center
Kum Kum Khanna
Kum Kum Khanna Mater Research
Jerry W. Shay
Jerry W. Shay The University of Texas Southwestern Medical Center
Saraswati Sukumar
Saraswati Sukumar Johns Hopkins University School of Medicine
Simon N. Powell
Simon N. Powell Memorial Sloan Kettering Cancer Center
Michael B. Kastan
Michael B. Kastan Duke University
Thomas Ludwig
Thomas Ludwig Columbia University
Eric J. Hall
Eric J. Hall Columbia University
Woodring E. Wright
Woodring E. Wright The University of Texas Southwestern Medical Center

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