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D-Index
83
Citations
26382
World Ranking
15570
National Ranking
7846

Overview

Walter N. Hittelman is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions also in the field of medicine.

Their work spans several subfields, including molecular biology, radiology, nuclear medicine and imaging, pathology and forensic medicine, biotechnology, and oncology. The main topics covered by their research include ubiquitin and proteasome pathways, DNA repair mechanisms, cancer mechanisms and therapy, cancer research and treatments, monoclonal and polyclonal antibodies research, glycosylation and glycoproteins research, and radiopharmaceutical chemistry and applications.

Walter N. Hittelman has published articles in various scientific venues with a notable concentration in Cancer Research. The frequent publication venues include:

  • Cancer Research
  • Haematologica
  • Journal for ImmunoTherapy of Cancer
  • Clinical Cancer Research

The following papers provide insight into their recent work and areas of study:

  • Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma, 2020, Haematologica
  • Therapeutic efficacy and safety of a human fusion construct targeting the TWEAK receptor Fn14 and containing a modified granzyme B, 2020, Journal for ImmunoTherapy of Cancer
  • Abstract PR08: Inhibition of ATR as a therapeutic strategy to overcome cisplatin resistance in HNSCC, 2020, Clinical Cancer Research
  • Abstract 5176: A novel, completely human fusion construct containing active Granzyme B efficiently kills Folate Receptor alpha positive tumor cells, 2020, Cancer Research
  • Abstract 3439: An internalizing anti-CEA construct for targeted delivery of granzyme B results in significant antitumor activity in human lung carcinoma xenografts, 2022, Cancer Research

Collaborations are an integral part of their research. Frequent co-authors include:

  • Ana Álvarez-Cienfuegos
  • Khalid A. Mohamedali
  • Michael G. Rosenblum
  • Lawrence H. Cheung
  • Aloke Sarkar

Best Publications

  • The Effect of Celecoxib, a Cyclooxygenase-2 Inhibitor, in Familial Adenomatous Polyposis

    Gideon Steinbach;Patrick M. Lynch;Robin K S Phillips;Marina H. Wallace

  • Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid).

    Raymond P. Warrell;Stanley R. Frankel;Wilson H. Miller;David A. Scheinberg

  • Effects of recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes.

    Saroj Vadhan-Raj;Michael Keating;Michael Keating;Anne Lemaistre;Anne Lemaistre;Walter N. Hittelman;Walter N. Hittelman

  • Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment

    Li Mao;Jin S. Lee;You H. Fan;Jae Y. Ro

  • Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle.

    Margarete M. S. Heck;Walter N. Hittelman;William C. Earnshaw

  • Clonal Genetic Alterations in the Lungs of Current and Former Smokers

    Li Mao;Jin Soo Lee;Jonathan M Kurie;You Hong Fan

  • Predicting cancer development in oral leukoplakia: ten years of translational research.

    J. Jack Lee;Waun Ki Hong;Walter N. Hittelman;Li Mao

  • Dysregulation of Epidermal Growth Factor Receptor Expression in Premalignant Lesions during Head and Neck Tumorigenesis

    Dong M. Shin;Jae Y. Ro;Waun Ki Hong;Walter N. Hittelman

  • A Missense Mutation in KIT Kinase Domain 1 Correlates with Imatinib Resistance in Gastrointestinal Stromal Tumors

    Lei L. Chen;Jonathan C. Trent;Elsie F. Wu;Gregory N. Fuller

  • Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-β-D-arabinosyl-2-fluoroadenine

    L. E. Robertson;Sherri Chubb;Raymond E. Meyn;Michael Story

  • Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis

    Dong M. Shin;Jhingook Kim;Jae Y. Ro;Jason Hittelman

  • Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer.

    Saroj Vadhan-Raj;Lesley J. Murray;Carlos Bueso-Ramos;Shreyaskumar Patel

  • Expression of blood-group antigen a — a favorable prognostic factor in non-small-cell lung cancer

    Jin S. Lee;Jae Y. Ro;Aysegul A. Sahin;Waun K. Hong

  • Aromatic DNA Adducts in Adjacent Tissues of Breast Cancer Patients: Clues to Breast Cancer Etiology

    Donghui Li;Mianying Wang;Kapil Dhingra;Walter N. Hittelman

  • p53 Expression: Predicting Recurrence and Second Primary Tumors in Head and Neck Squamous Cell Carcinoma

    D. M. Shin;J. S. Lee;S. M. Lippman;J. J. Lee

  • ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells

    Kristine S. Klos;Shannon L. Wyszomierski;Menghong Sun;Ming Tan

  • Biomarkers as intermediate end points in chemoprevention trials.

    Scott M. Lippman;Jin S. Lee;Reuben Lotan;Walter Hittelman

  • Stimulation of Myelopoiesis in Patients with Aplastic Anemia by Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor

    Saroj Vadhan-Raj;Stephen Buescher;Hal E. Broxmeyer;Anne Lemaistre

  • The Repair of Double-Strand DNA Breaks Correlates with Radiosensitivity of L5178Y-S and L5178Y-R Cells

    Danuta Wlodek;Walter N. Hittelman

  • DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma

    Se Kyu Kim;Youhong Fan;Vassiliki A Papadimitrakopoulou;Gary Clayman

Frequent Co-Authors

Waun Ki Hong
Waun Ki Hong The University of Texas MD Anderson Cancer Center
Scott M. Lippman
Scott M. Lippman University of California, San Diego
Jae Y. Ro
Jae Y. Ro Cornell University
Tej K. Pandita
Tej K. Pandita Houston Methodist
J. Jack Lee
J. Jack Lee The University of Texas MD Anderson Cancer Center
Dong M. Shin
Dong M. Shin Emory University
Reuben Lotan
Reuben Lotan The University of Texas MD Anderson Cancer Center
Yu Cao
Yu Cao University of Minnesota
Jaffer A. Ajani
Jaffer A. Ajani The University of Texas MD Anderson Cancer Center
Luka Milas
Luka Milas The University of Texas MD Anderson Cancer Center

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