World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

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Best Female Scientists

D-Index
122
Citations
53143
World Ranking
504
National Ranking
297

Medicine

D-Index
125
Citations
54721
World Ranking
3110
National Ranking
1717

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Margaret R. Spitz is affiliated with Baylor College of Medicine in the United States. Their research primarily touches on the fields of Biochemistry, Genetics, and Molecular Biology, with specific attention to molecular biology, genetics, pulmonary and respiratory medicine, cancer research, and oncology.

The scientist's work covers several main topics, including RNA modifications and cancer, cancer genomics and diagnostics, epigenetics and DNA methylation, genetic associations and epidemiology, BRCA gene mutations in cancer, lung cancer diagnosis and treatment, as well as lung cancer treatments and mutations.

Recent publications by Margaret R. Spitz include:

  • "Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer" (2022, Nature Genetics)
  • "Blood-Based Biomarker Panel for Personalized Lung Cancer Risk Assessment" (2022, Journal of Clinical Oncology)
  • "Rare deleterious germline variants and risk of lung cancer" (2021, npj Precision Oncology)
  • "Trans-ethnic genome-wide meta-analysis of 35,732 cases and 34,424 controls identifies novel genomic cross-ancestry loci contributing to lung cancer susceptibility" (2020, bioRxiv - Cold Spring Harbor Laboratory)
  • "Abstract IA15: Role of environment in genetic predisposition: Lessons from tobacco studies" (2020, Cancer Prevention Research)

Frequent co-authors in their research include James McKay, Christopher I. Amos, Jinyoung Byun, Yafang Li, and Jun Xia.

The scientist's work has been published across several venues such as Nature Genetics, Journal of Clinical Oncology, npj Precision Oncology, bioRxiv (Cold Spring Harbor Laboratory), and Cancer Prevention Research.

Best Publications

  • Somatic mutations affect key pathways in lung adenocarcinoma

    Li Ding;Gad Getz;David A. Wheeler;Elaine R. Mardis

  • Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

    Christopher I. Amos;Xifeng Wu;Peter Broderick;Ivan P. Gorlov

  • Characterizing the cancer genome in lung adenocarcinoma

    Barbara A. Weir;Barbara A. Weir;Michele S. Woo;Gad Getz;Sven Perner;Sven Perner

  • Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

    James D McKay;Rayjean J Hung;Younghun Han;Xuchen Zong

  • Plasma Levels of Insulin-Like Growth Factor-I and Lung Cancer Risk: a Case-Control Analysis

    He Yu;Margaret R. Spitz;Jehangir Mistry;Jun Gu

  • The PhenX Toolkit: Get the Most From Your Measures

    Carol M. Hamilton;Lisa C. Strader;Joseph G. Pratt;Deborah Maiese

  • Common 5p15.33 and 6p21.33 variants influence lung cancer risk.

    Yufei Wang;Peter Broderick;Emily Webb;Xifeng Wu

  • Modulation of Nucleotide Excision Repair Capacity by XPD Polymorphisms in Lung Cancer Patients

    Margaret R. Spitz;Xifeng Wu;Yunfei Wang;Li E. Wang

  • Repair of Tobacco Carcinogen-Induced DNA Adducts and Lung Cancer Risk: a Molecular Epidemiologic Study

    Qingyi Wei;Lie Cheng;Christopher I. Amos;Li E. Wang

  • A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma.

    Maria Teresa Landi;Nilanjan Chatterjee;Kai Yu;Lynn R. Goldin

  • Telomere dysfunction: a potential cancer predisposition factor.

    Xifeng Wu;Christopher I. Amos;Yong Zhu;Hua Zhao

  • A Risk Model for Prediction of Lung Cancer

    Margaret R. Spitz;Waun Ki Hong;Christopher I. Amos;Xifeng Wu

  • Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

    Yufei Wang;James D McKay;Thorunn Rafnar;Zhaoming Wang

  • Marijuana Use and Increased Risk of Squamous Cell Carcinoma of the Head and Neck

    Zuo Feng Zhang;Hal Morgenstern;Margaret R. Spitz;Donald P. Tashkin

  • Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta

    Heather H. Nelson;John K. Wiencke;David C. Christiani;T. J. Cheng

  • Genetic Susceptibility to Lung Cancer The Role of DNA Damage and Repair

    Margaret R. Spitz;Qingyi Wei;Qiong Dong;Christopher I. Amos

  • Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms.

    Ivan P. Gorlov;Olga Y. Gorlova;Shamil R. Sunyaev;Margaret R. Spitz

  • Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD

    Nancy L. Saccone;Nancy L. Saccone;Robert C Culverhouse;Tae-Hwi Schwantes-An;Dale S. Cannon

  • Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck.

    Erich M. Sturgis;Edward J. Castillo;Lei Li;Rong Zheng

  • Multiple primary cancer in patients with cancer of the head and neck: Second cancer of the head and neck, esophagus, and lung

    Jere T.W. Licciardello;Margaret R. Spitz;Waun Ki Hong

Frequent Co-Authors

Xifeng Wu
Xifeng Wu Zhejiang University
Christopher I. Amos
Christopher I. Amos Baylor College of Medicine
Qingyi Wei
Qingyi Wei Duke University
Waun Ki Hong
Waun Ki Hong The University of Texas MD Anderson Cancer Center
Jian Gu
Jian Gu The University of Texas MD Anderson Cancer Center
Ann G. Schwartz
Ann G. Schwartz Wayne State University
Neil E. Caporaso
Neil E. Caporaso National Institutes of Health
Melissa L. Bondy
Melissa L. Bondy Stanford University
Scott M. Lippman
Scott M. Lippman University of California, San Diego
Maria Teresa Landi
Maria Teresa Landi National Institutes of Health

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