World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
77
Citations
19507
World Ranking
1117
National Ranking
577

Overview

Jian Gu is affiliated with The University of Texas MD Anderson Cancer Center in the United States and has contributed extensively to medical research, particularly in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields including Molecular Biology, Genetics, Cancer Research, Oncology, and Pulmonary and Respiratory Medicine.

Their research touches multiple specialized topics such as Cancer Genomics and Diagnostics, Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Maternal Mental Health During Pregnancy and Postpartum, BRCA Gene Mutations in Cancer, RNA Modifications and Cancer, and Prostate Cancer Treatment and Research.

Jian Gu has published in a range of academic journals with frequent contributions to Cancer Research, Cancers, UNC Libraries, International Journal of Molecular Sciences, and Scientific Reports.

Coauthors who have frequently collaborated with Jian Gu include:

  • Maosheng Huang
  • Montserrat García-Closas
  • Olufunmilayo I. Olopade
  • Da-Tian Bau
  • Guochong Jia

Recent publications featuring Jian Gu's research include:

  • Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF-β signaling in regulatory T cells, 2022, Cell Reports
  • Comparison of clinical characteristics and outcomes of patients with coronavirus disease 2019 at different ages, 2020, Aging
  • Clinical Features of COVID-19 in Patients With Essential Hypertension and the Impacts of Renin-angiotensin-aldosterone System Inhibitors on the Prognosis of COVID-19 Patients, 2020, Hypertension
  • Flumatinib versus Imatinib for Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia: A Phase III, Randomized, Open-label, Multi-center FESTnd Study, 2020, Clinical Cancer Research
  • Emerging mechanisms progress of colorectal cancer liver metastasis, 2022, Frontiers in Endocrinology

Best Publications

  • Erratum: Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer (Nature Genetics (2009) 41 (991-995))

    Xifeng Wu;Yuanqing Ye;Lambertus A. Kiemeney;Patrick Sulem

  • Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

    Christopher I. Amos;Xifeng Wu;Peter Broderick;Ivan P. Gorlov

  • Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

    Yufei Wang;James D McKay;Thorunn Rafnar;Zhaoming Wang

  • MicroRNAs and their isomiRs function cooperatively to target common biological pathways

    Nicole Cloonan;Shivangi Wani;Qinying Xu;Jian Gu

  • Bladder Cancer Predisposition: A Multigenic Approach to DNA-Repair and Cell-Cycle–Control Genes

    Xifeng Wu;Jian Gu;H. Barton Grossman;Christopher I. Amos

  • Antitumor Activity and Bystander Effects of the Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Gene

    Shunsuke Kagawa;Chao He;Jian Gu;Patricia Koch

  • Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk.

    Yuanqing Ye;Kenneth K. Wang;Jian Gu;Hushan Yang

  • Mitochondrial DNA Content: Its Genetic Heritability and Association With Renal Cell Carcinoma

    Jinliang Xing;Meng Chen;Christopher G. Wood;Jie Lin

  • Tumor-specific Transgene Expression from the Human Telomerase Reverse Transcriptase Promoter Enables Targeting of the Therapeutic Effects of the Bax Gene to Cancers

    Jian Gu;Shunsuke Kagawa;Masahiro Takakura;Satoru Kyo

  • Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.

    Yohei Horikawa;Christopher G. Wood;Hushan Yang;Hua Zhao

  • Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer

    Xifeng Wu;Yuanqing Ye;Lambertus A. Kiemeney;Patrick Sulem

  • Prostate Stem Cell Antigen: A Jekyll and Hyde Molecule?

    Norihisa Saeki;Jian Gu;Teruhiko Yoshida;Xifeng Wu

  • Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma.

    James R. Cerhan;Sonja I. Berndt;Joseph Vijai;Hervé Ghesquières

  • Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

    Zhen Dong Xiao;Leng Han;Leng Han;Hyemin Lee;Li Zhuang

  • Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death

    Shunsuke Kagawa;Jian Gu;Tsuyoshi Honda;Timothy J. McDonnell

  • Genetic variants in MicroRNA biosynthesis pathways and binding sites modify ovarian cancer risk, survival, and treatment response.

    Dong Liang;Larissa Alejandra Meyer;David W. Chang;Jie Lin

  • Mosaic loss of chromosome Y is associated with common variation near TCL1A

    Weiyin Zhou;Weiyin Zhou;Mitchell J Machiela;Neal D Freedman;Nathaniel Rothman

  • Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

    Joshua N. Sampson;William A. Wheeler;Meredith Yeager;Orestis Panagiotou

  • Tumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterations.

    Brian B. Tuch;Rebecca R. Laborde;Xing Xu;Jian Gu

  • Genome-wide association study identifies multiple loci associated with bladder cancer risk

    Jonine D. Figueroa;Yuanqing Ye;Afshan Siddiq;Afshan Siddiq;Montserrat Garcia-closas;Montserrat Garcia-closas

Frequent Co-Authors

Xifeng Wu
Xifeng Wu Zhejiang University
Yuanqing Ye
Yuanqing Ye The University of Texas MD Anderson Cancer Center
Colin P. Dinney
Colin P. Dinney The University of Texas MD Anderson Cancer Center
Jack A. Roth
Jack A. Roth The University of Texas MD Anderson Cancer Center
Michelle A.T. Hildebrandt
Michelle A.T. Hildebrandt The University of Texas MD Anderson Cancer Center
Margaret R. Spitz
Margaret R. Spitz Baylor College of Medicine
David W. Chang
David W. Chang University of Chicago
Scott M. Lippman
Scott M. Lippman University of California, San Diego
Stephen J. Chanock
Stephen J. Chanock National Institutes of Health
Jaffer A. Ajani
Jaffer A. Ajani The University of Texas MD Anderson Cancer Center

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