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Medicine

D-Index
92
Citations
40525
World Ranking
11132
National Ranking
5728

Overview

Saraswati Sukumar is affiliated with Johns Hopkins University School of Medicine in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these areas, their work focuses significantly on Molecular Biology, Cancer Research, Oncology, Biomedical Engineering, and Radiology, Nuclear Medicine and Imaging.

The major topics in their studies include Cancer Genomics and Diagnostics, Epigenetics and DNA Methylation, Nanoplatforms for cancer theranostics, Breast Cancer Treatment Studies, Monoclonal and Polyclonal Antibodies Research, Advanced biosensing and bioanalysis techniques, and CRISPR and Genetic Engineering.

Notable recent publications by Saraswati Sukumar include:

  • Targeted nanopore sequencing with Cas9-guided adapter ligation, 2020, Nature Biotechnology
  • Nanoparticle interactions with immune cells dominate tumor retention and induce T cell-mediated tumor suppression in models of breast cancer, 2020, Science Advances
  • HOX genes and the NF-κB pathway: A convergence of developmental biology, inflammation and cancer biology, 2020, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • Multiple roles of HOX proteins in Metastasis: Let me count the ways, 2020, Cancer and Metastasis Reviews
  • DNA methylation markers predict recurrence-free interval in triple-negative breast cancer, 2020, npj Breast Cancer

Saraswati Sukumar has collaborated frequently with several researchers including Mary Jo Fackler, Leslie Cope, Christopher B. Umbricht, Kala Visvanathan, and Guannan Wang.

The scientist has contributed multiple articles to prominent publication venues such as Cancer Research, UNC Libraries, Clinical Epigenetics, npj Breast Cancer, and Oncogene.

Best Publications

  • Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

    Rajnish A. Gupta;Nilay R. Shah;Kevin C. Wang;Jeewon Kim

  • Genomic landscapes of human breast and colorectal cancers

    Laura D. Wood;Williams D. Parsons;Sian Jones;Jimmy Lin

  • Molecular Definition of Breast Tumor Heterogeneity

    Michail Shipitsin;Lauren L. Campbell;Pedram Argani;Stanislawa Weremowicz

  • Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

    Tiffany Hung;Yulei Wang;Michael F. Lin;Michael F. Lin;Ashley K. Koegel

  • Direct mutagenesis of Ha- ras -1 oncogenes by N -nitroso- N -methylurea during initiation of mammary carcinogenesis in rats

    Helmut Zarbl;Saraswati Sukumar;Anne V. Arthur;Dionisio Martin-Zanca

  • Analysis of human transcriptomes

    Victor E Velculescu;Stephen L Madden;Lin Zhang;Alex E Lash

  • The Hox genes and their roles in oncogenesis

    Nilay Shah;Saraswati Sukumar

  • Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H- ras -1 locus by single point mutations

    Saraswati Sukumar;Vicente Notario;Dionisio Martin-Zanca;Mariano Barbacid

  • Compromised HOXA5 function can limit p53 expression in human breast tumours

    Venu Raman;Shelby A. Martensen;David Reisman;Ella Evron

  • Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast

    Scott L. Kominsky;Pedram Argani;Dorian Korz;Ella Evron;Ella Evron

  • High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer

    Anne T. Ferguson;Ella Evron;Christopher B. Umbricht;Tej K. Pandita

  • Molecular links between obesity and breast cancer

    A M Lorincz;S Sukumar

  • DNA methylation regulates MicroRNA expression.

    Liangfeng Han;P. Dane Witmer Witmer;Emily Casey;David Valle

  • Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR

    Ella Evron;William C. Dooley;Christopher B. Umbricht;Dorothy Rosenthal

  • HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs

    H Zhang;H Zhang;C C L Wong;H Wei;D M Gilkes

  • Hypermethylation of 14-3-3 σ (stratifin) is an early event in breast cancer

    Christopher B Umbricht;Ella Evron;Edward Gabrielson;Anne Ferguson

  • Activation of ras oncogenes preceding the onset of neoplasia

    Ramesh Kumar;Saraswati Sukumar;Mariano Barbacid

  • Myeloid Progenitor Cells in the Premetastatic Lung Promote Metastases by Inducing Mesenchymal to Epithelial Transition

    Dingcheng Gao;Natasha Joshi;Hyejin Choi;Seongho Ryu

  • Combining serial analysis of gene expression and array technologies to identify genes differentially expressed in breast cancer.

    Mariana Nacht;Anne T. Ferguson;Wen Zhang;Joseph M. Petroziello

  • Modeling precision treatment of breast cancer

    Anneleen Daemen;Anneleen Daemen;Anneleen Daemen;Obi L Griffith;Obi L Griffith;Obi L Griffith;Laura M Heiser;Laura M Heiser;Nicholas J Wang;Nicholas J Wang

Frequent Co-Authors

Pedram Argani
Pedram Argani Johns Hopkins University
Edward Gabrielson
Edward Gabrielson Johns Hopkins University School of Medicine
Kornelia Polyak
Kornelia Polyak Harvard University
Vered Stearns
Vered Stearns Johns Hopkins University
David L. Huso
David L. Huso Johns Hopkins University
Leslie Cope
Leslie Cope Johns Hopkins University School of Medicine
Antonio C. Wolff
Antonio C. Wolff Johns Hopkins University
Kala Visvanathan
Kala Visvanathan Johns Hopkins University
Tao Zhu
Tao Zhu University of Science and Technology of China
Nancy E. Davidson
Nancy E. Davidson University of Washington

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