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Haruo Sugiyama

Haruo Sugiyama

D-Index & Metrics

Microbiology

D-Index
71
Citations
18302
World Ranking
1844
National Ranking
56

Overview

Haruo Sugiyama is affiliated with Osaka University in Japan and has contributed extensively to research in medicine, immunology, and molecular biology. Their scientific work spans multiple subfields, with a focus on oncology, immunology, and molecular biology, along with areas including pulmonary and respiratory medicine, and radiology, nuclear medicine, and imaging.

Their main research topics include immunotherapy and immune responses, renal and related cancers, CAR-T cell therapy research, cancer immunotherapy and biomarkers, pancreatic and hepatic oncology research, immune cell function and interaction, as well as epigenetics and DNA methylation.

Sugiyama has authored several papers published in notable scientific journals. Some of their recent papers include:

  • Prognostic value of immune factors in the tumor microenvironment of patients with pancreatic ductal adenocarcinoma, 2021, BMC Cancer
  • Dendritic Cell-based Immunotherapy Pulsed With Wilms Tumor 1 Peptide and Mucin 1 as an Adjuvant Therapy for Pancreatic Ductal Adenocarcinoma After Curative Resection: A Phase I/IIa Clinical Trial, 2020, Anticancer Research
  • Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain, 2022, Science Translational Medicine
  • Cellular and Humoral Immune Responses Induced by an HLA Class I-restricted Peptide Cancer Vaccine Targeting WT1 Are Associated With Favorable Clinical Outcomes in Advanced Ovarian Cancer, 2021, Journal of Immunotherapy
  • Regeneration of Tumor-Antigen-Specific Cytotoxic T Lymphocytes from iPSCs Transduced with Exogenous TCR Genes, 2020, Molecular Therapy - Methods & Clinical Development

The frequent co-authors collaborating with Sugiyama include Yoshitaka Oka, Yusuke Oji, Akihiro Tsuboi, Soyoko Morimoto, and Fumihiro Fujiki. These collaborations reflect a network of researchers contributing to related fields.

The scientist's work is frequently published in journals such as Cancer Immunology Immunotherapy, Circulation, Journal for ImmunoTherapy of Cancer, Journal of Hematology & Oncology, and Cancers. The range of venues demonstrates a multidisciplinary approach within biomedical research.

Best Publications

  • Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression

    Yoshihiro Oka;Akihiro Tsuboi;Tetsuya Taguchi;Tadashi Osaki

  • WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia.

    K Inoue;H Sugiyama;H Ogawa;M Nakagawa

  • CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia

    Naoki Hosen;Christopher Y. Park;Naoya Tatsumi;Yusuke Oji

  • Aberrant Overexpression of the Wilms Tumor Gene (WT1) in Human Leukemia

    Kazushi Inoue;Hiroyasu Ogawa;Hiroyasu Ogawa;Yoshiaki Sonoda;Yoshiaki Sonoda;Takafumi Kimura;Takafumi Kimura

  • Induction of complete and molecular remissions in acute myeloid leukemia by Wilms’ tumor 1 antigen-targeted dendritic cell vaccination

    Viggo F. van Tendeloo;Ann Van de Velde;Ann van Driessche;Nathalie Cools

  • Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene (WT1 ) product.

    Yoshihiro Oka;Olga A. Elisseeva;Akihiro Tsuboi;Hiroyasu Ogawa

  • Immunohistochemical detection of WT1 protein in a variety of cancer cells

    Shin-ichi Nakatsuka;Yusuke Oji;Tetsuya Horiuchi;Takayoshi Kanda

  • Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis

    T Yamagami;H Sugiyama;K Inoue;H Ogawa

  • Cancer Immunotherapy Targeting Wilms’ Tumor Gene WT1 Product

    Yoshihiro Oka;Keiko Udaka;Akihiro Tsuboi;Olga A. Elisseeva

  • The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia.

    Hiroyasu Ogawa;Hiroya Tamaki;Kazuhiro Ikegame;Toshihiro Soma

  • Expression of the Wilms' tumor gene WT1 in solid tumors and its involvement in tumor cell growth.

    Yusuke Oji;Hiroyasu Ogawa;Hiroya Tamaki;Yoshihiro Oka

  • Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers

    Yusuke Oji;Shinichiro Miyoshi;Hajime Maeda;Seiji Hayashi

  • Phase II clinical trial of Wilms tumor 1 peptide vaccination for patients with recurrent glioblastoma multiforme.

    Shuichi Izumoto;Akihiro Tsuboi;Yoshihiro Oka;Tsuyoshi Suzuki

  • High expression of Wilms' tumor suppressor gene predicts poor prognosis in breast cancer patients.

    Yasuo Miyoshi;Akiko Ando;Chiyomi Egawa;Tetsuya Taguchi

  • WT1 (Wilms' tumor gene 1): biology and cancer immunotherapy

    Haruo Sugiyama

  • Long-term follow-up of minimal residual disease in leukemia patients by monitoring WT1 (Wilms tumor gene) expression levels

    Kazushi Inoue;Hiroyasu Ogawa;Tamotsu Yamagami;Toshihiro Soma

  • Wilms' tumor gene (WT1) competes with differentiation-inducing signal in hematopoietic progenitor cells

    Kazushi Inoue;Hiroya Tamaki;Hiroyasu Ogawa;Yoshihiro Oka

  • The Wilms' tumor gene WT1 is a good marker for diagnosis of disease progression of myelodysplastic syndromes.

    H. Tamaki;H. Ogawa;K. Ohyashiki;Jh H. Ohyashiki

  • Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia

    Sébastien Anguille;Ann L. Van De Velde;Evelien L. Smits;Viggo F. Van Tendeloo

  • Characterization of Y73, an avian sarcoma virus: a unique transforming gene and its product, a phosphopolyprotein with protein kinase activity.

    Sadaaki Kawai;Mitsuaki Yoshida;Kaoru Segawa;Haruo Sugiyama

Frequent Co-Authors

Yoshihiro Oka
Yoshihiro Oka Osaka University
Yusuke Oji
Yusuke Oji Osaka University
Katsuyuki Aozasa
Katsuyuki Aozasa Osaka University
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Atsushi Kumanogoh
Atsushi Kumanogoh Osaka University
Satoshi Morita
Satoshi Morita Kyoto University
Yuzuru Kanakura
Yuzuru Kanakura Osaka University
Eiichi Morii
Eiichi Morii Osaka University
Toshihisa Komori
Toshihisa Komori Nagasaki University
Masaki Yasukawa
Masaki Yasukawa Ehime University

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