World's Best Scientists 2026 revealed!
Denis L. J. Lafontaine

Denis L. J. Lafontaine

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
14432
World Ranking
11863
National Ranking
217

Overview

Denis L. J. Lafontaine is a researcher affiliated with Université Libre de Bruxelles in Belgium. The primary field of study is Biochemistry, Genetics and Molecular Biology, with a specific focus on Molecular Biology as the predominant subfield. Their work also spans Cancer Research, Genetics, Plant Science, and Biomedical Engineering.

The research topics covered by Lafontaine include:

  • RNA modifications and cancer
  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • Cancer-related molecular mechanisms research
  • Cancer-related gene regulation
  • Genomics and Chromatin Dynamics
  • Molecular Biology Techniques and Applications

Lafontaine's publication record includes contributions to multiple well-known scientific journals and venues. The most frequent publication outlets are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Molecular Cell
  • RNA Biology
  • Zenodo (CERN European Organization for Nuclear Research)

Among recent papers authored or co-authored by Lafontaine are:

  • The nucleolus as a multiphase liquid condensate, 2020, Nature Reviews Molecular Cell Biology
  • Hi-C 3.0: Improved Protocol for Genome-Wide Chromosome Conformation Capture, 2021, Current Protocols

Other relevant recent publications closely associated with Lafontaine's network include papers such as Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics (2021, Nature Genetics), HydraPsiSeq: a method for systematic and quantitative mapping of pseudouridines in RNA (2020, Nucleic Acids Research), and The 18S ribosomal RNA m6A methyltransferase Mettl5 is required for normal walking behavior in Drosophila (2020, EMBO Reports).

Collaboration is a notable aspect of Lafontaine's research profile, with frequent co-authors including:

  • Ludivine Wacheul
  • Christiane Zorbas
  • Felix G.M. Ernst
  • Christoph Dieterich
  • Sunny Sharma

Best Publications

  • The nucleolus as a multiphase liquid condensate

    Denis L. J. Lafontaine;Joshua A. Riback;Rümeyza Bascetin;Clifford P. Brangwynne

  • A new system for naming ribosomal proteins

    Nenad Ban;Roland Beckmann;Jamie H D Cate;Jonathan D Dinman

  • Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

    Katherine E. Sloan;Ahmed S. Warda;Sunny Sharma;Karl-Dieter Entian

  • Melanoma addiction to the long non-coding RNA SAMMSON.

    Eleonora Leucci;Roberto Vendramin;Marco Spinazzi;Patrick Laurette

  • The Complexity of Human Ribosome Biogenesis Revealed by Systematic Nucleolar Screening of Pre-rRNA Processing Factors

    Lionel Tafforeau;Christiane Zorbas;Jean-Louis Langhendries;Sahra-Taylor Mullineux

  • The box H+ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase

    Denis L.J. Lafontaine;Cécile Bousquet-Antonelli;Yves Henry;Michèle Caizergues-Ferrer

  • The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.

    Nhan van Tran;Felix G M Ernst;Ben R Hawley;Christiane Zorbas

  • The cell proliferation antigen Ki-67 organises heterochromatin

    Michal Sobecki;Michal Sobecki;Karim Mrouj;Karim Mrouj;Alain Camasses;Alain Camasses;Nikolaos Parisis;Nikolaos Parisis

  • The function and synthesis of Ribosomes

    Denis L.J. Lafontaine;David Tollervey

  • Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments.

    Céline Verheggen;Denis L.J. Lafontaine;Dmitry Samarsky;John Mouaikel

  • The nucleolus: structure/function relationship in RNA metabolism

    Danièle Hernandez-Verdun;Pascal Roussel;Marc Thiry;Valentina Sirri

  • Noncoding RNAs in eukaryotic ribosome biogenesis and function

    Denis L J Lafontaine

  • Birth of a nucleolus: the evolution of nucleolar compartments

    Marc Thiry;Denis L.J. Lafontaine

  • Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1

    Sunny Sharma;Jean-Louis Langhendries;Peter Watzinger;Peter Kötter

  • Mapping the cleavage sites on mammalian pre-rRNAs: Where do we stand?

    Sahra-Taylor Mullineux;Denis L.J. Lafontaine

  • The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.

    Denis Lafontaine;Jean Vandenhaute;D Tollervey

  • Pseudouridine Mapping in the Saccharomyces cerevisiae Spliceosomal U Small Nuclear RNAs (snRNAs) Reveals that Pseudouridine Synthase Pus1p Exhibits a Dual Substrate Specificity for U2 snRNA and tRNA

    Séverine Massenet;Yuri Motorin;Denis L. J. Lafontaine;Eduard C. Hurt

  • Birth of the snoRNPs: the evolution of the modification-guide snoRNAs

    Denis L.J Lafontaine;David Tollervey

  • THE DIM1 GENE RESPONSIBLE FOR THE CONSERVED M62AM62A DIMETHYLATION IN THE 3'-TERMINAL LOOP OF 18 S RRNA IS ESSENTIAL IN YEAST

    Denis Lafontaine;Jean Delcour;Anne-Lise Glasser;Jean Desgres

  • ‘View From A Bridge’: A New Perspective on Eukaryotic rRNA Base Modification

    Sunny Sharma;Denis L.J. Lafontaine

Frequent Co-Authors

David Tollervey
David Tollervey University of Edinburgh
Karl-Dieter Entian
Karl-Dieter Entian Goethe University Frankfurt
Alexandre David
Alexandre David Aalborg University
Marc Thiry
Marc Thiry University of Liège
Johannes Grillari
Johannes Grillari BOKU University
Mark Helm
Mark Helm Johannes Gutenberg University of Mainz
robert feil
robert feil Centre national de la recherche scientifique, CNRS
Clifford P. Brangwynne
Clifford P. Brangwynne Princeton University
Michèle Caizergues-Ferrer
Michèle Caizergues-Ferrer Centre national de la recherche scientifique, CNRS
Yanick J. Crow
Yanick J. Crow Université Paris Cité

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Denis L. J. Lafontaine

Trending Scientists

Recently Published Articles