World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
78
Citations
25247
World Ranking
17949
National Ranking
8952

Overview

David L. Huso was affiliated with Johns Hopkins University in the United States. Their research contributions spanned multiple areas within medicine and molecular biology, with a focus on oncology, infectious diseases, surgery, endocrinology, and molecular biology.

The scientist's work involved several key topics, including:

  • Clostridium difficile and Clostridium perfringens research
  • Helicobacter pylori-related gastroenterology studies
  • Escherichia coli research studies
  • Epigenetics and DNA methylation
  • Pancreatic and hepatic oncology research
  • Cancer cells and metastasis

Among their published papers, two notable examples are:

  • "G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis," published in 2021 in Communications Biology
  • "Abstract 297: HMGA1 induces FGF-19 to foster tumor-stromal cell crosstalk and drive tumor progression in pancreatic ductal adenocarcinoma," published in 2020 in Cancer Research

Their frequent co-authors included:

  • Annemarie Boleij
  • Payam Fathi
  • W. Brian Dalton
  • Ben Park
  • Xinqun Wu

Regarding publication venues, their work appeared predominantly in:

  • Communications Biology
  • Cancer Research

Their main fields of study encompassed:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, subfields of focus included oncology, infectious diseases, surgery, endocrinology, and molecular biology, reflecting a multidisciplinary approach to health sciences and cancer research. The recorded citations indicate engagement with ongoing scientific discourse, particularly in cancer biology and gastrointestinal microbiology.

Best Publications

  • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

    Shaoguang Wu;Ki Jong Rhee;Ki Jong Rhee;Ki Jong Rhee;Emilia Albesiano;Shervin Rabizadeh

  • Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.

    Jennifer P. Habashi;Daniel P. Judge;Tammy M. Holm;Ronald D. Cohn

  • Mutant PIK3CA promotes cell growth and invasion of human cancer cells

    Yardena Samuels;Luis A. Diaz;Oleg Schmidt-Kittler;Jordan M. Cummins

  • Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

    Christine M. Dejea;Payam Fathi;John M. Craig;Annemarie Boleij;Annemarie Boleij

  • Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α

    Aimee Y. Yu;Larissa A. Shimoda;Narayan V. Iyer;David L. Huso

  • Combination bacteriolytic therapy for the treatment of experimental tumors

    Long H. Dang;Chetan Bettegowda;David L. Huso;Kenneth W. Kinzler

  • Nitric oxide synthase in cardiac sarcoplasmic reticulum

    Kai Y. Xu;David L. Huso;Ted M. Dawson;David S. Bredt

  • Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

    Liam Chung;Erik Thiele Orberg;Abby L. Geis;June L. Chan

  • Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis.

    Andrew C. Goodwin;Christina E. Destefano Shields;Shaoguang Wu;David L. Huso

  • P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

    Munekazu Yamakuchi;Craig D. Lotterman;Clare Bao;Ralph H. Hruban

  • Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome

    Daniel P. Judge;Nancy J. Biery;Douglas R. Keene;Jessica Geubtner

  • A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

    Klaus Piontek;Luis F Menezes;Miguel A Garcia-Gonzalez;David L Huso

  • An HIV-1 transgenic rat that develops HIV-related pathology and immunologic dysfunction

    W. Reid;M. Sadowska;F. Denaro;S. Rao

  • Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses

    Nicholas J. Roberts;Linping Zhang;Filip Janku;Amanda Collins

  • Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity

    Ling Yang Hao;Mary Armanios;Margaret A. Strong;Baktiar Karim

  • Bacteriolytic therapy can generate a potent immune response against experimental tumors

    Nishant Agrawal;Chetan Bettegowda;Ian Cheong;Jean Francois Geschwind

  • Circulating transforming growth factor-beta in Marfan syndrome.

    Peter Matt;Florian Schoenhoff;Jennifer Habashi;Tammy Holm

  • Induction of Persistent Colitis by a Human Commensal, Enterotoxigenic Bacteroides fragilis, in Wild-Type C57BL/6 Mice

    Ki Jong Rhee;Shaoguang Wu;Xinqun Wu;David L. Huso

  • Endothelial arginase II: a novel target for the treatment of atherosclerosis.

    Sungwoo Ryoo;Gaurav Gupta;Alexandre Benjo;Hyun Kyo Lim;Hyun Kyo Lim

  • Angiotensin II–dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis

    Elena M. Gallo;David C. Loch;Jennifer P. Habashi;Juan F. Calderon

Frequent Co-Authors

Harry C. Dietz
Harry C. Dietz Johns Hopkins University School of Medicine
Donald Small
Donald Small Johns Hopkins University
Franck Housseau
Franck Housseau Johns Hopkins University School of Medicine
Bert Vogelstein
Bert Vogelstein Johns Hopkins University
Kenneth W. Kinzler
Kenneth W. Kinzler Johns Hopkins University
Saraswati Sukumar
Saraswati Sukumar Johns Hopkins University School of Medicine
Jennifer E. Van Eyk
Jennifer E. Van Eyk Cedars-Sinai Medical Center
Drew M. Pardoll
Drew M. Pardoll Johns Hopkins University School of Medicine
George Sgouros
George Sgouros Johns Hopkins University
Daniel P. Judge
Daniel P. Judge Medical University of South Carolina

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