Johns Hopkins University
His main research concerns Cancer research, Microbiology, Carcinogenesis, Molecular biology and Bacteroides fragilis. His Cancer research study combines topics in areas such as Human tumor, Heterologous, Immunology, Germ cell and Telomere. His work deals with themes such as Bacteriolytic Therapy, Anaerobic bacteria, Bacteria and Immune system, which intersect with Microbiology.
His work carried out in the field of Carcinogenesis brings together such families of science as Inflammation, Proinflammatory cytokine, Catabolism, Polyamine Catabolism and Pathology. His Molecular biology research is multidisciplinary, incorporating elements of Nitric oxide synthase, Cardiac muscle, Mutation, Mutant and Gene targeting. His Bacteroides fragilis research is multidisciplinary, incorporating perspectives in Receptor, Colitis, DNA damage and Diarrhea.
David L. Huso mostly deals with Cancer research, Carcinogenesis, Internal medicine, Immunology and Cancer. The concepts of his Cancer research study are interwoven with issues in Cancer stem cell, Stem cell, Pathology, Leukemia and Colorectal cancer. His research in Carcinogenesis intersects with topics in Wnt signaling pathway, Colitis, Bacteroides fragilis, Transcription factor and Tumor progression.
His Bacteroides fragilis research is multidisciplinary, relying on both Inflammation and Cytokine. His Internal medicine study incorporates themes from Endocrinology and Oncology. In the field of Immunology, his study on Immune system and Bone marrow overlaps with subjects such as Population.
Cancer research, Carcinogenesis, Internal medicine, Bacteroides fragilis and Stem cell are his primary areas of study. His Cancer research study combines topics from a wide range of disciplines, such as Cancer stem cell, Breast cancer and Cancer. David L. Huso has included themes like Chemokine, CXCL1, Transcription factor and Bacteria in his Carcinogenesis study.
His research integrates issues of Nuclear receptor, Endocrinology and Oncology in his study of Internal medicine. His work in Endocrinology addresses issues such as Haploinsufficiency, which are connected to fields such as Genetically modified mouse, Angiotensin II, Loeys–Dietz syndrome and Losartan. His study in Bacteroides fragilis is interdisciplinary in nature, drawing from both Colitis, Inflammation, Secretion, Microbiology and Colorectal cancer.
David L. Huso spends much of his time researching Immunology, Carcinogenesis, Bacteroides fragilis, Cancer research and Inflammation. His studies in Immunology integrate themes in fields like Chondrosarcoma, STAT5, Matrix metalloproteinase and Cell biology. David L. Huso combines subjects such as Colorectal cancer, Colon Adenoma, Colitis and Escherichia coli with his study of Carcinogenesis.
His study ties his expertise on Microbiology together with the subject of Bacteroides fragilis. His work often combines Cancer research and HDAC6 studies. His Inflammation research includes themes of Acquired immune system and Immune system.
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Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
Jennifer P. Habashi;Daniel P. Judge;Tammy M. Holm;Ronald D. Cohn.
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
Shaoguang Wu;Ki Jong Rhee;Ki Jong Rhee;Ki Jong Rhee;Emilia Albesiano;Shervin Rabizadeh.
Nature Medicine (2009)
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
Yardena Samuels;Luis A. Diaz;Oleg Schmidt-Kittler;Jordan M. Cummins.
Cancer Cell (2005)
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
Aimee Y. Yu;Larissa A. Shimoda;Narayan V. Iyer;David L. Huso.
Journal of Clinical Investigation (1999)
Nitric oxide synthase in cardiac sarcoplasmic reticulum
Kai Y. Xu;David L. Huso;Ted M. Dawson;David S. Bredt.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
Christine M. Dejea;Payam Fathi;John M. Craig;Annemarie Boleij;Annemarie Boleij.
Combination bacteriolytic therapy for the treatment of experimental tumors
Long H. Dang;Chetan Bettegowda;David L. Huso;Kenneth W. Kinzler.
Proceedings of the National Academy of Sciences of the United States of America (2001)
P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
Munekazu Yamakuchi;Craig D. Lotterman;Clare Bao;Ralph H. Hruban.
Proceedings of the National Academy of Sciences of the United States of America (2010)
Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome
Daniel P. Judge;Nancy J. Biery;Douglas R. Keene;Jessica Geubtner.
Journal of Clinical Investigation (2004)
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis.
Andrew C. Goodwin;Christina E. Destefano Shields;Shaoguang Wu;David L. Huso.
Proceedings of the National Academy of Sciences of the United States of America (2011)
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