D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 60 Citations 14,718 121 World Ranking 7789 National Ranking 3549

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

Gregory G. Germino spends much of his time researching PKD1, Autosomal dominant polycystic kidney disease, Cell biology, Polycystic kidney disease and Genetics. His work carried out in the field of PKD1 brings together such families of science as Apoptosis, Cancer research and Gene product. In his study, Endocrinology is strongly linked to Sirolimus, which falls under the umbrella field of Cancer research.

His Autosomal dominant polycystic kidney disease study deals with Cystic kidney intersecting with In utero, Regulation of gene expression, Kidney cysts and Physiology. His studies in Cell biology integrate themes in fields like Zebrafish, Cell cycle and Cell growth. His Polycystic kidney disease research is multidisciplinary, incorporating perspectives in TRPV4, Ion channel, Mechanosensitive channels, Calcium in biology and Molecular biology.

His most cited work include:

  • Multiple-laboratory comparison of microarray platforms (784 citations)
  • Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents (692 citations)
  • The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease. (641 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in PKD1, Polycystic kidney disease, Autosomal dominant polycystic kidney disease, Genetics and Cell biology. Gregory G. Germino interconnects Cancer research, Gene product and Allele in the investigation of issues within PKD1. His Polycystic kidney disease study combines topics from a wide range of disciplines, such as Molecular biology and Bioinformatics.

Gregory G. Germino has researched Autosomal dominant polycystic kidney disease in several fields, including Cystic kidney and Kidney disease. His research in Cell biology intersects with topics in Cell cycle and Kidney development. His work deals with themes such as Polycystin 2 and Cleavage, Biochemistry, which intersect with Polycystin-1.

He most often published in these fields:

  • PKD1 (45.31%)
  • Polycystic kidney disease (43.75%)
  • Autosomal dominant polycystic kidney disease (36.72%)

What were the highlights of his more recent work (between 2013-2021)?

  • Polycystic kidney disease (43.75%)
  • PKD1 (45.31%)
  • Autosomal dominant polycystic kidney disease (36.72%)

In recent papers he was focusing on the following fields of study:

Gregory G. Germino mainly focuses on Polycystic kidney disease, PKD1, Autosomal dominant polycystic kidney disease, Cell biology and Internal medicine. His Polycystic kidney disease research incorporates themes from Kidney disease, Computational biology, Gerontology and Bioinformatics. His Autosomal dominant polycystic kidney disease study is concerned with the larger field of Cyst.

His Cell biology research incorporates elements of Phenotype, Cystic kidney and Kidney metabolism. The Internal medicine study which covers Endocrinology that intersects with Cancer research, Haploinsufficiency, Kidney development and Cell migration. His Cilium research is included under the broader classification of Genetics.

Between 2013 and 2021, his most popular works were:

  • Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism (74 citations)
  • Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease (69 citations)
  • Polycystin Signaling Is Required for Directed Endothelial Cell Migration and Lymphatic Development (55 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

Cell biology, PKD1, Phenotype, Autosomal dominant polycystic kidney disease and Cilium are his primary areas of study. Gregory G. Germino has included themes like Polycystin complex, Ciliopathies, Kidney metabolism and Mature Centriole in his Cell biology study. PKD1 is a subfield of Polycystic kidney disease that he studies.

The study incorporates disciplines such as Cyst, Lipid metabolism and Lipidomics in addition to Polycystic kidney disease. Gregory G. Germino is investigating Endocrinology and Internal medicine as part of his examination of Autosomal dominant polycystic kidney disease. He combines subjects such as Transport protein, Cystic kidney, Wnt signaling pathway, Centriole and Centrosome with his study of Cilium.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Multiple-laboratory comparison of microarray platforms

Rafael A Irizarry;Daniel Warren;Forrest Spencer;Irene F Kim.
Nature Methods (2005)

1054 Citations

The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.

Jonathan M. Shillingford;Noel S. Murcia;Claire H. Larson;Seng Hui Low.
Proceedings of the National Academy of Sciences of the United States of America (2006)

887 Citations

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

Kazushige Hanaoka;Feng Qian;Alessandra Boletta;Anil K. Bhunia.
Nature (2000)

887 Citations

PKD1 interacts with PKD2 through a probable coiled-coil domain

Qian F;Germino Fj;Cai Y;Zhang X.
Nature Genetics (1997)

746 Citations

The Molecular Basis of Focal Cyst Formation in Human Autosomal Dominant Polycystic Kidney Disease Type I

Feng Qian;Terry J Watnick;Luiz F Onuchic;Gregory G Germino.
Cell (1996)

677 Citations

PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats

Luiz F. Onuchic;Laszlo Furu;Yasuyuki Nagasawa;Xiaoying Hou.
American Journal of Human Genetics (2002)

602 Citations

PKD1 Induces p21waf1 and Regulation of the Cell Cycle via Direct Activation of the JAK-STAT Signaling Pathway in a Process Requiring PKD2

Anil Kumar Bhunia;Klaus Piontek;Alessandra Boletta;Lijuan Liu.
Cell (2002)

505 Citations

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

Klaus Piontek;Luis F Menezes;Miguel A Garcia-Gonzalez;David L Huso.
Nature Medicine (2007)

388 Citations

TRPP2 and TRPV4 form a polymodal sensory channel complex

Michael Köttgen;Björn Buchholz;Miguel A. García-González;Fruzsina Kotsis.
Journal of Cell Biology (2008)

378 Citations

Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations

Feng Qian;Alessandra Boletta;Anil K. Bhunia;Hangxue Xu.
Proceedings of the National Academy of Sciences of the United States of America (2002)

336 Citations

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