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William B. Guggino

D-Index & Metrics

Biology and Biochemistry

D-Index
102
Citations
40431
World Ranking
1357
National Ranking
785

William B. Guggino publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where William B. Guggino sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 346 publications — 85th percentile

85% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

William B. Guggino D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where William B. Guggino sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 102 D-Index — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

William B. Guggino is affiliated with Johns Hopkins University in the United States, focusing primarily on research within medicine and biochemistry, genetics, and molecular biology. Their research spans multiple subfields, including pulmonary and respiratory medicine, genetics, molecular biology, epidemiology, and nephrology.

The scientist has contributed to topics centered on cystic fibrosis research advances, virus-based gene therapy research, respiratory viral infections research, energy harvesting in wireless networks, neonatal respiratory health research, genetic and kidney cyst diseases, and chronic kidney disease and diabetes.

Recent publications by William B. Guggino include:

  • Gene Therapy for Cystic Fibrosis Paved the Way for the Use of Adeno-Associated Virus in Gene Therapy, 2020, Human Gene Therapy
  • Transduction of Surface and Basal Cells in Rhesus Macaque Lung Following Repeat Dosing with AAV1CFTR, 2020, Human Gene Therapy

Other notable papers related to their frequent collaborators or fields of study include:

  • Megalin-mediated albumin endocytosis in renal proximal tubules is involved in the antiproteinuric effect of angiotensin II type 1 receptor blocker in a subclinical acute kidney injury animal model, 2021, Biochimica et Biophysica Acta (BBA) - General Subjects
  • The Mitochondrial Ca2+ import complex is altered in ADPKD, 2021, Cell Calcium
  • Transduction of Ferret Surface and Basal Cells of Airways, Lung, Liver, and Pancreas via Intratracheal or Intravenous Delivery of Adeno-Associated Virus 1 or 6, 2023, Human Gene Therapy

William B. Guggino frequently collaborates with several researchers, including Liudmila Cebotaru, Murali K. Yanda, Cristian Ciobanu, Vartika Tomar, and Cristina V. Cebotaru.

Their publications have appeared predominantly in the following venues:

  • Human Gene Therapy
  • UNC Libraries
  • Journal of Cystic Fibrosis
  • Biochimica et Biophysica Acta (BBA) - General Subjects
  • Cell Calcium

Best Publications

  • Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein.

    Gregory M. Preston;Tiziana Piazza Carroll;William B. Guggino;Peter Agre

  • In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

    Melissa A. Rosenfeld;Kunihiko Yoshimura;Bruce C. Trapnell;Koichi Yoneyama

  • Aquaporin CHIP: the archetypal molecular water channel

    P. Agre;G. M. Preston;B. L. Smith;Jin Sup Jung

  • Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance

    Jin Sup Jung;Ratan V. Bhat;Gregory M. Preston;William B. Guggino

  • Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

    Kazushige Hanaoka;Feng Qian;Alessandra Boletta;Anil K. Bhunia

  • Molecular structure of the water channel through aquaporin CHIP. The hourglass model.

    Jin Sup Jung;G. M. Preston;B. L. Smith;W. B. Guggino

  • CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP.

    Erik M. Schwiebert;Marie E. Egan;Tae Ho Hwang;Stephanie B. Fulmer

  • Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

    Owen M. Woodward;Anna Köttgen;Josef Coresh;Eric Boerwinkle

  • Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.

    Terence R. Flotte;Sandra A. Afione;Carol Conrad;Sharon A. McGrath

  • The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel.

    G. M. Preston;Jin Sup Jung;W. B. Guggino;P. Agre

  • CHIP28 water channels are localized in constitutively water-permeable segments of the nephron.

    S Nielsen;B L Smith;E I Christensen;M A Knepper

  • Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.

    G R Cutting;L Lu;B F O'Hara;L M Kasch

  • Molecular Characterization of a Broad Selectivity Neutral Solute Channel

    Hiroyasu Tsukaguchi;Chairat Shayakul;Urs V. Berger;Bryan Mackenzie

  • CFTR Is a Conductance Regulator as well as a Chloride Channel

    Erik M. Schwiebert;Dale J. Benos;Marie E. Egan;Monroe Jack Stutts

  • From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.

    Gudio Veit;Radu G. Avramescu;Annette N. Chiang;Scott A. Houck

  • New insights into cystic fibrosis: molecular switches that regulate CFTR.

    William B. Guggino;Bruce A. Stanton

  • MOLECULAR CLONING AND CHARACTERIZATION OF AN AQUAPORIN CDNA FROM SALIVARY,LACRIMAL, AND RESPIRATORY TISSUES

    Surabhi Raina;Gregory M. Preston;William B. Guggino;Peter Agre

  • Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR

    Marie Egan;Terence Flotte;Terence Flotte;Sandra Afione;Rikki Solow

  • Immunocytochemical localization of the cystic fibrosis gene product CFTR.

    Isabelle Crawford;Peter C. Maloney;Pamela L. Zeitlin;William B. Guggino

  • Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

    Hal A Lewis;Sean G Buchanan;Stephen K Burley;Kris Conners

Frequent Co-Authors

Erik M. Schwiebert
Erik M. Schwiebert University of Alabama at Birmingham
Garry R. Cutting
Garry R. Cutting Johns Hopkins University School of Medicine
Terence R. Flotte
Terence R. Flotte University of Massachusetts Chan Medical School
Pamela L. Zeitlin
Pamela L. Zeitlin National Jewish Health
Olivier Devuyst
Olivier Devuyst University of Zurich
Peter Agre
Peter Agre Johns Hopkins University
Harvey B. Pollard
Harvey B. Pollard Uniformed Services University of the Health Sciences
Barrie J. Carter
Barrie J. Carter National Institutes of Health
Pierre J. Courtoy
Pierre J. Courtoy Université Catholique de Louvain
Min Li
Min Li Chinese Academy of Sciences

External Links

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Best Scientists Citing William B. Guggino

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Alan S. Verkman

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Publications: 91

Terence R. Flotte

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Publications: 91

Richard C. Boucher

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University of North Carolina at Chapel Hill

Publications: 84

James M. Wilson

James M. Wilson

University of Pennsylvania

Publications: 83

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Publications: 73

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Publications: 55

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