William B. Guggino

Overview

Best Publications

• Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein.

  Gregory M. Preston;Tiziana Piazza Carroll;William B. Guggino;Peter Agre

  2640
  Citations

• In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

  Melissa A. Rosenfeld;Kunihiko Yoshimura;Bruce C. Trapnell;Koichi Yoneyama

  1283
  Citations

• Aquaporin CHIP: the archetypal molecular water channel

  P. Agre;G. M. Preston;B. L. Smith;Jin Sup Jung

  1065
  Citations

• Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance

  Jin Sup Jung;Ratan V. Bhat;Gregory M. Preston;William B. Guggino

  930
  Citations

• Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

  Kazushige Hanaoka;Feng Qian;Alessandra Boletta;Anil K. Bhunia

  920
  Citations

• Molecular structure of the water channel through aquaporin CHIP. The hourglass model.

  Jin Sup Jung;G. M. Preston;B. L. Smith;W. B. Guggino

  844
  Citations

• CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP.

  Erik M. Schwiebert;Marie E. Egan;Tae Ho Hwang;Stephanie B. Fulmer

  785
  Citations

• Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

  Owen M. Woodward;Anna Köttgen;Josef Coresh;Eric Boerwinkle

  770
  Citations

• Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.

  Terence R. Flotte;Sandra A. Afione;Carol Conrad;Sharon A. McGrath

  724
  Citations

• The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel.

  G. M. Preston;Jin Sup Jung;W. B. Guggino;P. Agre

  711
  Citations

• CHIP28 water channels are localized in constitutively water-permeable segments of the nephron.

  S Nielsen;B L Smith;E I Christensen;M A Knepper

  630
  Citations

• Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.

  G R Cutting;L Lu;B F O'Hara;L M Kasch

  600
  Citations

• Molecular Characterization of a Broad Selectivity Neutral Solute Channel

  Hiroyasu Tsukaguchi;Chairat Shayakul;Urs V. Berger;Bryan Mackenzie

  569
  Citations

• CFTR Is a Conductance Regulator as well as a Chloride Channel

  Erik M. Schwiebert;Dale J. Benos;Marie E. Egan;Monroe Jack Stutts

  564
  Citations

• From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.

  Gudio Veit;Radu G. Avramescu;Annette N. Chiang;Scott A. Houck

  559
  Citations

• New insights into cystic fibrosis: molecular switches that regulate CFTR.

  William B. Guggino;Bruce A. Stanton

  546
  Citations

• MOLECULAR CLONING AND CHARACTERIZATION OF AN AQUAPORIN CDNA FROM SALIVARY,LACRIMAL, AND RESPIRATORY TISSUES

  Surabhi Raina;Gregory M. Preston;William B. Guggino;Peter Agre

  516
  Citations

• Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR

  Marie Egan;Terence Flotte;Terence Flotte;Sandra Afione;Rikki Solow

  516
  Citations

• Immunocytochemical localization of the cystic fibrosis gene product CFTR.

  Isabelle Crawford;Peter C. Maloney;Pamela L. Zeitlin;William B. Guggino

  507
  Citations

• Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

  Hal A Lewis;Sean G Buchanan;Stephen K Burley;Kris Conners

  485
  Citations