John R. Riordan

Research.com Recognitions

• 1990 - Canada Gairdner International Award

Overview

Best Publications

• Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

  John R. Riordan;Johanna M. Rommens;Bat Sheva Kerem;N. O.A. Alon

  9251
  Citations

• Identification of the cystic fibrosis gene: Chromosome walking and jumping

  Johanna M. Rommens;Michael C. Iannuzzi;Bat Sheva Kerem;Mitchell L. Drumm

  4279
  Citations

• Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

  Timothy J. Jensen;Melinda A. Loo;Steven Pind;David B. Williams

  1306
  Citations

• Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines.

  Norbert Kartner;John R. Riordan;Victor Ling

  1292
  Citations

• Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)

  Christine E. Bear;Canhui Li;Norbert Kartner;Robert J. Bridges

  1167
  Citations

• Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines.

  John R. Riordan;Kathryn Deuchars;Norbert Kartner;Noa Alon

  1052
  Citations

• Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis

  Xiaodong Wang;John Venable;Paul LaPointe;Darren M. Hutt

  691
  Citations

• Genomic DNA sequence of the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

  Julian Zielenski;Richard Rozmahel;Dominique Bozon;Bat sheva Kerem

  687
  Citations

• Phosphorylation-regulated Cl- channel in CHO cells stably expressing the cystic fibrosis gene.

  Joseph A. Tabcharani;Xiu-Bao D Chang;John R. Riordan;John W. Hanrahan

  669
  Citations

• Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance

  Norbert Kartner;John W. Hanrahan;Tim J. Jensen;A. Leonard Naismith

  604
  Citations

• Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene.

  B S Kerem;J Zielenski;D Markiewicz;D Bozon

  564
  Citations

• The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

  Kazumitsu Ueda;Marilyn M. Cornwell;Michael M. Gottesman;Ira Pastan

  556
  Citations

• Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome.

  Melinda A. Loo;Timothy J. Jensen;Liying Cui;Yue Xian Hou

  527
  Citations

• Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP.

  Gergely L. Lukacs;Abdalla Mohamed;Norbert Kartner;Xu Bao Chang

  521
  Citations

• Participation of the endoplasmic reticulum chaperone calnexin (p88,IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator

  Steven Pind;John R. Riordan;David B. Williams

  517
  Citations

• Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability.

  J R Riordan;V Ling

  502
  Citations

• Phenylalanine-508 mediates a cytoplasmic–membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

  Adrian W R Serohijos;Tamás Hegedus;Andrei A. Aleksandrov;Lihua He

  446
  Citations

• Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

  Xiu Bao Chang;Joseph A. Tabcharani;Yue Xian Hou;Timothy J. Jensen

  374
  Citations

• The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

  Gergely L. Lukacs;Xiu Bao Chang;Christine Bear;Norbert Kartner

  362
  Citations

• Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA

  John R Riordan

  15
  Citations