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D-Index & Metrics

Molecular Biology

D-Index
79
Citations
23584
World Ranking
1035
National Ranking
545

Overview

Michael B. O'Connor is affiliated with the University of Minnesota in the United States and conducts research primarily in the field of Biochemistry, Genetics and Molecular Biology. Their work covers multiple subfields including Molecular Biology, Cellular and Molecular Neuroscience, Genetics, Immunology, and Ecology, Evolution, Behavior and Systematics.

Their research has focused on several key topics, such as Neurobiology and Insect Physiology Research, Developmental Biology and Gene Regulation, Genetics, Aging, and Longevity in Model Organisms, Physiological and Biochemical Adaptations, Muscle Physiology and Disorders, Invertebrate Immune Response Mechanisms, and TGF-β Signaling in Diseases.

Michael B. O'Connor has published in a variety of venues, frequently contributing to:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Genetics
  • PubMed

Notable recent publications include:

  • Control of the insect metamorphic transition by ecdysteroid production and secretion, 2020, Current Opinion in Insect Science
  • Engineering multiple species-like genetic incompatibilities in insects, 2020, Nature Communications
  • Coordination among multiple receptor tyrosine kinase signals controls Drosophila developmental timing and body size, 2021, Cell Reports
  • The Role of Muscle in Insect Energy Homeostasis, 2020, Frontiers in Physiology
  • Proliferative stem cells maintain quiescence of their niche by secreting the Activin inhibitor Follistatin, 2021, Developmental Cell

Frequent collaborators in Michael B. O'Connor's research include:

  • Aidan J. Peterson
  • MaryJane Shimell
  • Heidi Bretscher
  • Stuart J. Newfeld

Best Publications

  • Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

    Jürg Müller;Craig M. Hart;Nicole J. Francis;Marcus L. Vargas

  • MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways

    Pamela A Hoodless;Theo Haerry;Shirin Abdollah;Mark Stapleton

  • Ecdysone Control of Developmental Transitions: Lessons from Drosophila Research

    Naoki Yamanaka;Kim F Rewitz;Michael B O'Connor

  • Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone

    Anna Petryk;James T. Warren;James T. Warren;Guillermo Marqués;Guillermo Marqués;Michael P. Jarcho

  • Prothoracicotropic Hormone Regulates Developmental Timing and Body Size in Drosophila

    Zofeyah McBrayer;Hajime Ono;Mary Jane Shimell;Jean Philippe Parvy

  • The BMP homolog Gbb provides a retrograde signal that regulates synaptic growth at the Drosophila neuromuscular junction.

    Brian D McCabe;Guillermo Marqués;A.Pejmun Haghighi;Richard D Fetter

  • Production of a DPP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins

    Guillermo Marqués;Michéle Musacchio;Mary Jane Shimell;Katrin Wünnenberg-Stapleton

  • Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila

    Ted J. Brummel;Vern Twombly;Guillermo Marqués;Jeffrey L. Wrana

  • Elements of the Drosophila bithorax complex that mediate repression by Polycomb group products.

    Jeffrey Simon;Anne Chiang;Welcome Bender;Mary Jane Shimell

  • The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1.

    Mary Jane Shimell;Edwin L. Ferguson;Steven R. Childs;Michael B. O'Connor;Michael B. O'Connor

  • Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster

    James T. Warren;Anna Petryk;Guillermo Marqués;Michael Jarcho

  • The Drosophila BMP Type II Receptor Wishful Thinking Regulates Neuromuscular Synapse Morphology and Function

    Guillermo Marqués;Hong Bao;Theodor E. Haerry;Mary Jane Shimell

  • The Insect Neuropeptide PTTH Activates Receptor Tyrosine Kinase Torso to Initiate Metamorphosis

    Kim F. Rewitz;Naoki Yamanaka;Lawrence I. Gilbert;Michael B. O’Connor

  • Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family

    Anthea Letsou;Kavita Arora;Jeffrey L Wrana;Karl Simin

  • Twisted gastrulation is a conserved extracellular BMP antagonist

    Jeffrey J. Ross;Osamu Shimmi;Peter Vilmos;Anna Petryk

  • Facilitated Transport of a Dpp/Scw Heterodimer by Sog/Tsg Leads to Robust Patterning of the Drosophila Blastoderm Embryo

    Osamu Shimmi;David M Umulis;Hans G Othmer;Michael B O'Connor

  • The Drosophila disembodied gene controls late embryonic morphogenesis and codes for a cytochrome P450 enzyme that regulates embryonic ecdysone levels.

    V.M. Chavez;G. Marques;J.P. Delbecque;K. Kobayashi

  • Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing.

    Michael B. O'Connor;David Umulis;Hans G. Othmer;Seth S. Blair

  • Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in Diptera.

    Hajime Ono;Kim F. Rewitz;Tetsuro Shinoda;Kyo Itoyama

  • Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis.

    James T. Warren;Anna Petryk;Guillermo Marqués;Jean Philippe Parvy

Frequent Co-Authors

Lawrence I. Gilbert
Lawrence I. Gilbert University of North Carolina at Chapel Hill
Welcome Bender
Welcome Bender Harvard University
Jeffrey A. Simon
Jeffrey A. Simon University of Minnesota
Joan Massagué
Joan Massagué Memorial Sloan Kettering Cancer Center
Hans G. Othmer
Hans G. Othmer University of Minnesota
Michael H. Malamy
Michael H. Malamy Tufts University
Jeffrey L. Wrana
Jeffrey L. Wrana Lunenfeld-Tanenbaum Research Institute
Tzumin Lee
Tzumin Lee University of Michigan–Ann Arbor
Liliana Attisano
Liliana Attisano University of Toronto
Thomas P. Neufeld
Thomas P. Neufeld University of Minnesota

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