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Molecular Biology

D-Index
65
Citations
13365
World Ranking
1681
National Ranking
849

Overview

Daniel S. Greenspan is affiliated with the University of Wisconsin-Madison in the United States. Their research spans various fields within medicine and biochemistry, genetics, and molecular biology, with particular focus on cellular and molecular neuroscience, neurology, cell biology, periodontics, and rheumatology.

The main research topics covered by Daniel S. Greenspan include:

  • Cellular Mechanics and Interactions
  • Axon Guidance and Neuronal Signaling
  • Neuroblastoma Research and Treatments
  • Oral Microbiology and Periodontitis Research
  • Bone and Dental Protein Studies
  • Periodontal Regeneration and Treatments
  • Transplantation: Methods and Outcomes

Their recent publications demonstrate a broad interest in molecular mechanisms underlying neurological function, dental health, and transplantation. Selected recent papers include:

  • Precise Spatiotemporal Control of Nodal Na+ Channel Clustering by Bone Morphogenetic Protein-1/Tolloid-like Proteinases, 2020, Neuron
  • Proteinase Bone Morphogenetic Protein 1, but Not Tolloid-like 1, Plays a Dominant Role in Maintaining Periodontal Homeostasis, 2020, Journal of Periodontology
  • Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation, 2020, Transplantation Direct
  • Ablation of Mitochondrial RCC1-L Induces Nigral Dopaminergic Neurodegeneration and Parkinsonian-like Motor Symptoms, 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • Author Correction: Proteolysis of the Low Density Lipoprotein Receptor by Bone Morphogenetic Protein-1 Regulates Cellular Cholesterol Uptake, 2020, Scientific Reports

The publication venues associated with Daniel S. Greenspan reflect interdisciplinary work across neuroscience, periodontology, transplantation, and molecular biology:

  • Neuron
  • Journal of Periodontology
  • Transplantation Direct
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports

Collaborators frequently working with Daniel S. Greenspan include Yael Eshed-Eisenbach, Jérôme Devaux, Anna Vainshtein, Ofra Golani, and Se-Jin Lee. These collaborations indicate a network spanning neuroscience, molecular biology, and medical research fields.

Best Publications

  • Bone Morphogenetic Protein-1: The Type I Procollagen C-Proteinase

    Efrat Kessler;Kazuhiko Takahara;Luba Biniaminov;Marina Brusel

  • Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases

    Neil M. Wolfman;Alexandra C. McPherron;William N. Pappano;Monique V. Davies

  • IL-17–dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants

    William J. Burlingham;Robert B. Love;Robert B. Love;Ewa Jankowska-Gan;Lynn D. Haynes

  • Mammalian BMP-1/Tolloid-Related Metalloproteinases, Including Novel Family Member Mammalian Tolloid-Like 2, Have Differential Enzymatic Activities and Distributions of Expression Relevant to Patterning and Skeletogenesis

    Ian C. Scott;Ira L. Blitz;William N. Pappano;Yasutada Imamura

  • BMP1 controls TGFβ1 activation via cleavage of latent TGFβ-binding protein

    Gaoxiang Ge;Daniel S. Greenspan

  • Multiple Bone Morphogenetic Protein 1-related Mammalian Metalloproteinases Process Pro-lysyl Oxidase at the Correct Physiological Site and Control Lysyl Oxidase Activation in Mouse Embryo Fibroblast Cultures

    Mehmet Ilhan Uzel;Ian C. Scott;Hermik Babakhanlou-Chase;Amitha H. Palamakumbura

  • The Bone Morphogenetic Protein 1/Tolloid-like Metalloproteinases

    Delana R. Hopkins;Sunduz Keles;Daniel S. Greenspan

  • A missense mutation in type VII collagen in two affected siblings with recessive dystrophic epidermolysis bullosa

    Angela M. Christiano;Daniel S. Greenspan;Guy G. Hoffman;Xin Zhang

  • Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues.

    K Takahara;G E Lyons;D S Greenspan

  • GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells.

    Gaoxiang Ge;Delana R. Hopkins;Wen-Bin Ho;Daniel S. Greenspan

  • Bone Morphogenetic Protein 1 Is an Extracellular Processing Enzyme of the Laminin 5 γ2 Chain

    Satoshi Amano;Ian C. Scott;Kazuhiko Takahara;Manuel Koch

  • Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction.

    Koichi S. Kobayashi;Min Luo;Yue Zhang;David C Wilkes

  • Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid

    Noboru Suzuki;Patricia A. Labosky;Yasuhide Furuta;Linda Hargett

  • ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation.

    Carine Le Goff;Fanny Morice-Picard;Nathalie Dagoneau;Lauren W Wang

  • Structural organization of the human type VII collagen gene (COL7A1), composed of more exons than any previously characterized gene

    Angela M. Christiano;Guy G. Hoffman;Linda C. Chung-Honet;Seungbok Lee

  • Attenuated BMP1 Function Compromises Osteogenesis, Leading to Bone Fragility in Humans and Zebrafish

    P.V. Asharani;Katharina Keupp;Oliver Semler;Wenshen Wang

  • Homologues of Twisted gastrulation are extracellular cofactors in antagonism of BMP signalling

    Ian C. Scott;Ira L. Blitz;William N. Pappano;Sarah A. Maas

  • Developmental roles of the BMP1/TLD metalloproteinases.

    Gaoxiang Ge;Daniel S. Greenspan

  • Bone Morphogenetic Protein-1 Processes Probiglycan

    Ian C. Scott;Yasutada Imamura;William N. Pappano;James M. Troedel

  • BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan.

    Eva M. Gonzalez;Charles C. Reed;Gregory Bix;Jian Fu

Frequent Co-Authors

Jouni Uitto
Jouni Uitto Thomas Jefferson University
Douglas R. Keene
Douglas R. Keene Shriners Hospitals for Children - Portland
William J. Burlingham
William J. Burlingham University of Wisconsin–Madison
Angela M. Christiano
Angela M. Christiano Columbia University
Thomas B. Shows
Thomas B. Shows Roswell Park Cancer Institute
David E. Birk
David E. Birk University of South Florida
M. Peter Marinkovich
M. Peter Marinkovich Stanford University
Jian Q. Feng
Jian Q. Feng Texas A&M University
Dario A. A. Vignali
Dario A. A. Vignali University of Pittsburgh
Jeffrey M. Davidson
Jeffrey M. Davidson Vanderbilt University

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