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Philip C. Trackman

Philip C. Trackman

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10528
World Ranking
13950
National Ranking
5893

Overview

Philip C. Trackman is affiliated with Boston University in the United States. Their research spans the fields of biochemistry, genetics, and molecular biology, with significant contributions also intersecting with medicine. Their work primarily engages with several subfields including molecular biology, genetics, pathology and forensic medicine, cell biology, and rheumatology.

The scope of their research topics covers areas such as microbial metabolism and enzyme function, connective tissue disorders research, alcohol consumption and health effects, aldose reductase and taurine, Wnt/β-catenin signaling in development and cancer, eosinophilic disorders and syndromes, and coagulation, bradykinin, polyphosphates, and angioedema.

Trackman has published multiple papers, several of which have appeared in the International Journal of Molecular Sciences. Notable recent papers include:

  • Functions and Mechanisms of Pro-Lysyl Oxidase Processing in Cancers and Eye Pathologies with a Focus on Diabetic Retinopathy (2022, International Journal of Molecular Sciences)
  • Multifunctional Lysyl Oxidases (2023, International Journal of Molecular Sciences)

Other papers related to broader collaborative efforts include:

  • β-Catenin mediates glucose-dependent insulinotropic polypeptide increases in lysyl oxidase expression in osteoblasts (2021, Bone Reports)
  • The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice (2023, International Journal of Molecular Sciences)
  • Deletion of mouse lysyl oxidase in megakaryocytes affects bone properties in a sex-dependent manner (2024, Blood)

Frequent co-authors in Trackman's research network include Yaser Peymanfar, Sayon Roy, Eileen J. Daley, Faranak Mahjour, and Neha Shrestha.

The primary publication venues for Trackman's work are:

  • International Journal of Molecular Sciences
  • Bone Reports
  • Blood

The breadth of Trackman's research contributions reflects a focus on enzyme functions related to lysyl oxidases and their roles in disease mechanisms, particularly in cancer, connective tissue abnormalities, and metabolic signaling pathways.

Best Publications

  • Properties and function of lysyl oxidase.

    Herbert M. Kagan;Philip C. Trackman

  • Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways.

    Mani Alikhani;Zoubin Alikhani;Coy Boyd;Christine M. MacLellan

  • Reaction of aortic lysyl oxidase with beta-aminopropionitrile.

    S S Tang;P C Trackman;H M Kagan

  • A role for advanced glycation end products in diminished bone healing in type 1 diabetes.

    Ronaldo B. Santana;Lei Xu;Hermik Babakhanlou Chase;Salomon Amar

  • A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samples.

    Amitha H. Palamakumbura;Philip C. Trackman

  • Multiple Bone Morphogenetic Protein 1-related Mammalian Metalloproteinases Process Pro-lysyl Oxidase at the Correct Physiological Site and Control Lysyl Oxidase Activation in Mouse Embryo Fibroblast Cultures

    Mehmet Ilhan Uzel;Ian C. Scott;Hermik Babakhanlou-Chase;Amitha H. Palamakumbura

  • Enhanced Chondrogenesis and Wnt Signaling in PTH‐Treated Fractures

    Sanjeev Kakar;Thomas A Einhorn;Siddharth Vora;Lincoln J Miara

  • Advanced Glycation End Products Enhance Expression of Pro-apoptotic Genes and Stimulate Fibroblast Apoptosis through Cytoplasmic and Mitochondrial Pathways

    Zoubin Alikhani;Mani Alikhani;Coy M. Boyd;Kiyoko Nagao

  • Post-translational glycosylation and proteolytic processing of a lysyl oxidase precursor.

    P.C. Trackman;D Bedell-Hogan;J Tang;H.M. Kagan

  • Diabetes-enhanced Inflammation and Apoptosis—Impact on Periodontal Pathology

    D.T. Graves;R. Liu;M. Alikhani;H. Al-Mashat

  • Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis

    M. Karima;A. Kantarci;T. Ohira;H. Hasturk

  • Connective tissue growth factor in drug-induced gingival overgrowth.

    M. Ilhan Uzel;Alpdogan Kantarci;Alpdogan Kantarci;Hsiang-Hsi Hong;Cem Uygur

  • Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor.

    Mani Alikhani;Christine M. MacLellan;Markos Raptis;Siddarth Vora

  • Cloning of rat aorta lysyl oxidase cDNA: complete codons and predicted amino acid sequence.

    Philip C. Trackman;Ann Marie Pratt;Andrzej Wolanski;Shiow Shih Tang

  • Regulation of lysyl oxidase, collagen, and connective tissue growth factor by TGF-beta1 and detection in human gingiva.

    H.-H. Hong;Mehmet Ilhan Uzel;Chunni Duan;M. C. Sheff

  • Oxidation, cross-linking, and insolubilization of recombinant tropoelastin by purified lysyl oxidase.

    D. Bedell-Hogan;P. Trackman;W. Abrams;J. Rosenbloom

  • Structural and catalytic properties of copper in lysyl oxidase

    S N Gacheru;P C Trackman;M A Shah;C Y O'Gara

  • Diverse Biological Functions of Extracellular Collagen Processing Enzymes

    Philip C. Trackman

  • Molecular and Clinical Aspects of Drug-induced Gingival Overgrowth

    P.C. Trackman;A. Kantarci

  • CCN2, CONNECTIVE TISSUE GROWTH FACTOR, STIMULATES COLLAGEN DEPOSITION BY GINGIVAL FIBROBLASTS VIA MODULE 3 AND α6- AND β1 INTEGRINS

    Edwin C.K. Heng;Yuanyi Huang;Samuel A. Black;Philip C. Trackman

Frequent Co-Authors

Gail E. Sonenshein
Gail E. Sonenshein Tufts University
Katya Ravid
Katya Ravid Boston University
Dana T. Graves
Dana T. Graves University of Pennsylvania
Louis C. Gerstenfeld
Louis C. Gerstenfeld Boston University
Hatice Hasturk
Hatice Hasturk Harvard University
Joseph E. Italiano
Joseph E. Italiano Boston Children's Hospital
Robert P. Mecham
Robert P. Mecham Washington University in St. Louis
Johannes A. Eble
Johannes A. Eble University of Münster
Matthew A. Nugent
Matthew A. Nugent University of Massachusetts Lowell
Andreas Peschel
Andreas Peschel University of Tübingen

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