World's Best Scientists 2026 revealed!
Louis C. Gerstenfeld

Louis C. Gerstenfeld

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
29501
World Ranking
2941
National Ranking
1505

Medicine

D-Index
86
Citations
29583
World Ranking
14048
National Ranking
7127

Overview

Louis C. Gerstenfeld is affiliated with Boston University in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans 37 publications in Medicine and 34 in Biochemistry, Genetics and Molecular Biology, reflecting a broad engagement with both clinical and molecular aspects of health sciences.

The subfields of study associated with Gerstenfeld's work include Molecular Biology, Genetics, Epidemiology, Rheumatology, and Surgery. This diverse range highlights a multidisciplinary approach, incorporating cellular and genetic mechanisms alongside clinical treatments and disease patterns.

Key topics addressed in their research focus on bone and musculoskeletal health. These include:

  • Bone fractures and treatments
  • Osteoarthritis treatment and mechanisms
  • Bone metabolism and diseases
  • Bone health and osteoporosis research
  • Genetic syndromes and imprinting
  • Inflammatory mediators and NSAID effects
  • Orthopaedic implants and arthroplasty

Gerstenfeld has published frequently in several scientific venues. The most common publication sources are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Methods in molecular biology
  • Journal of Cellular Physiology
  • Bone Reports
  • eLife

Some of their recent publications include:

  • "Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations" (2022, eLife)
  • "LOXL2 promotes aggrecan and gender-specific anabolic differences to TMJ cartilage" (2020, Scientific Reports)
  • "Epidemiology, Clinical Assessments, and Current Treatments of Nonunions" (2020, Current Osteoporosis Reports)
  • "Global transcriptomic analysis of a murine osteocytic cell line subjected to spaceflight" (2021, The FASEB Journal)
  • "Overview of Skeletal Repair (Fracture Healing and Its Assessment)" (2020, Methods in molecular biology)

Collaborations play a significant role in Gerstenfeld's research, with frequent co-authors including Elise F. Morgan, Beth Bragdon, Amira I. Hussein, Basel M. Al-Barghouthi, and Will Rosenow. These collaborations span multiple publications and contribute to the interdisciplinary character of their body of work.

Best Publications

  • Fracture healing: mechanisms and interventions

    Thomas A. Einhorn;Louis C. Gerstenfeld

  • Fracture healing as a post‐natal developmental process: Molecular, spatial, and temporal aspects of its regulation

    Louis C. Gerstenfeld;Dennis M. Cullinane;George L. Barnes;Dana T. Graves

  • BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing.

    Kunikazu Tsuji;Amitabha Bandyopadhyay;Brian D Harfe;Karen Cox

  • Differential Temporal Expression of Members of the Transforming Growth Factor β Superfamily During Murine Fracture Healing

    Tae-Joon Cho;Tae-Joon Cho;Louis C. Gerstenfeld;Thomas A. Einhorn

  • Molecular Mechanisms Controlling Bone Formation during Fracture Healing and Distraction Osteogenesis

    Z.S. AI-Aql;A.S. Alagl;D.T. Graves;L.C. Gerstenfeld

  • The hypoxia-inducible factor α pathway couples angiogenesis to osteogenesis during skeletal development

    Ying Wang;Chao Wan;Lianfu Deng;Ximeng Liu

  • Expression of Osteoprotegerin, Receptor Activator of NF-κB Ligand (Osteoprotegerin Ligand) and Related Proinflammatory Cytokines During Fracture Healing

    Tamiyo Kon;Tamiyo Kon;Tae Joon Cho;Tae Joon Cho;Toshimi Aizawa;Toshimi Aizawa;Masashi Yamazaki

  • Growth Factor Regulation of Fracture Repair

    George L. Barnes;Paul J. Kostenuik;Louis C. Gerstenfeld;Thomas A. Einhorn

  • Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells.

    Michael A. Aronow;Louis C. Gerstenfeld;Thomas A. Owen;Melissa S. Tassinari

  • Activation of the hypoxia-inducible factor-1α pathway accelerates bone regeneration

    Chao Wan;Shawn R. Gilbert;Ying Wang;Xuemei Cao

  • Impaired Fracture Healing in the Absence of TNF‐α Signaling: The Role of TNF‐α in Endochondral Cartilage Resorption

    Louis C. Gerstenfeld;T. J. Cho;T. Kon;T. Aizawa

  • Expression of differentiated function by mineralizing cultures of chicken osteoblasts.

    Louis C. Gerstenfeld;Louis C. Gerstenfeld;Stewart D. Chipman;Stewart D. Chipman;Julie Glowacki;Jane B. Lian

  • Diabetes Interferes with the Bone Formation by Affecting the Expression of Transcription Factors that Regulate Osteoblast Differentiation

    Huafei Lu;Douglas Kraut;Louis C. Gerstenfeld;Dana T. Graves

  • Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways.

    Mani Alikhani;Zoubin Alikhani;Coy Boyd;Christine M. MacLellan

  • Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs

    Louis C. Gerstenfeld;Mark Thiede;Karen Seibert;Cindy Mielke

  • Enhancement of Experimental Fracture-Healing by Systemic Administration of Recombinant Human Parathyroid Hormone (PTH 1-34)

    Yaser M. Alkhiary;Louis C. Gerstenfeld;Elizabeth Krall;Michael Westmore

  • Mechanism of action and morphologic changes in the alveolar bone in response to selective alveolar decortication–facilitated tooth movement

    S. Susan Baloul;Louis C. Gerstenfeld;Elise F. Morgan;Roberto S. Carvalho

  • Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity.

    Rayyan A Kayal;Dimitris Tsatsas;Megan A Bauer;Brian Allen

  • Micro-computed tomography assessment of fracture healing: Relationships among callus structure, composition, and mechanical function

    Elise F. Morgan;Zachary D. Mason;Karen B. Chien;Anthony J. Pfeiffer

  • Diabetes Causes Decreased Osteoclastogenesis, Reduced Bone Formation, and Enhanced Apoptosis of Osteoblastic Cells in Bacteria Stimulated Bone Loss

    Hongbing He;Rongkun Liu;Tesfahun Desta;Cataldo Leone

Frequent Co-Authors

Thomas A. Einhorn
Thomas A. Einhorn Boston University
Dana T. Graves
Dana T. Graves University of Pennsylvania
Jane B. Lian
Jane B. Lian University of Vermont
Gary S. Stein
Gary S. Stein University of Vermont
Marc D. McKee
Marc D. McKee McGill University
Melvin J. Glimcher
Melvin J. Glimcher Harvard University
Antonio Nanci
Antonio Nanci University of Montreal
Thomas L. Clemens
Thomas L. Clemens United States Department of Veterans Affairs
Mary L. Bouxsein
Mary L. Bouxsein Beth Israel Deaconess Medical Center
Mark W. Grinstaff
Mark W. Grinstaff Boston University

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