World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
21830
World Ranking
17396
National Ranking
191

Overview

Janine T. Erler is affiliated with the University of Copenhagen in Denmark. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, where they have contributed extensively to oncology, molecular biology, cell biology, surgery, and pulmonary and respiratory medicine.

Their scientific work focuses on a range of topics, highlighting:

  • Cancer Cells and Metastasis
  • Cellular Mechanics and Interactions
  • Cell Adhesion Molecules Research
  • Cancer, Hypoxia, and Metabolism
  • Tissue Engineering and Regenerative Medicine
  • Peptidase Inhibition and Analysis
  • Microbial Metabolism and Enzyme Function

Janine T. Erler has published in a variety of scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Nature Communications
  • Gastroenterology
  • Advanced Healthcare Materials

Frequent co-authors collaborating with Erler include:

  • Raphael Reuten
  • Chris D. Madsen
  • Alejandro E. Mayorca-Guiliani
  • Maria Rafaeva
  • Kamilla Westarp Zornhagen

Notable recent publications encompass a variety of studies related to cancer progression, cellular mechanics, and tumor microenvironments. These include:

  • Basement membrane stiffness determines metastases formation, 2021, published in Nature Materials
  • Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade, 2021, published in Nature Communications
  • Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer, 2021, published in Journal of Experimental & Clinical Cancer Research
  • Filopodia rotate and coil by actively generating twist in their actin shaft, 2022, published in Nature Communications
  • Framing cancer progression: influence of the organ- and tumour-specific matrisome, 2020, published in FEBS Journal

Best Publications

  • Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

    Kandice R. Levental;Hongmei Yu;Laura Kass;Johnathon N. Lakins

  • Retraction Note: Lysyl oxidase is essential for hypoxia-induced metastasis

    Janine T. Erler;Kevin L. Bennewith;Monica Nicolau;Nadja Dornhöfer

  • Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

    Thomas R. Cox;Janine T. Erler

  • Pre-metastatic niches: organ-specific homes for metastases

    Héctor Peinado;Haiying Zhang;Irina R. Matei;Bruno Costa-Silva

  • Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

    Janine T. Erler;Kevin L. Bennewith;Kevin L. Bennewith;Thomas R. Cox;Georgina Lang

  • The rationale for targeting the LOX family in cancer.

    Holly E. Barker;Thomas R. Cox;Thomas R. Cox;Janine T. Erler;Janine T. Erler

  • LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis

    Thomas R. Cox;Demelza Bird;Ann-Marie Baker;Holly E. Barker

  • The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

    Thomas R. Cox;Thomas R. Cox;Robin M. H. Rumney;Erwin M. Schoof;Lara Perryman

  • Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance.

    Janine T Erler;Christopher Cawthorne;Kaye J Williams;Marianne Koritzinsky

  • Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis.

    Laura Kass;Janine T. Erler;Micah Dembo;Valerie M. Weaver

  • Three-dimensional context regulation of metastasis

    Janine T. Erler;Valerie M. Weaver

  • Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.

    A. M Baker;D Bird;G Lang;T. R Cox;T. R Cox

  • LOXL2-Mediated Matrix Remodeling in Metastasis and Mammary Gland Involution

    Holly E. Barker;Joan Chang;Thomas R. Cox;Georgina Lang

  • Lysyl oxidase mediates hypoxic control of metastasis.

    Janine T. Erler;Amato J. Giaccia

  • Targeting ECM Disrupts Cancer Progression.

    Freja A. Venning;Lena Wullkopf;Janine T. Erler

  • Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.

    Bryan W Miller;Jennifer P Morton;Mark Pinese;Grazia Saturno

  • The Role of Lysyl Oxidase in SRC-Dependent Proliferation and Metastasis of Colorectal Cancer

    Ann-Marie Baker;Thomas R. Cox;Demelza Bird;Georgina Lang

  • Cancer cells' ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential.

    Lena Wullkopf;Ann Katrine V. West;Natascha Leijnse;Thomas R. Cox;Thomas R. Cox

  • STRIPAK components determine mode of cancer cell migration and metastasis

    Chris D Madsen;Steven Hooper;Melda Tozluoglu;Andreas Bruckbauer

  • Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

    Mauro Degli Esposti;Janine T. Erler;John A. Hickman;Caroline Dive

Frequent Co-Authors

Amato J. Giaccia
Amato J. Giaccia Stanford University
Quynh-Thu Le
Quynh-Thu Le Stanford University
Julia S. Johansen
Julia S. Johansen Copenhagen University Hospital
Morten A. Karsdal
Morten A. Karsdal University of Southern Denmark
Andreas Kjaer
Andreas Kjaer University of Copenhagen
Albert C. Koong
Albert C. Koong The University of Texas MD Anderson Cancer Center
Valerie M. Weaver
Valerie M. Weaver University of California, San Francisco
Manuel Koch
Manuel Koch University of Cologne
Jeffrey C. Bamber
Jeffrey C. Bamber Institute of Cancer Research

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