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Biology and Biochemistry

D-Index
58
Citations
52581
World Ranking
12863
National Ranking
264

Overview

Héctor Peinado is affiliated with the Spanish National Cancer Research Centre in Spain. Their research focuses primarily on areas within biochemistry, genetics, and molecular biology, with significant contributions also made in medicine.

The main subfields of their work include molecular biology, cancer research, immunology, oncology, and immunology and allergy. Their research topics concentrate on extracellular vesicles in disease, microRNA in disease regulation, RNA interference and gene delivery, cell adhesion molecules research, immunotherapy and immune responses, circular RNAs in diseases, and nanoplatforms for cancer theranostics.

Héctor Peinado has a number of recent publications, including:

  • "The power of imaging to understand extracellular vesicle biology in vivo" (2021, Nature Methods)
  • "Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism" (2021, Nature Cancer)
  • "ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells" (2020, Nature Communications)
  • "Melanoma-derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes" (2022, Journal of Extracellular Vesicles)
  • "In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells" (2020, Nature Communications)

Their frequent coauthors are:

  • Susana García-Silva
  • Marta Hergueta-Redondo
  • Sara Sánchez-Redondo
  • Pilar Ximénez-Embún
  • Alberto Hernández-Barranco

Héctor Peinado's research has been published extensively in several venues, with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Nature Communications
  • Frontiers in Cell and Developmental Biology
  • Journal of Extracellular Vesicles

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • Tumour exosome integrins determine organotropic metastasis

    Ayuko Hoshino;Bruno Costa-Silva;Tang-Long Shen;Goncalo Rodrigues

  • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

    Héctor Peinado;Maša Alečković;Simon Lavotshkin;Irina Matei

  • Snail, ZEB and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

    Héctor Peinado;David Olmeda;Amparo Cano

  • Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

    Bruno Costa-Silva;Nicole M. Aiello;Allyson J. Ocean;Swarnima Singh

  • Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

    Annette Becker;Basant Kumar Thakur;Joshua Mitchell Weiss;Han Sang Kim;Han Sang Kim

  • Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.

    Haiying Zhang;Daniela Freitas;Han Sang Kim;Han Sang Kim;Kristina Fabijanic

  • Pre-metastatic niches: organ-specific homes for metastases

    Héctor Peinado;Haiying Zhang;Irina R. Matei;Bruno Costa-Silva

  • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors.

    Victoria Bolós;Hector Peinado;Mirna A Pérez-Moreno;Mirna A Pérez-Moreno;Mario F Fraga

  • Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

    Ayuko Hoshino;Ayuko Hoshino;Han Sang Kim;Han Sang Kim;Linda Bojmar;Linda Bojmar;Linda Bojmar;Kofi Ennu Gyan

  • The perivascular niche regulates breast tumour dormancy

    Cyrus M. Ghajar;Héctor Peinado;Hidetoshi Mori;Irina R. Matei

  • Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex.

    Hector Peinado;Esteban Ballestar;Manel Esteller;Amparo Cano

  • Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.

    Hector Peinado;Miguel Quintanilla;Amparo Cano

  • Transcriptional regulation of cadherins during development and carcinogenesis

    Héctor Peinado;Francisco Portillo;Amparo Cano

  • The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts

    Héctor Peinado;Simon Lavotshkin;Simon Lavotshkin;David Lyden

  • Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.

    Ilaria Malanchi;Hector Peinado;Deepika Kassen;Thomas Hussenet

  • A molecular role for lysyl oxidase-like 2 enzyme in Snail regulation and tumor progression

    Héctor Peinado;Maria Del Carmen Iglesias-de la Cruz;David Olmeda;Katalin Csiszar

  • HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition.

    Sylvie Thuault;E-Jean Tan;Hector Peinado;Amparo Cano

  • Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition.

    Gema Moreno-Bueno;Eva Cubillo;David Sarrió;Héctor Peinado

  • The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells.

    Ofelia M. Martínez-Estrada;Albert Cullerés;Francesc X. Soriano;Hector Peinado

Frequent Co-Authors

Amparo Cano
Amparo Cano Spanish National Research Council
David Lyden
David Lyden Cornell University
Gema Moreno-Bueno
Gema Moreno-Bueno The University of Texas MD Anderson Cancer Center
Yibin Kang
Yibin Kang Princeton University
Hernando A. del Portillo
Hernando A. del Portillo University of Barcelona
Henrik Molina
Henrik Molina Rockefeller University
María Yáñez-Mó
María Yáñez-Mó Spanish National Research Council
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute
Mina J. Bissell
Mina J. Bissell Lawrence Berkeley National Laboratory

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