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Antonio García de Herreros

Antonio García de Herreros

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
24183
World Ranking
5843
National Ranking
87

Overview

Antonio García de Herreros is affiliated with Pompeu Fabra University in Spain and has a research focus primarily rooted in biochemistry, genetics, and molecular biology, with significant contributions to medicine. Their work spans several subfields including molecular biology, oncology, computational theory and mathematics, pharmacology, and cancer research.

The scientist's research covers a range of main topics such as:

  • Cancer Cells and Metastasis
  • Epigenetics and DNA Methylation
  • Computational Drug Discovery Methods
  • Metabolomics and Mass Spectrometry Studies
  • Microbial Natural Products and Biosynthesis
  • Cancer, Hypoxia, and Metabolism
  • Wnt/β-catenin signaling in development and cancer

Antonio García de Herreros has published recent papers including:

  • "Bioactivity descriptors for uncharacterized chemical compounds," 2021, Nature Communications
  • "Glutamine-Directed Migration of Cancer-Activated Fibroblasts Facilitates Epithelial Tumor Invasion," 2020, Cancer Research
  • "Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation," 2023, EMBO Reports
  • "Dual role of Snail1 as transcriptional repressor and activator," 2023, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • "Snail1 expression in endothelial cells controls growth, angiogenesis and differentiation of breast tumors," 2021, Theranostics

The venues where the scientist frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cancer Research
  • EMBO Reports
  • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Frequent co-authors collaborating with Antonio García de Herreros are:

  • Raúl Peña
  • Víctor M. Diaz
  • Beatriz del Valle-Pérez
  • Martino Bertoni
  • Miquel Duran-Frigola

The scientist's research addresses complex biological mechanisms, including signaling pathways relevant to cancer progression and resistance, transcriptional regulation, and tumor microenvironment dynamics. This body of work contributes to a multidisciplinary understanding spanning molecular biology and oncology.

Best Publications

  • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells.

    Eduard Batlle;Elena Sancho;Clara Francí;David Domínguez

  • Guidelines and definitions for research on epithelial–mesenchymal transition

    Jing Yang;Parker Antin;Geert Berx;Cédric Blanpain

  • Vitamin D3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling

    Héctor G. Pálmer;José Manuel González-Sancho;Jesús Espada;María T. Berciano

  • A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial–mesenchymal transition

    Manuel Beltran;Isabel Puig;Cristina Peña;José Miguel García

  • Regulation of E-cadherin/Catenin Association by Tyrosine Phosphorylation

    Santiago Roura;Susana Miravet;José Piedra;José Piedra;Antonio Garcı́a de Herreros

  • A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.

    Theresa Vincent;Theresa Vincent;Etienne P. A. Neve;Etienne P. A. Neve;Jill R. Johnson;Alexander Kukalev

  • Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression.

    Sandra Guaita;Isabel Puig;Clara Francı́;Marta Garrido

  • Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription implications for the epithelial–mesenchymal transition

    Robin E. Bachelder;Sang-Oh Yoon;Clara Franci;Antonio García de Herreros

  • Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor

    Nicolás Herranz;Diego Pasini;Víctor M Díaz;Clara Francí

  • Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells

    Toni Celià-Terrassa;Óscar Meca-Cortés;Francesca Mateo;Alexia Martínez de Paz

  • The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer

    José Manuel González-Sancho;Oscar Aguilera;José Miguel García;Natalia Pendás-Franco

  • p120 Catenin-associated Fer and Fyn tyrosine kinases regulate β-catenin Tyr-142 phosphorylation and β-catenin-α-catenin interaction

    Jose Piedra;Jose Piedra;Susana Miravet;Julio Castaño;Héctor G. Pálmer

  • Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells.

    Maria José Barberà;Maria José Barberà;Isabel Puig;David Domínguez;Sylvia Julien-Grille

  • Transcriptional crosstalk between TGF-β and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes.

    Jonas Fuxe;Theresa Vincent;Antonio Garcia de Herreros

  • Loss of E-cadherin Expression in Melanoma Cells Involves Up-regulation of the Transcriptional Repressor Snail

    Ina Poser;David Domı́nguez;Antonio Garcia de Herreros;Alinda Varnai

  • The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer.

    Héctor G Pálmer;María Jesús Larriba;José Miguel García;Paloma Ordóñez-Morán

  • Functional cooperation between Snail1 and twist in the regulation of ZEB1 expression during epithelial to mesenchymal transition.

    Natàlia Dave;Sandra Guaita-Esteruelas;Susana Gutarra;Àlex Frias

  • Regulation of β-catenin structure and activity by tyrosine phosphorylation.

    José Piedra;Daniel Martínez;Julio Castaño;Susana Miravet

  • Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients

    Mercedes A. Herrera;Alberto F. Herrera;Gemma Domínguez;Javier M. Silva

  • Phosphorylation Regulates the Subcellular Location and Activity of the Snail Transcriptional Repressor

    David Domínguez;Bàrbara Montserrat-Sentís;Ariadna Virgós-Soler;Sandra Guaita

Frequent Co-Authors

Alberto Muñoz
Alberto Muñoz Spanish National Research Council
J. Ignacio Casal
J. Ignacio Casal Spanish National Research Council
Ismo Virtanen
Ismo Virtanen University of Helsinki
Eduard Batlle
Eduard Batlle Institució Catalana de Recerca i Estudis Avançats
Shoukat Dedhar
Shoukat Dedhar University of British Columbia
Joaquín Arribas
Joaquín Arribas Institució Catalana de Recerca i Estudis Avançats
Amparo Cano
Amparo Cano Spanish National Research Council
Aristidis Moustakas
Aristidis Moustakas Uppsala University
Alain Puisieux
Alain Puisieux Claude Bernard University Lyon 1
Luciano Di Croce
Luciano Di Croce Centre for Genomic Regulation

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