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Biology and Biochemistry

D-Index
71
Citations
15421
World Ranking
6759
National Ranking
206

Overview

Catherine Tomasetto is affiliated with the Institute of Genetics and Molecular and Cellular Biology in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions also in Medicine. Within these broad areas, Tomasetto has focused extensively on Molecular Biology, Oncology, Cell Biology, Cancer Research, and Biochemistry.

Their work covers a range of topics related to cellular mechanisms and disease processes. Key topics include:

  • Cancer Cells and Metastasis
  • Lipid metabolism and biosynthesis
  • Endoplasmic Reticulum Stress and Disease
  • Cellular transport and secretion
  • Breast Cancer Treatment Studies
  • Cancer Risks and Factors
  • Heat shock proteins research

Several recent papers illustrate their active research role, including:

  • FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts (2020, The EMBO Journal)
  • Roles of Matrix Metalloproteinases and Their Natural Inhibitors in Metabolism: Insights into Health and Disease (2023, International Journal of Molecular Sciences)
  • Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR (2020, Cancers)
  • MOSPD2 is an endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis (2022, The Journal of Cell Biology)
  • Wnt5a Promotes Lysosomal Cholesterol Egress and Protects Against Atherosclerosis (2021, Circulation Research)

Their work has been published in several scientific journals, notably including:

  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Journal of Biological Chemistry
  • Atherosclerosis

Tomasetto collaborates frequently with other researchers, among them are Fabien Alpy, Corinne Wendling, Carole Mathelin, Guillaume Drin, and Massimo Lodi, reflecting active participation in collaborative research efforts.

Best Publications

  • Ultradian Rhythmicity of Ghrelin Secretion in Relation with GH, Feeding Behavior, and Sleep-Wake Patterns in Rats

    Virginie Tolle;Marie-Helene Bassant;Philippe Zizzari;Frederique Poindessous-Jazat

  • Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein.

    Olivier Lefebvre;Marie-Pierre Chenard;Régis Masson;José Linares

  • Positive selection of candidate tumor-suppressor genes by subtractive hybridization.

    Sam W. Lee;Catherine Tomasetto;Ruth Sager

  • Give lipids a START: the StAR-related lipid transfer (START) domain in mammals.

    Fabien Alpy;Catherine Tomasetto

  • Breast cancer-Associated pS2 protein: Synthesis and secretion by normal stomach mucosa

    M. C. Rio;J. P. Bellocq;J. Y. Daniel;C. Tomasetto

  • Ghrelin/motilin-related peptide is a potent prokinetic to reverse gastric postoperative ileus in rat.

    L. Trudel;C. Tomasetto;M. C. Rio;M. Bouin

  • The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity.

    Lionel Ballut;Brice Marchadier;Aurélie Baguet;Catherine Tomasetto

  • Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines.

    S. W. Lee;C. Tomasetto;D. Paul;Khandan Keyomarsi

  • Identification of Four Novel Human Genes Amplified and Overexpressed in Breast Carcinoma and Localized to the q11-q21.3 Region of Chromosome 17

    C. Tomasetto;C. Régnier;C. Moog-Lutz;M.G. Mattei

  • MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steroidogenesis

    Hidemichi Watari;Futoshi Arakane;Christel Moog-Lutz;Caleb B. Kallen

  • Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide.

    Catherine Tomasetto;Sherif M. Karam;Stephane Ribieras;Régis Masson

  • STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sites.

    Léa P Wilhelm;Corinne Wendling;Benoît Védie;Toshihide Kobayashi;Toshihide Kobayashi

  • EXPRESSION OF MATRIX METALLOPROTEINASES DURING RAT SKIN WOUND HEALING : EVIDENCE THAT MEMBRANE TYPE-1 MATRIX METALLOPROTEINASE IS A STROMAL ACTIVATOR OF PRO-GELATINASE A

    Akiko Okada;Catherine Tomasetto;Yves Lutz;Jean-Pierre Bellocq

  • Niemann-Pick C1 Disease: Correlations between NPC1 Mutations, Levels of NPC1 Protein, and Phenotypes Emphasize the Functional Significance of the Putative Sterol-Sensing Domain and of the Cysteine-Rich Luminal Loop

    Gilles Millat;Christophe Marçais;Catherine Tomasetto;Karim Chikh

  • Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma.

    Catherine H. Régnier;Catherine Tomasetto;Christel Moog-Lutz;Marie-Pierre Chenard

  • Epidermal growth factor (EGF/URO) induces expression of regulatory peptides in damaged human gastrointestinal tissues.

    Nicholas A. Wright;Richard Poulsom;Gordon W. H. Stamp;Peter A. Hall

  • hSP, the domain-duplicated homolog of pS2 protein, is co-expressed with pS2 in stomach but not in breast carcinoma.

    C. Tomasetto;M.C. Rio;C. Gautier;C. Wolf

  • Genetic determinants of pancreatic epsilon-cell development.

    R. S. Heller;M. Jenny;P. Collombat;A. Mansouri

  • STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER.

    Fabien Alpy;Adrien Rousseau;Yannick Schwab;Yannick Schwab;François Legueux

  • The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein.

    Fabien Alpy;Marie-Elisabeth Stoeckel;Andrée Dierich;Jean-Michel Escola

Frequent Co-Authors

Marie-Christine Rio
Marie-Christine Rio Grenoble Alpes University
Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Richard Lathe
Richard Lathe University of Edinburgh
Ruth Sager
Ruth Sager Harvard University
Sam W. Lee
Sam W. Lee Broad Institute
Olivier Lefebvre
Olivier Lefebvre University of Strasbourg
Jean-Luc Daval
Jean-Luc Daval University of Lorraine
Marie Paule Kieny
Marie Paule Kieny Drugs for Neglected Diseases Initiative

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