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Biology and Biochemistry

D-Index
76
Citations
19797
World Ranking
5071
National Ranking
98

Overview

Beat W. Schäfer is affiliated with the University of Zurich in Switzerland. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant publication record in subfields such as Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Cancer Research, and Hematology.

Their main topics of study include:

  • Sarcoma Diagnosis and Treatment
  • Protein Degradation and Inhibitors
  • CAR-T cell therapy research
  • RNA modifications and cancer
  • Chromatin Remodeling and Cancer
  • Acute Lymphoblastic Leukemia research
  • Cancer Genomics and Diagnostics

Beat W. Schäfer has contributed to a number of frequent publication venues, including:

  • Cancer Research
  • Nature Communications
  • Neoplasia
  • Leukemia
  • Cancers

Notable recent papers authored under their name include:

  • The KMT2A recombinome of acute leukemias in 2023, Leukemia
  • Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue sarcoma Study Group, Children's Oncology Group and Cooperative Weichteilsarkom-Studiengruppe, 2022, European Journal of Cancer
  • YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells, 2021, Oncogenesis
  • Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance, 2023, Science Advances
  • NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency, 2020, eLife

Frequent co-authors collaborating with Beat W. Schäfer include:

  • Marco Wachtel
  • Joana G. Marques
  • Quy A. Ngo
  • Javed Khan
  • Gloria Pedot

Best Publications

  • The S100 family of EF-hand calcium-binding proteins: functions and pathology.

    Beat W. Schäfer;Claus W. Heizmann

  • S100 proteins: structure, functions and pathology.

    Claus W Heizmann;Günter Fritz;Beat W Schäfer

  • The MLL recombinome of acute leukemias in 2013

    C. Meyer;J. Hofmann;T. Burmeister;D. Gröger

  • Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study

    Martin Schrappe;Maria Grazia Valsecchi;Claus R. Bartram;André Schrauder

  • Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia.

    T Flohr;T Flohr;A Schrauder;G Cazzaniga;R Panzer-Grümayer

  • New insights to the MLL recombinome of acute leukemias

    C. Meyer;E. Kowarz;J. Hofmann;A. Renneville

  • Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family

    Beat W. Schäfer;Roland Wicki;Dieter Engelkamp;Marie-geneviève Mattei

  • Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

    Laura Bonapace;Beat C. Bornhauser;Maike Schmitz;Gunnar Cario

  • Expression pattern of S100 calcium‐binding proteins in human tumors

    Evelyn C. Ilg;Beat W. Schäfer;Claus W. Heizmann

  • Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2.

    Stephan Lange;Daniel Auerbach;Patricia McLoughlin;Evelyne Perriard

  • Gene Expression Signatures Identify Rhabdomyosarcoma Subtypes and Detect a Novel t(2;2)(q35;p23) Translocation Fusing PAX3 to NCOA1

    Marco Wachtel;Marcel Dettling;Eva Koscielniak;Sabine Stegmaier

  • Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer.

    Yutaka Yonemura;Yoshio Endou;Keiichi Kimura;Sachio Fushida

  • Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins

    Michele Bernasconi;Andrew Remppis;William J. Fredericks;Frank J. Rauscher

  • Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E.

    D Engelkamp;B W Schäfer;M G Mattei;P Erne

  • Altered expression of the Ca2+-binding protein S100A1 in human cardiomyopathy

    Andrew Remppis;Andrew Remppis;Tobias Greten;Beat W. Schäfer;Peter Hunziker

  • Distinct subcellular localization of calcium binding S100 proteins in human smooth muscle cells and their relocation in response to rises in intracellular calcium.

    A. Mandinova;D. Atar;B.W. Schafer;M. Spiess

  • Calcium regulation of Ndr protein kinase mediated by S100 calcium‐binding proteins

    Thomas A. Millward;Claus W. Heizmann;Beat W. Schäfer;Brian A. Hemmings

  • Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia

    Gunnar Cario;Martin Stanulla;Bernard M. Fine;Oliver Teuffel

  • Expression analysis of S100 proteins and RAGE in human tumors using tissue microarrays

    Hsiao-Ling Hsieh;Beat W. Schäfer;Nobuyuki Sasaki;Claus W. Heizmann

  • Clinical significance of S100A4 and E-cadherin-related adhesion molecules in non-small cell lung cancer.

    K Kimura;Y Endo;Y Yonemura;C W Heizmann

Frequent Co-Authors

Claus W. Heizmann
Claus W. Heizmann University of Zurich
Martin Schrappe
Martin Schrappe Kiel University
Martin Stanulla
Martin Stanulla Hannover Medical School
Hélène Cavé
Hélène Cavé Université Paris Cité
Robert Kiss
Robert Kiss Université Libre de Bruxelles
Jos A. Cox
Jos A. Cox University of Geneva
Isabelle Salmon
Isabelle Salmon Université Libre de Bruxelles
Giovanni Cazzaniga
Giovanni Cazzaniga University of Milano-Bicocca
Rolf Marschalek
Rolf Marschalek Goethe University Frankfurt

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