D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 74 Citations 18,483 308 World Ranking 15221 National Ranking 465

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cancer
  • Internal medicine

Hélène Cavé mostly deals with Internal medicine, Minimal residual disease, Genetics, Leukemia and Acute lymphocytic leukemia. Her work carried out in the field of Internal medicine brings together such families of science as Gastroenterology, Endocrinology and Oncology. The study incorporates disciplines such as Gene rearrangement, Clinical trial and Prospective cohort study in addition to Minimal residual disease.

Her work on Genetics is being expanded to include thematically relevant topics such as Cancer research. Her research in Leukemia intersects with topics in Myeloid leukemia and BCL11B. Her Acute lymphocytic leukemia research integrates issues from Molecular biology, Childhood Acute Lymphoblastic Leukemia, Fusion gene and Cumulative incidence.

Her most cited work include:

  • Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – A Europe Against Cancer Program (1267 citations)
  • Clinical Significance of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia (699 citations)
  • Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data. (501 citations)

What are the main themes of her work throughout her whole career to date?

Hélène Cavé mainly investigates Internal medicine, Cancer research, Genetics, Noonan syndrome and Leukemia. She does research in Internal medicine, focusing on Minimal residual disease specifically. Hélène Cavé interconnects Clinical trial, B cell, Childhood Acute Lymphoblastic Leukemia, Immunophenotyping and Acute lymphocytic leukemia in the investigation of issues within Minimal residual disease.

The concepts of her Cancer research study are interwoven with issues in Mutation, Frameshift mutation, Neuroblastoma RAS viral oncogene homolog, Tumor suppressor gene and Juvenile myelomonocytic leukemia. Her Noonan syndrome study also includes fields such as

  • PTPN11 and related Dermatology,
  • Costello syndrome that intertwine with fields like HRAS and Cardiofaciocutaneous syndrome. Her Leukemia research incorporates elements of Haematopoiesis and Myeloid leukemia.

She most often published in these fields:

  • Internal medicine (43.73%)
  • Cancer research (20.34%)
  • Genetics (20.00%)

What were the highlights of her more recent work (between 2015-2021)?

  • Internal medicine (43.73%)
  • Noonan syndrome (17.29%)
  • Leukemia (17.29%)

In recent papers she was focusing on the following fields of study:

Hélène Cavé spends much of her time researching Internal medicine, Noonan syndrome, Leukemia, Pediatrics and Cancer research. Hélène Cavé combines subjects such as Gastroenterology, Endocrinology and Oncology with her study of Internal medicine. Her work deals with themes such as Phenotype, Costello syndrome, MAPK/ERK pathway and PTPN11, which intersect with Noonan syndrome.

She is interested in Minimal residual disease, which is a field of Leukemia. Her Pediatrics study also includes

  • Diabetes mellitus that intertwine with fields like Neonatal diabetes mellitus and Transient neonatal diabetes mellitus,
  • Cancer that connect with fields like Randomized controlled trial, Asparaginase, Retrospective cohort study and Survival rate. Her studies in Cancer research integrate themes in fields like B cell and Lymphoblastic Leukemia.

Between 2015 and 2021, her most popular works were:

  • The MLL recombinome of acute leukemias in 2017 (231 citations)
  • IKZF1plus Defines a New Minimal Residual Disease–Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia (78 citations)
  • ClinGen's RASopathy Expert Panel consensus methods for variant interpretation. (74 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

Her primary areas of study are Internal medicine, Leukemia, Noonan syndrome, Genetics and Minimal residual disease. Her Internal medicine study integrates concerns from other disciplines, such as Gastroenterology and Oncology. Her Leukemia study deals with the bigger picture of Immunology.

Her study focuses on the intersection of Immunology and fields such as Stem cell with connections in the field of Cancer research and RNA-binding protein. Her Noonan syndrome research includes elements of Endocrinology, Sudden death, KRAS, PTPN11 and MAPK/ERK pathway. Her research integrates issues of Clinical trial, Survival rate, Imatinib, Survival analysis and Transplantation in her study of Minimal residual disease.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – A Europe Against Cancer Program

J Gabert;E Beillard;V H J van der Velden;W Bi.
Leukemia (2003)

2070 Citations

Clinical Significance of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia

Cavé H;van der Werff ten Bosch J;Suciu S;Guidal C.
The New England Journal of Medicine (1998)

948 Citations

Activating Mutations in the ABCC8 Gene in Neonatal Diabetes Mellitus

Andrey P. Babenko;Michel Polak;Hélène Cavé;Kanetee Busiah.
The New England Journal of Medicine (2006)

748 Citations

Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data.

V H J van der Velden;G Cazzaniga;A Schrauder;J Hancock.
Leukemia (2007)

743 Citations

Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome

Tetsuya Niihori;Yoko Aoki;Yoko Narumi;Giovanni Neri.
Nature Genetics (2006)

615 Citations

The MLL recombinome of acute leukemias in 2013

C. Meyer;J. Hofmann;T. Burmeister;D. Gröger.
Leukemia (2013)

498 Citations

New insights to the MLL recombinome of acute leukemias

C. Meyer;E. Kowarz;J. Hofmann;A. Renneville.
Leukemia (2009)

467 Citations

The MLL recombinome of acute leukemias in 2017

C Meyer;T Burmeister;D Gröger;G Tsaur.
Leukemia (2018)

460 Citations

Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia

Elisabetta Flex;Valentina Petrangeli;Lorenzo Stella;Sabina Chiaretti.
Journal of Experimental Medicine (2008)

424 Citations

Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18–20 September 2008

M. Bruggemann;A. Schrauder;T. Raff;H. Pfeifer.
Leukemia (2010)

423 Citations

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