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Genetics

D-Index
57
Citations
11501
World Ranking
3418
National Ranking
233

Overview

Rolf Marschalek is affiliated with Goethe University Frankfurt in Germany. Their research focuses primarily on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant emphasis on Molecular Biology, Hematology, Public Health, Environmental and Occupational Health, Immunology, and Infectious Diseases.

The core topics of Marschalek's work encompass Acute Myeloid Leukemia Research, Acute Lymphoblastic Leukemia research, Protein Degradation and Inhibitors, CRISPR and Genetic Engineering, Advanced biosensing and bioanalysis techniques, Chronic Myeloid Leukemia Treatments, and Epigenetics and DNA Methylation.

Among the recent papers associated with their work are:

  • The KMT2A recombinome of acute leukemias in 2023, published in Leukemia
  • Limited neutralisation of the SARS-CoV-2 Omicron subvariants BA.1 and BA.2 by convalescent and vaccine serum and monoclonal antibodies, 2022, EBioMedicine
  • Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein, 2021, Blood
  • Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia, 2022, Blood
  • Clinical Implications of Minimal Residual Disease Detection in Infants With KMT2A-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol, 2021, Journal of Clinical Oncology

Frequent co-authors in Marschalek's collaborations include Claus Meyer, Patrizia Larghero, Giovanni Cazzaniga, Eric Kowarz, and Marius Külp.

The most common publication venues for Marschalek's work are:

  • Klinische Pädiatrie
  • Blood
  • Leukemia
  • SSRN Electronic Journal
  • Research Square (Research Square)

Best Publications

  • The MLL recombinome of acute leukemias in 2017

    C Meyer;T Burmeister;D Gröger;G Tsaur

  • The MLL recombinome of acute leukemias in 2013

    C. Meyer;J. Hofmann;T. Burmeister;D. Gröger

  • New insights to the MLL recombinome of acute leukemias

    C. Meyer;E. Kowarz;J. Hofmann;A. Renneville

  • Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines.

    Eric Kowarz;Denise Löscher;Rolf Marschalek

  • The MLL recombinome of acute leukemias.

    C. Meyer;B. Schneider;S. Jakob;S. Strehl

  • Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

    Huriye Cin;Claus Meyer;Ricarda Herr;Wibke G. Janzarik

  • Hydroxyurea for Treatment of Unresectable and Recurrent Meningiomas. II. Decrease in the Size of Meningiomas in Patients Treated with Hydroxyurea

    U M Schrell;M G Rittig;M Anders;U H Koch

  • Mechanisms of leukemogenesis by MLL fusion proteins.

    Rolf Marschalek

  • Diagnostic tool for the identification of MLL rearrangements including unknown partner genes

    Claus Meyer;Bjoern Schneider;Martin Reichel;Sieglinde Angermueller

  • Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth.

    Daniela Hartmann;Jessica Lucks;Sina Fuchs;Susanne Schiffmann

  • Prognostic significance of minimal residual disease in infants with acute lymphoblastic leukemia treated within the Interfant-99 protocol

    V H J Van der Velden;L Corral;M G Valsecchi;M W J C Jansen

  • Exon/intron structure of the human ALL‐1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias

    I. Nilson;K. LöCHNER;G. Siegler;J. Greil

  • The AF4·MLL fusion protein is capable of inducing ALL in mice without requirement of MLL·AF4

    Adelheid Bursen;Karen Schwabe;Brigitte Rüster;Reinhard Henschler

  • Hydroxyurea for treatment of unresectable and recurrent meningiomas. I. Inhibition of primary human meningioma cells in culture and in meningioma transplants by induction of the apoptotic pathway

    Uwe M. H. Schrell;Michael G. Rittig;Marc Anders;Franklin Kiesewetter

  • Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia.

    Brian V. Balgobind;Marry M. Van den Heuvel-Eibrink;Renee X. De Menezes;Dirk Reinhardt

  • Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement.

    M W J C Jansen;L Corral;V H J van der Velden;R Panzer-Grümayer

  • The acute lymphoblastic leukaemia cell line SEM with t(4;11) chromosomal rearrangement is biphenotypic and responsive to interleukin-7.

    Johann Greil;Martin Gramatzki;Renate Burger;Rolf Marschalek

  • Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia

    Alejandra Sanjuan-Pla;Clara Bueno;Cristina Prieto;Pamela Acha

  • Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation t(4;11): the DNA damage-repair model of translocation

    Martin Reichel;Esther Gillert;Iris Nilson;Gabi Siegler

  • Exon/intron structure of the human AF‐4 gene, a member of the AF‐4/LAF‐4/FMR‐2 gene family coding for a nuclear protein with structural alterations in acute leukaemia

    I Nilson;M Reichel;M G Ennas;R Greim

Frequent Co-Authors

Oskar A. Haas
Oskar A. Haas Medical University of Vienna
Christian Meyer
Christian Meyer Greifswald University Hospital
Jan Trka
Jan Trka Charles University
Rob Pieters
Rob Pieters Princess Máxima Center
Pablo Menendez
Pablo Menendez University of Barcelona
Thomas Klingebiel
Thomas Klingebiel Goethe University Frankfurt
Georg H. Fey
Georg H. Fey University of Erlangen-Nuremberg
Marry M. van den Heuvel-Eibrink
Marry M. van den Heuvel-Eibrink University Medical Center Utrecht
Eric Delabesse
Eric Delabesse Cancer Research Center of Toulouse
Rudolf Fahlbusch
Rudolf Fahlbusch University of Erlangen-Nuremberg

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