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Medicine

D-Index
106
Citations
70499
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6364
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618

Research.com Recognitions

  • 2003 - Fellow of the Royal Society, United Kingdom

Overview

Mel Greaves is a researcher affiliated with the Institute of Cancer Research in the United Kingdom. Their work spans multiple domains within medicine, biochemistry, genetics, and molecular biology, with particular focus on pediatrics, cancer research, and public health aspects related to childhood diseases.

The scientist's research primarily centers on topics such as childhood cancer survivors' quality of life and acute lymphoblastic leukemia (ALL) research. Additional subjects include cancer genomics and diagnostics, acute myeloid leukemia research, cancer, hypoxia, and metabolism, gut microbiota and health, as well as epigenetics and DNA methylation.

Among Mel Greaves's recent publications are:

  • Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia, 2021, Nature Cancer
  • Can we prevent childhood Leukaemia?, 2021, Leukemia
  • Gut microbiome immaturity and childhood acute lymphoblastic leukaemia, 2023, Nature Reviews. Cancer
  • Covert pre-leukaemic clones in healthy co-twins of patients with childhood acute lymphoblastic leukaemia, 2022, Leukemia
  • Association of Combined Focal 22q11.22 Deletion and IKZF1 Alterations With Outcomes in Childhood Acute Lymphoblastic Leukemia, 2021, JAMA Oncology

Frequent coauthors collaborating with Greaves include:

  • Anthony M. Ford
  • Marcela Braga Mansur
  • Caroline L. Furness
  • Joshua D. Schiffman
  • Nandita M. deSouza

Their scholarly contributions often appear in the following publication venues:

  • Leukemia
  • UNC Libraries
  • Nature Reviews. Cancer
  • Nature Cancer
  • BMC Ecology and Evolution

The scientist's work covers specific subfields such as pediatrics, perinatology and child health, public health, environmental and occupational health, molecular biology, cancer research, and hematology. This multidisciplinary scope reflects the interconnected nature of their research areas.

Mel Greaves was awarded the title Fellow of the Royal Society, United Kingdom, in 2003, recognizing contributions to their field.

Best Publications

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

    Angus G. Dalgleish;Peter C. L. Beverley;Paul R. Clapham;Dorothy H. Crawford

  • Genomic Classification and Prognosis in Acute Myeloid Leukemia

    Elli Papaemmanuil;Moritz Gerstung;Lars Bullinger;Verena I Gaidzik

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Clonal evolution in cancer

    Mel Greaves;Carlo C. Maley

  • Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

    J. Nangalia;C.E. Massie;E.J. Baxter;F.L. Nice

  • Acute lymphoblastic leukaemia.

    Hiroto Inaba;Mel Greaves;Charles G Mullighan

  • Expression of the CD34 gene in vascular endothelial cells.

    L Fina;H V Molgaard;D Robertson;N J Bradley

  • Genetic variegation of clonal architecture and propagating cells in leukaemia

    Kristina Anderson;Christoph Lutz;Frederik W. van Delft;Caroline M. Bateman

  • Origins of chromosome translocations in childhood leukaemia

    Mel F. Greaves;Joe Wiemels

  • Multilineage gene expression precedes commitment in the hemopoietic system

    Ming Hu;Diane Krause;Mel Greaves;Saul Sharkis

  • Infection, immune responses and the aetiology of childhood leukaemia

    Mel Greaves

  • Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment

    Myrtle Y. Gordon;Graham P. Riley;Suzanne M. Watt;Melvyn F. Greaves

  • Prenatal origin of acute lymphoblastic leukaemia in children

    JL Wiemels;G Cazzaniga;M Daniotti;OB Eden

  • Chromosome translocations and covert leukemic clones are generated during normal fetal development

    Hiroshi Mori;Susan M. Colman;Zhijian Xiao;Anthony M. Ford

  • Lineage promiscuity in hemopoietic differentiation and leukemia.

    M.F. Greaves;L.C. Chan;A.J.W. Furley;S.M. Watt

  • Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots

    Karin B. Gale;Anthony M. Ford;Reinald Repp;Arndt Borkhardt

  • Leukemia in twins: lessons in natural history.

    Mel F. Greaves;Ana Teresa Maia;Joseph L. Wiemels;Anthony M. Ford

  • Aetiology of acute leukaemia

    MF Greaves

  • Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia.

    M Y Gordon;C R Dowding;G P Riley;J M Goldman

Frequent Co-Authors

Lyndal Kearney
Lyndal Kearney Institute of Cancer Research
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Giovanni Cazzaniga
Giovanni Cazzaniga University of Milano-Bicocca
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Christine J. Harrison
Christine J. Harrison Newcastle University
Eve Roman
Eve Roman University of York
Richard S. Houlston
Richard S. Houlston Institute of Cancer Research
Andrea Biondi
Andrea Biondi University of Milano-Bicocca
Joseph L. Wiemels
Joseph L. Wiemels University of Southern California
Tariq Enver
Tariq Enver University College London

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