World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
47
Citations
8389
World Ranking
4124
National Ranking
466

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Mutation

His scientific interests lie mostly in Genetics, Gene, Molecular biology, Chromosomal translocation and Candidate gene. As part of his studies on Genetics, he often connects relevant areas like Young adult. His Molecular biology research incorporates themes from Complementary DNA, NUP98 Gene and Fusion transcript.

His Chromosomal translocation research integrates issues from Immunology, Cytokine Receptor Gene, Cytokine, Cytokine receptor and B cell. His work investigates the relationship between Candidate gene and topics such as Cytogenetics that intersect with problems in Chromosome Arm, DNA, Tandem repeat, Subtelomere and Telomere. In his research, Fluorescence in situ hybridization is intimately related to Genetic architecture, which falls under the overarching field of Genomics.

His most cited work include:

  • Genetic variegation of clonal architecture and propagating cells in leukaemia (644 citations)
  • Subtle chromosomal rearrangements in children with unexplained mental retardation. (426 citations)
  • Deregulated expression of cytokine receptor gene, CRLF2 , is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia (364 citations)

What are the main themes of his work throughout his whole career to date?

Lyndal Kearney focuses on Genetics, Molecular biology, Chromosomal translocation, Gene and Fluorescence in situ hybridization. His Molecular biology research includes elements of Cosmid, Chromosome 21, Tyrosine kinase, Gene mapping and Chromosome 7. His Chromosomal translocation study combines topics in areas such as Cancer research, Aneuploidy, Monosomy, Karyotype and Cytogenetics.

The Cytogenetics study combines topics in areas such as Pathology, DNA and Candidate gene. His research in Gene tackles topics such as Leukemia which are related to areas like T-cell receptor. His study in Fluorescence in situ hybridization is interdisciplinary in nature, drawing from both In situ hybridization, Complex Karyotype, Myeloid leukemia, Childhood Acute Myeloid Leukemia and Genetic heterogeneity.

He most often published in these fields:

  • Genetics (59.83%)
  • Molecular biology (35.90%)
  • Chromosomal translocation (34.19%)

What were the highlights of his more recent work (between 2010-2019)?

  • Genetics (59.83%)
  • Leukemia (12.82%)
  • Fusion gene (10.26%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Genetics, Leukemia, Fusion gene, Cancer stem cell and SNP array. His work in Exome sequencing, Phenotype, Single-cell analysis, Gene and Somatic evolution in cancer are all subfields of Genetics research. His work deals with themes such as CD135, Cytokine Receptor Gene and B cell, which intersect with Leukemia.

His biological study spans a wide range of topics, including Breakpoint, Clone, CDKN2A, breakpoint cluster region and Single-nucleotide polymorphism. His Cancer stem cell research incorporates elements of Genetic analysis, Genetic heterogeneity and Fluorescence in situ hybridization. His studies deal with areas such as Biophysics, Tissue Array Analysis and In situ hybridization as well as Fluorescence in situ hybridization.

Between 2010 and 2019, his most popular works were:

  • Genetic variegation of clonal architecture and propagating cells in leukaemia (644 citations)
  • Single cell mutational profiling and clonal phylogeny in cancer (98 citations)
  • Genetic and functional diversity of propagating cells in glioblastoma (47 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Mutation

Lyndal Kearney mostly deals with Genetics, Genomics, Cancer stem cell, Genetic variation and Targeted therapy. His is involved in several facets of Genetics study, as is seen by his studies on Neuroblastoma RAS viral oncogene homolog, Stem cell, Variegation, DNA profiling and Antibody. The study incorporates disciplines such as Gene rearrangement, Nonsynonymous substitution and Exome in addition to Neuroblastoma RAS viral oncogene homolog.

The study incorporates disciplines such as Cancer cell, Fluorescence in situ hybridization, Genetic heterogeneity and Genetic architecture in addition to Variegation. His Antibody study combines topics from a wide range of disciplines, such as Fusion gene, Gene, Leukemia and T-cell receptor. The concepts of his Leukemia study are interwoven with issues in Phenotype, Lineage and Haematopoiesis.

Best Publications

  • Genetic variegation of clonal architecture and propagating cells in leukaemia

    Kristina Anderson;Christoph Lutz;Frederik W. van Delft;Caroline M. Bateman

  • Deregulated expression of cytokine receptor gene, CRLF2 , is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia

    Lisa J. Russell;Melania Capasso;Inga Vater;Takashi Akasaka

  • Subtle chromosomal rearrangements in children with unexplained mental retardation.

    Samantha J L Knight;Regina Regan;Alison Nicod;Sharon W Horsley

  • Narrowing and genomic annotation of the commonly deleted region of the 5q syndrome

    Jacqueline Boultwood;Carrie Fidler;Amanda J. Strickson;Fiona Watkins

  • A complete set of human telomeric probes and their clinical application

    Yi Ning;Anna Roschke;Ann C.M. Smith;Ann C.M. Smith;Michelle Macha;Michelle Macha

  • A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia.

    Rina J. Jaju;Carrie Fidler;Oskar A. Haas;Amanda J. Strickson

  • A Comprehensive Screen for TWIST Mutations in Patients with Craniosynostosis Identifies a New Microdeletion Syndrome of Chromosome Band 7p21.1

    David Johnson;Sharon W. Horsley;Dominique M. Moloney;Michael Oldridge

  • Development and clinical application of an innovative fluorescence in situ hybridization technique which detects submicroscopic rearrangements involving telomeres.

    S J Knight;S W Horsley;R Regan;N M Lawrie

  • Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia.

    Lyndal Kearney;David Gonzalez De Castro;Jenny Yeung;Julia Procter

  • Clinical and hematologic aspects of the X-linked alpha-thalassemia/mental retardation syndrome (ATR-X).

    R J Gibbons;L Brueton;V J Buckle;J Burn

  • The tyrosine kinase abl-related gene ARG is fused to ETV6 in an AML-M4Eo patient with a t(1;12)(q25;p13): molecular cloning of both reciprocal transcripts.

    Giovanni Cazzaniga;Sabrina Tosi;Sabrina Tosi;Alessandra Aloisi;Alessandra Aloisi;Giovanni Giudici;Giovanni Giudici

  • Single cell mutational profiling and clonal phylogeny in cancer

    Nicola E. Potter;Luca Ermini;Elli Papaemmanuil;Giovanni Cazzaniga

  • The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case.

    Giovanni Cazzaniga;Maria Daniotti;Sabrina Tosi;Giovanni Giudici

  • Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia

    Caroline M Bateman;Susan M Colman;Tracy Chaplin;Bryan D Young

  • Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.

    Frederik W. van Delft;Sharon Horsley;Sue Colman;Kristina Anderson

  • Chemotherapy and autografting for chronic granulocytic leukaemia in transformation: probable prolongation of survival for some patients.

    M. E. Haines;J. M. Goldman;A. M. Worsley;D. M. McCarthy

  • The impact of the new FISH technologies on the cytogenetics of haematological malignancies

    Lyndal Kearney

  • Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16

    Rachael J. Daniels;John F. Peden;Christine Lloyd;Sharon W. Horsley

  • Molecular cytogenetic delineation of the critical deleted region in the 5q- syndrome.

    Rina J. Jaju;Jacqueline Boultwood;Fiona J. Oliver;Markus Kostrzewa

  • A cryptic t(5;11)(q35;p15.5) in 2 children with acute myeloid leukemia with apparently normal karyotypes, identified by a multiplex fluorescence in situ hybridization telomere assay.

    Jill Brown;Mays Jawad;Stephen R.F. Twigg;Kaan Saracoglu

Frequent Co-Authors

Mel Greaves
Mel Greaves Institute of Cancer Research
Bryan D. Young
Bryan D. Young St Bartholomew's Hospital
Christine J. Harrison
Christine J. Harrison Newcastle University
Andrea Biondi
Andrea Biondi University of Milano-Bicocca
Jochen Harbott
Jochen Harbott University of Giessen
Samantha J.L. Knight
Samantha J.L. Knight University of Oxford
Giovanni Cazzaniga
Giovanni Cazzaniga University of Milano-Bicocca
Oskar A. Haas
Oskar A. Haas Medical University of Vienna
Jonathan Flint
Jonathan Flint University of California, Los Angeles
Anthony V. Moorman
Anthony V. Moorman Newcastle University

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