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Molecular Biology

D-Index
74
Citations
14329
World Ranking
1253
National Ranking
96

Overview

Bryan D. Young is affiliated with St Bartholomew's Hospital in the United Kingdom. Their research focuses primarily on the field of Medicine, with significant work in subfields such as Physiology, Pulmonary and Respiratory Medicine, Epidemiology, Rheumatology, and Cardiology and Cardiovascular Medicine.

Their main research topics include:

  • Sarcoidosis and Beryllium Toxicity Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Autoimmune and Inflammatory Disorders
  • Rheumatoid Arthritis Research and Therapies
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Valve Diseases and Treatments
  • Streptococcal Infections and Treatments

Bryan D. Young has contributed to numerous publications. Recent papers include:

  • Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis, 2022, Nature Communications
  • Treatment of Multiorgan Sarcoidosis With Tofacitinib, 2020, ACR Open Rheumatology
  • Non-steroidal treatment of cardiac sarcoidosis: A systematic review, 2021, IJC Heart & Vasculature
  • Multimodality Imaging in the Diagnosis of Prosthetic Valve Endocarditis: A Brief Review, 2021, Frontiers in Cardiovascular Medicine
  • Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function, 2020, Journal of Biological Chemistry

The frequent co-authors with whom Bryan D. Young has collaborated include:

  • Edward J. Miller
  • William Damsky
  • Mridu Gulati
  • Brett King
  • Alice Wang

Publications by Bryan D. Young appear in multiple venues, notably:

  • Journal of Nuclear Cardiology
  • Nature Communications
  • ACR Open Rheumatology
  • Frontiers in Cardiovascular Medicine
  • IJC Heart & Vasculature

Best Publications

  • A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias.

    Malek Djabali;Licia Selleri;Pauline Parry;Mark Bower

  • Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis.

    David P. Kelsell;Elizabeth E. Norgett;Harriet Unsworth;Muy Teck Teh

  • Replication timing of the human genome

    Kathryn Woodfine;Heike Fiegler;David M. Beare;John E. Collins

  • Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias.

    Manoj Raghavan;Debra M. Lillington;Spyros Skoulakis;Silvana Debernardi

  • Cloning of a representative genomic library of the human X chromosome after sorting by flow cytometry.

    Kay E. Davies;Bryan D. Young;Robert G. Elles;Marion E. Hill

  • Distinctive patterns of microRNA expression associated with karyotype in acute myeloid leukaemia.

    Amanda Dixon-McIver;Phil East;Charles A. Mein;Jean-Baptiste Cazier

  • Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.

    Tim Forshew;Ruth G Tatevossian;Ruth G Tatevossian;Andrew R J Lawson;Jing Ma

  • Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

    Yilong Li;Claire Schwab;Sarra L. Ryan;Elli Papaemmanuil

  • Association between acquired uniparental disomy and homozygous gene mutation in acute myeloid leukemias.

    Jude Fitzgibbon;Lan-Lan Smith;Manoj Raghavan;Matthew L. Smith

  • Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas

    Xin Mao;Guy Orchard;Debra M. Lillington;Robin Russell-Jones

  • Genome-wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events.

    Silvana Debernardi;Debra M. Lillington;Tracy Chaplin;Simon Tomlinson

  • FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation.

    Emilios Gemenetzidis;Amrita Bose;Adeel M. Riaz;Tracy Chaplin

  • Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia.

    Lyndal Kearney;David Gonzalez De Castro;Jenny Yeung;Julia Procter

  • Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

    A Ptasinska;S A Assi;D Mannari;S R James

  • Molecular cytogenetic analysis of cutaneous T-cell lymphomas: identification of common genetic alterations in Sézary syndrome and mycosis fungoides.

    Xin Mao;D Lillington;J J Scarisbrick;Tracey Mitchell

  • Genomewide Single Nucleotide Polymorphism Microarray Mapping in Basal Cell Carcinomas Unveils Uniparental Disomy as a Key Somatic Event

    Muy-Teck Teh;Diana Blaydon;Tracy Chaplin;Nicola J. Foot

  • The significance of circulating cells carrying t(14;18) in long remission from follicular lymphoma.

    C. G. A. Price;J. Meerabux;S. Murtagh;F. E. Cotter

  • Construction and characterization of genomic libraries from specific human chromosomes

    Robert Krumlauf;Marc Jeanpierre;Bryan D. Young

  • A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia

    T. Chaplin;P. Ayton;O. A. Bernard;Vaskar Saha

  • The t(10;11) Translocation in Acute Myeloid Leukemia (M5) Consistently Fuses the Leucine Zipper Motif of AF10 Onto the HRX Gene

    T Chaplin;O Bernard;O Bernard;O Bernard;HB Beverloo;HB Beverloo;HB Beverloo;V Saha;V Saha;V Saha

Frequent Co-Authors

Lyndal Kearney
Lyndal Kearney Institute of Cancer Research
Sean Whittaker
Sean Whittaker King's College London
David Oscier
David Oscier Royal Bournemouth Hospital
Mark Bower
Mark Bower Imperial College London
Daniel M. Berney
Daniel M. Berney Barts Health NHS Trust
Christine J. Harrison
Christine J. Harrison Newcastle University
Jude Fitzgibbon
Jude Fitzgibbon Queen Mary University of London
Mel Greaves
Mel Greaves Institute of Cancer Research
Andrew Collins
Andrew Collins University of Oslo
Nigel P. Carter
Nigel P. Carter Wellcome Sanger Institute

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