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Biology and Biochemistry

D-Index
62
Citations
11511
World Ranking
10976
National Ranking
784

Overview

Manfred Metzler is affiliated with the Karlsruhe Institute of Technology in Germany. Their research primarily focuses on Agricultural and Biological Sciences, with a particular emphasis on the subfields of Plant Science, Food Science, Insect Science, Health, Toxicology and Mutagenesis, and Organic Chemistry.

The scientist's recent publications cover various topics related to food safety, toxicology, and agricultural sciences. Notable papers include:

  • Risk assessment of ochratoxin A in food (2020, EFSA Journal)
  • DNA reactivity of altertoxin II: Identification of two covalent guanine adducts formed under cell-free conditions (2020, Toxicology Letters)
  • Evaluation of the risks for animal health related to the presence of hydroxymethylfurfural (HMF) in feed for honey bees (2022, EFSA Journal)
  • Assessment of an application on a detoxification process of groundnut press cake for aflatoxins by ammoniation (2021, EFSA Journal)
  • Decontamination process for dioxins and dioxin-like PCBs from fish oil and vegetable oils and fats by a physical process with activated carbon (2022, EFSA Journal)

Metzler's work spans main research topics including:

  • Mycotoxins in Agriculture and Food
  • Pesticide Residue Analysis and Safety
  • Agricultural Safety and Regulations
  • Genetically Modified Organisms Research
  • Synthesis and Biological Evaluation
  • Fungal Plant Pathogen Control
  • Insect and Pesticide Research

Frequent collaborators in their research include Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl-Kraupp, and L.A.P. Hoogenboom. These collaborations reflect interdisciplinary approaches within the fields of toxicology, food safety, and agricultural sciences.

The scientist's publications are predominantly found in the EFSA Journal, with five papers, followed by Toxicology Letters and Archives of Toxicology. These venues indicate a specialization in food safety, toxicological research, and regulatory sciences.

Best Publications

  • The estrogenicity of bisphenol A-related diphenylalkanes with various substituents at the central carbon and the hydroxy groups.

    Pilar Perez;Rosa Pulgar;Fatima Olea-Serrano;Mercedes Villalobos

  • Oxidative metabolism of the soy isoflavones daidzein and genistein in humans in vitro and in vivo.

    Sabine E. Kulling;Doris M. Honig;Manfred Metzler

  • Curcumin uptake and metabolism

    Manfred Metzler;Erika Pfeiffer;Simone I. Schulz;Julia S. Dempe

  • Risk assessment of ochratoxin A in food

    Dieter Schrenk;Laurent Bodin;James Kevin Chipman

  • Estrogenic and clastogenic potential of the mycotoxin alternariol in cultured mammalian cells.

    L Lehmann;J Wagner;M Metzler

  • Metabolism of Curcuminoids in Tissue Slices and Subcellular Fractions from Rat Liver

    Simone I. Hoehle;Erika Pfeiffer;and Anikó M. Sólyom;Manfred Metzler

  • Identification and stereochemical characterization of lignans in flaxseed and pumpkin seeds.

    Tina Sicilia;Heike B Niemeyer;Doris M Honig;Manfred Metzler

  • Mutagenicity of the mycotoxin alternariol in cultured mammalian cells.

    Eva-Maria Brugger;Jörg Wagner;David M. Schumacher;Karen Koch

  • Zearalenone and its metabolites as endocrine disrupting chemicals

    M. Metzler;E. Pfeiffer;A. A. Hildebrand

  • Total synthesis of alternariol.

    Karen Koch;Joachim Podlech;Erika Pfeiffer;Manfred Metzler

  • Electrophilic Properties of Patulin. N-Acetylcysteine and Glutathione Adducts

    Ralph Fliege;Manfred Metzler

  • Erucic acid in feed and food

    Helle Katrine Knutsen;Jan Alexander;Lars Barregård;Margherita Bignami

  • Interference with microtubules and induction of micronuclei in vitro by various bisphenols

    Erika Pfeiffer;Brigitte Rosenberg;Susanne Deuschel;Manfred Metzler

  • Oxidative in Vitro Metabolism of the Soy Phytoestrogens Daidzein and Genistein

    Sabine E. Kulling;Doris M. Honig;Thomas J. Simat;Manfred Metzler

  • Alternaria toxins: Altertoxin II is a much stronger mutagen and DNA strand breaking mycotoxin than alternariol and its methyl ether in cultured mammalian cells.

    Stefanie C. Fleck;Britta Burkhardt;Erika Pfeiffer;Manfred Metzler

  • Oxidative metabolism and genotoxic potential of major isoflavone phytoestrogens.

    Sabine E Kulling;Leane Lehmann;Manfred Metzler

  • Metabolites of diethylstilboestrol induce sister chromatid exchange in human cultured fibroblasts

    H W Rüdiger;F Haenisch;M Metzler;F Oesch

  • Alternaria toxins: DNA strand-breaking activity in mammalian cellsin vitro.

    E. Pfeiffer;S. Eschbach;M. Metzler

  • Mutagenicity of the mycotoxin patulin in cultured Chinese hamster V79 cells, and its modulation by intracellular glutathione

    David M. Schumacher;Manfred Metzler;Leane Lehmann

  • Appropriateness to set a group health based guidance value for nivalenol and its modified forms

    Helle Katrine Knutsen;Lars Barregård;Margherita Bignami

Frequent Co-Authors

Christer Hogstrand
Christer Hogstrand King's College London
Bettina Grasl-Kraupp
Bettina Grasl-Kraupp Medical University of Vienna
Margherita Bignami
Margherita Bignami Istituto Superiore di Sanità
Sandra Ceccatelli
Sandra Ceccatelli Karolinska Institute
Lutz Edler
Lutz Edler German Cancer Research Center
Jan Alexander
Jan Alexander Norwegian Institute of Public Health
Isabelle P. Oswald
Isabelle P. Oswald Federal University of Toulouse Midi-Pyrénées
Chiara Dall’Asta
Chiara Dall’Asta University of Parma
Arno C. Gutleb
Arno C. Gutleb Wageningen University & Research
Reinhard Fischer
Reinhard Fischer Karlsruhe Institute of Technology

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