Her primary scientific interests are in DNA repair, Molecular biology, DNA damage, DNA mismatch repair and Genetics. The various areas that Margherita Bignami examines in her DNA repair study include Cell cycle, Cancer research and Cell biology. Her Molecular biology research includes themes of DNA glycosylase, Genome instability and Proliferating cell nuclear antigen.
Her work in DNA damage covers topics such as DNA polymerase which are related to areas like Frameshift mutation, Transversion, DNA polymerase beta, Homologous recombination and RAD51. Her DNA mismatch repair study is associated with DNA. Her Genetics research focuses on Microsatellite instability in particular.
Her main research concerns Molecular biology, Genetics, DNA repair, DNA and DNA mismatch repair. Her Molecular biology research focuses on Mutation and how it connects with Carcinogen. As part of her studies on DNA repair, Margherita Bignami often connects relevant subjects like Cell cycle.
Her work in DNA tackles topics such as Oxidative stress which are related to areas like Nucleotide. Margherita Bignami combines subjects such as 8-Oxoguanine, Cancer research, Chemotherapy, Microsatellite instability and Acute leukemia with her study of DNA mismatch repair. Her studies examine the connections between DNA replication and genetics, as well as such issues in Werner syndrome, with regards to Werner Syndrome Helicase.
Margherita Bignami mostly deals with Risk assessment, Toxicology, Animal science, Mink and European commission. Her Toxicology study combines topics from a wide range of disciplines, such as Younger age, Exposure assessment, Lupinus luteus and Aflatoxin. Her Animal science research integrates issues from No-observed-adverse-effect level, Cottonseed and Micronucleus test.
Margherita Bignami has included themes like Toxicity and Fusarium in her Mycotoxin study. DNA repair is a subfield of DNA that she tackles. Her DNA study introduces a deeper knowledge of Genetics.
Her primary areas of study are Risk assessment, Human health, Toxicology, Body weight and Mink. Her Toxicology study incorporates themes from Younger age, Food additive, Incidence and Potency. Her Body weight research incorporates themes from Fishery and Tetrodotoxin.
Mink combines with fields such as Epidemiology, Toxicity, Mycotoxin, Fusarium and Animal science in her work. The Epidemiology study combines topics in areas such as Breastfeeding, Adverse effect and Forage. Margherita Bignami interconnects Zearalenone and Zearalanone in the investigation of issues within Toxicity.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The Mammalian Mismatch Repair Pathway Removes DNA 8-oxodGMP Incorporated from the Oxidized dNTP Pool
Claudia Colussi;Eleonora Parlanti;Paolo Degan;Gabriele Aquilina.
Current Biology (2002)
The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells.
Maria Teresa Russo;Monica Francesca Blasi;Federica Chiera;Paola Fortini.
Molecular and Cellular Biology (2004)
Accumulation of the Oxidative Base Lesion 8-Hydroxyguanine in DNA of Tumor-Prone Mice Defective in Both the Myh and Ogg1 DNA Glycosylases
Maria Teresa Russo;Gabriele De Luca;Paolo Degan;Eleonora Parlanti.
Cancer Research (2004)
Risks for human health related to the presence of 3- and 2-monochloropropanediol (MCPD), and their fatty acid esters, and glycidyl fatty acid esters in food
Heather Wallace;Alexander Jan;Lars Barregård;Margherita Bignami.
EFSA Journal (2016)
Risks to human and animal health related to the presence of deoxynivalenol and its acetylated and modified forms in food and feed
Helle Katrine Knutsen;Jan Alexander;Lars Barregård;Margherita Bignami.
EFSA Journal (2017)
ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery.
Francesca Ammazzalorso;Livia Maria Pirzio;Margherita Bignami;Annapaola Franchitto.
The EMBO Journal (2010)
Different DNA repair strategies to combat the threat from 8-oxoguanine.
Maria Teresa Russo;Gabriele De Luca;Paolo Degan;Margherita Bignami.
Mutation Research (2007)
Risk to human health related to the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food
Helle Katrine Knutsen;Jan Alexander;Lars Barregård;Margherita Bignami.
EFSA Journal (2018)
Werner syndrome helicase activity is essential in maintaining fragile site stability.
Livia Maria Pirzio;Pietro Pichierri;Margherita Bignami;Annapaola Franchitto.
Journal of Cell Biology (2008)
Mismatch repair in correction of replication errors and processing of DNA damage.
Gabriele Aquilina;Margherita Bignami.
Journal of Cellular Physiology (2001)
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