2026 Carolyn A. Felix: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	52	2438	2197	1200	1070	132	9904

Overview

Carolyn A. Felix is affiliated with the Children's Hospital of Philadelphia in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology as well as medicine. Within these broad areas, their work spans key subfields including molecular biology, public health, environmental and occupational health, immunology, hematology, and genetics.

The scientist's research topics cover a range of areas related to cellular and molecular mechanisms, particularly in disease contexts. Main topics include:

Acute lymphoblastic leukemia research
RNA modifications and cancer
Biochemical and molecular research
Epigenetics and DNA methylation
Immune cell function and interaction
Hematopoietic stem cell transplantation
Genetics and neurodevelopmental disorders

Carolyn A. Felix has contributed to several recent publications that provide insight into disease mechanisms and genetic factors. Notable papers include:

"Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia," 2021, Blood
"Expanding the genotypic and phenotypic spectrum in a diverse cohort of 104 individuals with Wiedemann-Steiner syndrome," 2021, American Journal of Medical Genetics Part A
"Leukemia-associated transcription factor mllt3 is important for primitive erythroid development in zebrafish embryogenesis," 2022, Developmental Dynamics
"KMT2A partner genes in infant acute lymphoblastic leukemia have prognostic significance and correlate with age, white blood cell count, sex, and central nervous system involvement: a Children's Oncology Group P9407 trial study," 2023, Haematologica
"Expanding the genotypic and phenotypic spectrum in a diverse cohort of 104 individuals with Wiedemann-Steiner Syndrome," 2021, Molecular Genetics and Metabolism

Their frequent co-authors include Patrizia Porazzi, J. W. Davenport, Stephen P. Hunger, Sarah E. Sheppard, and Ian M. Campbell. These collaborative relationships emphasize interdisciplinary approaches across genetics, hematology, and clinical research.

Common venues for publication reflect the scientist's focus on hematology, genetics, and molecular medicine. These journals include Blood, American Journal of Medical Genetics Part A, Developmental Dynamics, Haematologica, and Molecular Genetics and Metabolism.

Best Publications

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

W.-J. Song;M. G. Sullivan;R. D. Legare;S. Hutchings

1255
Citations
SECONDARY LEUKEMIAS INDUCED BY TOPOISOMERASE-TARGETED DRUGS

Carolyn A. Felix

559
Citations
High incidence of secondary brain tumours after radiotherapy and antimetabolites

Mary V. Relling;Mary V. Relling;Jeffrey E. Rubnitz;Jeffrey E. Rubnitz;Gaston K. Rivera;Gaston K. Rivera;James M. Boyett;James M. Boyett

528
Citations
Association of CYP3A4 genotype with treatment-related leukemia

Carolyn A. Felix;Amy H. Walker;Beverly J. Lange;Terence M. Williams

443
Citations
The Molecular Basis of Leukemia

D. Gary Gilliland;Craig T. Jordan;Carolyn A. Felix

438
Citations
DNA Topoisomerase II in Therapy-Related Acute Promyelocytic Leukemia

Anita R. Mistry;Carolyn A. Felix;Ryan J. Whitmarsh;Annabel Mason

343
Citations
Leukemias related to treatment with DNA topoisomerase II inhibitors.

Carolyn A. Felix

263
Citations
Frequency and Diversity of p53 Mutations in Childhood Rhabdomyosarcoma

Carolyn A. Felix;Cynthia Chavez Kappel;Tetsuya Mitsudomi;Marion M. Nau

236
Citations
Maternal Diet and Infant Leukemia: The DNA Topoisomerase II Inhibitor Hypothesis: A Report from the Children's Oncology Group

Logan G. Spector;Yang Xie;Leslie L. Robison;Nyla A. Heerema

234
Citations
Topoisomerase II and leukemia

MaryJean Pendleton;R. Hunter Lindsey;Carolyn A. Felix;David Grimwade

231
Citations
t(11;22)(q23;q11.2) in acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes

Maureen D. Megonigal;Eric F. Rappaport;Douglas H. Jones;Terence M. Williams

223
Citations
Topoisomerase II and the etiology of chromosomal translocations.

Carolyn A. Felix;Christos P. Kolaris;Neil Osheroff

202
Citations
ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children

Carolyn A. Felix;Matthew R. Hosler;Naomi J. Winick;Margaret Masterson

183
Citations
Chromosome Band 11q23 Translocation Breakpoints Are DNA Topoisomerase II Cleavage Sites

Carolyn A. Felix;Beverly J. Lange;Matthew R. Hosler;Jolanta Fertala

155
Citations
1,4-Benzoquinone is a topoisomerase II poison.

R. Hunter Lindsey;Kenneth D. Bromberg;Carolyn A. Felix;Neil Osheroff

148
Citations
The t(11;20)(p15;q11) chromosomal translocation associated with therapy-related myelodysplastic syndrome results in an NUP98-TOP1 fusion.

Harish G. Ahuja;Carolyn A. Felix;Carolyn A. Felix;Carolyn A. Felix;Peter D. Aplan;Peter D. Aplan;Peter D. Aplan

148
Citations
Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: A Children's Oncology Group study.

Huining Kang;Carla S. Wilson;Richard C. Harvey;I. Ming Chen;I. Ming Chen

147
Citations
Potential topoisomerase II DNA-binding sites at the breakpoints of a t(9;11) chromosome translocation in acute myeloid leukemia

M. Negrini;C. A. Felix;C. Martin;B. J. Lange

137
Citations
Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion.

Jolanta Libura;Diana J. Slater;Diana J. Slater;Diana J. Slater;Carolyn A. Felix;Carolyn A. Felix;Carolyn A. Felix;Christine Richardson;Christine Richardson;Christine Richardson

133
Citations
Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

Maureen D. Megonigal;Nai-Kong V. Cheung;Eric F. Rappaport;Peter C. Nowell

131
Citations

Frequent Co-Authors

Beverly J. Lange Children's Hospital of Philadelphia

Eric F. Rappaport Children's Hospital of Philadelphia

Neil Osheroff Vanderbilt University

Peter C. Nowell University of Pennsylvania

Stephen P. Hunger University of Pennsylvania

Cheryl L. Willman University of New Mexico

Naomi J. Winick The University of Texas Southwestern Medical Center

Nyla A. Heerema The Ohio State University

Andrew J. Carroll University of Alabama at Birmingham

Ian A. Blair University of Pennsylvania

External Links

Personal website of Carolyn A. Felix

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