World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
105
Citations
44036
World Ranking
6733
National Ranking
3553

C. David James publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where C. David James sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 359 publications — 30th percentile

30% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

C. David James D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where C. David James sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 105 D-Index — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

C. David James is affiliated with Northwestern University in the United States. Their research spans the fields of biochemistry, genetics, molecular biology, and medicine, with a focused expertise in molecular biology, genetics, immunology, oncology, and neurology.

The scientist's work covers several main topics, including:

  • Glioma diagnosis and treatment
  • Immune cells in cancer
  • Neuroinflammation and neurodegeneration mechanisms
  • Epigenetics and DNA methylation
  • CAR-T cell therapy research
  • Histone deacetylase inhibitors research
  • Cancer research and treatments

Frequent co-authors collaborating with C. David James include:

  • Craig Horbinski
  • Amy B. Heimberger
  • Maciej S. Lesniak
  • Hinda Najem
  • Atique U. Ahmed

The scientist has published extensively in several venues, with the most frequent including:

  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • Clinical Cancer Research
  • Cancers

Recent papers authored by C. David James demonstrate involvement in clinical and molecular cancer research, particularly related to glioblastoma and cancer resistance mechanisms. Notable publications include:

  • "A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma," 2021, Science Translational Medicine
  • "Context-Dependent Glioblastoma-Macrophage/Microglia Symbiosis and Associated Mechanisms," 2021, Trends in Immunology
  • "PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells," 2021, Molecular Cell
  • "Review of gas emissions from lithium-ion battery thermal runaway failure - Considering toxic and flammable compounds," 2024, Journal of Energy Storage
  • "De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma," 2021, Brain

Best Publications

  • Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

    Roel G. W. Verhaak;Katherine A. Hoadley;Elizabeth Purdom;Victoria Wang

  • miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.

    Joachim Silber;Daniel A Lim;Claudia Petritsch;Anders I Persson

  • Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas.

    Lori Frederick;Xiao Yang Wang;Greg Eley;C. David James

  • PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.

    Justin S. Smith;Issei Tachibana;Sandra M. Passe;Brenda K. Huntley

  • Sporadic Medulloblastomas Contain PTCH Mutations

    Corey Raffel;Robert B. Jenkins;Lori Frederick;Deanne Hebrink

  • The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression.

    Kui Ming Chan;Dong Fang;Haiyun Gan;Rintaro Hashizume

  • A hierarchy of self-renewing tumor-initiating cell types in glioblastoma

    Ruihuan Chen;Merry C. Nishimura;Stephanie M. Bumbaca;Samir Kharbanda

  • Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.

    David A. Nathanson;Beatrice Gini;Jack Mottahedeh;Koppany Visnyei

  • Mutational Inactivation of STAG2 Causes Aneuploidy in Human Cancer

    David A. Solomon;Taeyeon Kim;Laura A. Diaz-Martinez;Joshlean Fair

  • Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

    Albert Lai;Samir Kharbanda;Whitney B. Pope;Anh Tran

  • Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma

    Rintaro Hashizume;Noemi Andor;Yuichiro Ihara;Robin Lerner

  • An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR–Dependent Pathway

    Deliang Guo;Felicia Reinitz;Mary Youssef;Cynthia Hong

  • Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

    Andrea Piunti;Rintaro Hashizume;Marc A. Morgan;Elizabeth T. Bartom

  • Mechanisms of Chemoresistance to Alkylating Agents in Malignant Glioma

    Jann N. Sarkaria;Gaspar J. Kitange;C. David James;Ruth Plummer

  • An overview of meningiomas.

    Robin A Buerki;Craig M Horbinski;Timothy Kruser;Peleg M Horowitz

  • Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

    Michael D. Prados;Susan M. Chang;Nicholas Butowski;Rebecca DeBoer

  • Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts

    Gaspar J. Kitange;Brett L. Carlson;Mark A. Schroeder;Patrick T. Grogan

  • Epidermal Growth Factor Receptor Variant III Status Defines Clinically Distinct Subtypes of Glioblastoma

    Christopher E. Pelloski;Karla V. Ballman;Alfred F. Furth;Li Zhang

  • Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations

    Wanguo Liu;David I. Smith;Keri J. Rechtzigel;Stephen N. Thibodeau

  • Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme.

    Caterina Giannini;Jann N. Sarkaria;Atsushi Saito;Joon H. Uhm

Frequent Co-Authors

Craig Horbinski
Craig Horbinski Northwestern University
Mitchel S. Berger
Mitchel S. Berger University of California, San Francisco
Michael D. Prados
Michael D. Prados University of California, San Francisco
Jann N. Sarkaria
Jann N. Sarkaria Mayo Clinic
Joanna J. Phillips
Joanna J. Phillips University of California, San Francisco
Atique U. Ahmed
Atique U. Ahmed Northwestern University
Nalin Gupta
Nalin Gupta University of California, San Francisco
Scott R. VandenBerg
Scott R. VandenBerg University of California, San Francisco
Shi Yuan Cheng
Shi Yuan Cheng Northwestern University

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