Member of the Association of American Physicians
His main research concerns Cancer research, Pathology, Glioma, Internal medicine and Astrocytoma. His Cancer research study combines topics in areas such as Gene expression, DNA methylation, Bioinformatics, Carcinogenesis and Transcription factor. His research in DNA methylation intersects with topics in Cancer Genome Project, DNA mismatch repair, Functional genomics and ATRX.
Daniel J. Brat interconnects Angiogenesis, Central nervous system disease and Anatomy in the investigation of issues within Pathology. Daniel J. Brat has researched Glioma in several fields, including In vivo, Hypoxia and IDH1. His Internal medicine research is multidisciplinary, relying on both Endocrinology, Oncology and PAS domain.
Daniel J. Brat mainly focuses on Pathology, Cancer research, Glioma, Internal medicine and Brain tumor. CDKN2A is closely connected to Astrocytoma in his research, which is encompassed under the umbrella topic of Pathology. While the research belongs to areas of Cancer research, he spends his time largely on the problem of DNA methylation, intersecting his research to questions surrounding ATRX.
The concepts of his Glioma study are interwoven with issues in Cancer and Stem cell. His Stem cell research integrates issues from Asymmetric cell division and Cyclin-dependent kinase 5. His Internal medicine study combines topics from a wide range of disciplines, such as Endocrinology and Oncology.
His primary scientific interests are in Cancer research, Glioma, Pathology, Artificial intelligence and Brain tumor. His work on Glioblastoma as part of general Cancer research research is frequently linked to OLIG2, thereby connecting diverse disciplines of science. His studies deal with areas such as Cancer, Internal medicine, Radiation therapy and Oncology as well as Glioma.
His Oncology research incorporates elements of Oligodendroglioma and DNA methylation. Daniel J. Brat frequently studies issues relating to Solitary fibrous tumor and Pathology. His biological study deals with issues like Third ventricle, which deal with fields such as Neurology, Coagulative necrosis and Tumor progression.
Daniel J. Brat focuses on Cancer research, Glioma, Brain tumor, Oncology and Internal medicine. Daniel J. Brat has included themes like Oncogene, Transcription factor, Signal transduction, microRNA and PTEN in his Cancer research study. His microRNA research is multidisciplinary, incorporating perspectives in Mutation rate and DNA methylation.
Daniel J. Brat combines subjects such as Phenotype, Magnetic resonance imaging, Kinase and Proteomics with his study of Glioma. His Oncology research includes elements of Cancer, Anaplastic astrocytoma, Diffuse Astrocytoma, Not Otherwise Specified and Oligodendroglioma. The study incorporates disciplines such as Lesion, Astrocytoma, Astrocytic glioma and Human glioma in addition to Internal medicine.
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir.
Nature (2008)
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung.
The New England Journal of Medicine (2015)
Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.
Michele Ceccarelli;Floris P Barthel;Tathiane M Malta;Thais S Sabedot.
Cell (2016)
The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
Daniel J. Brat;Anita C. Bellail;Erwin G. Van Meir.
Neuro-oncology (2005)
Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis
Balveen Kaur;Fatima W. Khwaja;Eric A. Severson;Shannon L. Matheny.
Neuro-oncology (2005)
Transforming fusions of FGFR and TACC genes in human glioblastoma
Devendra Singh;Joseph Minhow Chan;Pietro Zoppoli;Francesco Niola;Francesco Niola.
Science (2012)
International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading
David N. Louis;Arie Perry;Peter Burger;David W. Ellison.
Brain Pathology (2014)
Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion.
Anita C Bellail;Stephen B Hunter;Daniel J Brat;Chalet Tan.
The International Journal of Biochemistry & Cell Biology (2004)
Predicting cancer outcomes from histology and genomics using convolutional networks
Pooya Mobadersany;Safoora Yousefi;Mohamed Amgad;David A. Gutman.
Proceedings of the National Academy of Sciences of the United States of America (2018)
'Pseudopalisading' necrosis in glioblastoma: A familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis
Yuan Rong;Donald L. Durden;Erwin G. Van Meir;Daniel J. Brat.
Journal of Neuropathology and Experimental Neurology (2006)
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