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Medicine

D-Index
112
Citations
79776
World Ranking
5046
National Ranking
2732

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Daniel J. Brat is affiliated with Northwestern University in the United States. Their research primarily spans the field of medicine with a focus on genetics, molecular biology, pulmonary and respiratory medicine, neurology, and cancer research.

Their work covers several key topics including:

  • Glioma Diagnosis and Treatment
  • Brain Metastases and Treatment
  • Immune cells in cancer
  • Meningioma and schwannoma management
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer, Hypoxia, and Metabolism
  • Neuroblastoma Research and Treatments

Brat's frequent collaborators include Karen Fritchie, Rhonda K. Yantiss, David Kaminsky, Zubair Baloch, and Sarah Dry. They have published extensively in several venues, most often in:

  • Neuro-Oncology
  • Modern Pathology
  • Laboratory Investigation
  • Acta Neuropathologica
  • Journal of Neuropathology & Experimental Neurology

Among Brat's recent papers are the following:

  • "The 2021 WHO Classification of Tumors of the Central Nervous System: a summary," 2021, Neuro-Oncology
  • "cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading," 2020, Brain Pathology
  • "cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas," 2020, Acta Neuropathologica
  • "Glioma progression is shaped by genetic evolution and microenvironment interactions," 2022, Cell
  • "A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma," 2021, Science Translational Medicine

They hold the distinction of being a member of the Association of American Physicians.

Best Publications

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • The 2021 WHO Classification of Tumors of the Central Nervous System: a summary.

    David N Louis;Arie Perry;Pieter Wesseling;Daniel J Brat

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.

    Michele Ceccarelli;Floris P Barthel;Tathiane M Malta;Thais S Sabedot

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Predicting cancer outcomes from histology and genomics using convolutional networks

    Pooya Mobadersany;Safoora Yousefi;Mohamed Amgad;David A. Gutman

  • The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis

    Daniel J. Brat;Anita C. Bellail;Erwin G. Van Meir

  • Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.

    André Kahles;Kjong-Van Lehmann;Nora C Toussaint;Matthias Hüser

  • Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

    Balveen Kaur;Fatima W. Khwaja;Eric A. Severson;Shannon L. Matheny

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • cIMPACT-NOW Update 3: Recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”

    Daniel J. Brat;Kenneth Aldape;Howard Colman;Eric C. Holland

  • Transforming fusions of FGFR and TACC genes in human glioblastoma

    Devendra Singh;Joseph Minhow Chan;Pietro Zoppoli;Francesco Niola;Francesco Niola

  • International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading

    David N. Louis;Arie Perry;Peter Burger;David W. Ellison

  • 'Pseudopalisading' necrosis in glioblastoma: A familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis

    Yuan Rong;Donald L. Durden;Erwin G. Van Meir;Daniel J. Brat

  • Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion.

    Anita C Bellail;Stephen B Hunter;Daniel J Brat;Chalet Tan

  • Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups

    David W. Ellison;James Dalton;Mehmet Kocak;Sarah Leigh Nicholson

Frequent Co-Authors

Lee Cooper
Lee Cooper Northwestern University
Jeffrey J. Olson
Jeffrey J. Olson Emory University
Erwin G. Van Meir
Erwin G. Van Meir University of Alabama at Birmingham
Arie Perry
Arie Perry University of California, San Francisco
Jill S. Barnholtz-Sloan
Jill S. Barnholtz-Sloan Case Western Reserve University
Joel H. Saltz
Joel H. Saltz Stony Brook University
Fusheng Wang
Fusheng Wang Stony Brook University
Peter C. Burger
Peter C. Burger Johns Hopkins University
Tahsin Kurc
Tahsin Kurc Stony Brook University
Carlos S. Moreno
Carlos S. Moreno Emory University

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