World's Best Scientists 2026 revealed!
Thomas Aigner

Thomas Aigner

D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
28342
World Ranking
2126
National Ranking
151

Medicine

D-Index
91
Citations
25251
World Ranking
11908
National Ranking
645

Overview

Thomas Aigner is affiliated with Leipzig University in Germany and conducts research primarily in the field of Medicine. Their work spans several subfields including Surgery, Pulmonary and Respiratory Medicine, Rheumatology, Oncology, and Molecular Biology.

Their research focuses on topics such as:

  • Osteoarthritis Treatment and Mechanisms
  • Esophageal Cancer Research and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Management of metastatic bone disease
  • Colorectal and Anal Carcinomas
  • Bone Metabolism and Diseases
  • TGF-β signaling in diseases

Some of the recent publications by Thomas Aigner include:

  • "Regulation of Gdf5 expression in joint remodelling, repair and osteoarthritis" (2020), published in Scientific Reports
  • "ROR2 blockade as a therapy for osteoarthritis" (2020), published in Science Translational Medicine
  • "Cytotoxic and immunosuppressive inflammatory cells predict regression and prognosis following neoadjuvant radiochemotherapy of oesophageal adenocarcinoma" (2020), published in Radiotherapy and Oncology
  • "PD-1 and PD-L1 expression predict regression and prognosis following neoadjuvant radiochemotherapy of oesophageal adenocarcinoma" (2022), published in Clinical and Translational Radiation Oncology
  • "Spinal and cervical nodal metastases in a patient with glioblastoma" (2024), published in Strahlentherapie und Onkologie

Frequent co-authors with whom Thomas Aigner has collaborated include:

  • Gerhard G. Grabenbauer
  • Francesco Dell'Accio
  • Luitpold Distel
  • Anne-Sophie Thorup
  • Danielle Strachan

The most common venues where Thomas Aigner's work appears are:

  • Strahlentherapie und Onkologie
  • Osteoarthritis and Cartilage
  • Scientific Reports
  • Science Translational Medicine
  • Radiotherapy and Oncology

Best Publications

  • Collagens—structure, function, and biosynthesis

    K Gelse;E Pöschl;T Aigner

  • Articular cartilage and changes in Arthritis: Cell biology of osteoarthritis

    Linda J Sandell;Thomas Aigner

  • Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice

    Karoliina Pelttari;Anja Winter;Eric Steck;Katrin Goetzke

  • Histological assessment of cartilage repair: a report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS).

    Pierre Mainil-Varlet;Thomas Aigner;Mats Brittberg;Peter Bullough

  • Oxygen and reactive oxygen species in cartilage degradation: friends or foes?

    Yves Henrotin;B. Kurz;Thomas Aigner

  • Human laminin β2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities

    Martin Zenker;Thomas Aigner;Olaf Wendler;Tim Tralau

  • Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro

    Brigitte Bau;Pia M. Gebhard;Jochen Haag;Thomas Knorr

  • Basic methods in histopathology of joint tissues.

    N. Schmitz;S. Laverty;V.B. Kraus;T. Aigner

  • Anabolic and catabolic gene expression pattern analysis in normal versus osteoarthritic cartilage using complementary DNA-array technology.

    Thomas Aigner;Alexander Zien;Angelika Gehrsitz;Pia Margarethe Gebhard

  • Large‐scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis

    Thomas Aigner;Katrin Fundel;Joachim Saas;Pia M. Gebhard

  • Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritic human articular knee cartilage: A study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee cartilage

    T. Aigner;M. Hemmel;D. Neureiter;P. M. Gebhard

  • Transplantation of allograft chondrocytes embedded in agarose gel into cartilage defects of rabbits

    B. Rahfoth;J. Weisser;F. Sternkopf;T. Aigner

  • Collagens—major component of the physiological cartilage matrix, major target of cartilage degeneration, major tool in cartilage repair

    T Aigner;J Stöve

  • Mechanisms of Disease: role of chondrocytes in the pathogenesis of osteoarthritis—structure, chaos and senescence

    Thomas Aigner;Stefan Söder;Pia M Gebhard;Audrey McAlinden

  • Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage.

    T Aigner;W Bertling;H Stöss;G Weseloh

  • Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells.

    Kolja Gelse;Klaus von der Mark;Thomas Aigner;Jung Park

  • Immunolocalization of type X collagen in normal fetal and adult osteoarthritic cartilage with monoclonal antibodies

    Girkontaite I;Frischholz S;Lammi P;Wagner K

  • Apoptosis and cellular vitality: Issues in osteoarthritic cartilage degeneration

    T. Aigner;H. A. Kim

  • Reexpression of type IIA procollagen by adult articular chondrocytes in osteoarthritic cartilage.

    Thomas Aigner;Yong Zhu;Howard H. Chansky;Frederick A. Matsen

  • Choice behavior in rhesus monkeys: cocaine versus food

    Thomas G. Aigner;Robert L. Balster

Frequent Co-Authors

Carl P. Blobel
Carl P. Blobel Cornell University
Mary B. Goldring
Mary B. Goldring Hospital for Special Surgery
Virginia B. Kraus
Virginia B. Kraus Duke University
Joachim R. Kalden
Joachim R. Kalden University of Erlangen-Nuremberg
Klaus von der Mark
Klaus von der Mark University of Erlangen-Nuremberg
Kerstin Amann
Kerstin Amann University of Erlangen-Nuremberg
Augustinus Bader
Augustinus Bader Leipzig University
Anita Rauch
Anita Rauch University of Zurich
Martin Zenker
Martin Zenker Otto-von-Guericke University Magdeburg
André Reis
André Reis University of Erlangen-Nuremberg

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