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D-Index
41
Citations
6236
World Ranking
7892
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467

Overview

Brian E. Cairns is affiliated with the University of British Columbia in Canada and has published extensively in the field of medicine, with a focus on physiology, neurology, complementary and manual therapy, psychiatry and mental health, and rheumatology. Their research contributes to understanding pain mechanisms, temporomandibular joint disorders, botulinum toxin and related neurological disorders, and migraine and headache studies.

Their recent publications include:

  • Sex-Specific Pharmacotherapy for Migraine: A Narrative Review (2020), Frontiers in Neuroscience
  • The Contribution of Autonomic Mechanisms to Pain in Temporomandibular Disorders: A Narrative Review (2022), Journal of Oral Rehabilitation
  • Sex-related Differences in Response to Masseteric Injections of Glutamate and Nerve Growth Factor in Healthy Human Participants (2021), Scientific Reports
  • Density of Nerve Fibres and Expression of Substance P, NR2B-Receptors and Nerve Growth Factor in Healthy Human Masseter Muscle: An Immunohistochemical Study (2020), Journal of Oral Rehabilitation
  • Topical Diclofenac vs Placebo for the Treatment of Chronic Achilles Tendinopathy: A Randomized Controlled Clinical Trial (2021), PLoS ONE

Frequent co-authors in their work include:

  • Peter Svensson
  • Abdelrahman M. Alhilou
  • Akiko Shimada
  • Camilla I. Svensson
  • Malin Ernberg

Brian E. Cairns has published mainly in the following venues:

  • Scientific Reports
  • Journal of Oral Rehabilitation
  • Pain
  • Frontiers in Neuroscience
  • PLoS ONE

Their primary fields of study comprise medicine, with subfields in physiology, neurology, complementary and manual therapy, psychiatry and mental health, and rheumatology. The main topics covered by their research include:

  • Pain Mechanisms and Treatments
  • Temporomandibular Joint Disorders
  • Botulinum Toxin and Related Neurological Disorders
  • Migraine and Headache Studies
  • Olfactory and Sensory Function Studies
  • Shoulder Injury and Treatment
  • Vestibular and Auditory Disorders

Best Publications

  • Pathophysiology of TMD pain – basic mechanisms and their implications for pharmacotherapy

    B. E. Cairns

  • Sex-related differences in human pain and rat afferent discharge evoked by injection of glutamate into the masseter muscle.

    Brian E. Cairns;James W. Hu;Lars Arendt-Nielsen;Barry J. Sessle

  • Injection of nerve growth factor into human masseter muscle evokes long-lasting mechanical allodynia and hyperalgesia.

    Peter Svensson;Brian Edwin Cairns;Kelun Wang;Lars Arendt-Nielsen

  • Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.

    Brian E. Cairns;Peter Svensson;Kelun Wang;Steen Hupfeld

  • Glutamate-evoked pain and mechanical allodynia in the human masseter muscle.

    Peter Svensson;Peter Svensson;Peter Svensson;Brian E Cairns;Kelun Wang;James W Hu

  • Evidence That Excitatory Amino Acid Receptors within the Temporomandibular Joint Region Are Involved in the Reflex Activation of the Jaw Muscles

    Brian E. Cairns;Barry J. Sessle;James W. Hu

  • Sex-related differences in pain

    Brian E. Cairns;Parisa Gazerani

  • Glutamate-induced sensitization of rat masseter muscle fibers.

    B.E Cairns;G Gambarota;P Svensson;P Svensson;P Svensson;L Arendt-Nielsen

  • SEX-RELATED DIFFERENCES IN NMDA-EVOKED RAT MASSETER MUSCLE AFFERENT DISCHARGE RESULT FROM ESTROGEN-MEDIATED MODULATION OF PERIPHERAL NMDA RECEPTOR ACTIVITY

    Xu-Dong Dong;Mandeep K. Mann;Ujendra Kumar;Peter Svensson

  • The influence of gender and sex steroids on craniofacial nociception.

    Brian E. Cairns

  • Characteristics of glutamate-evoked temporomandibular joint afferent activity in the rat.

    Brian E. Cairns;Barry J. Sessle;James W. Hu

  • Effects of subcutaneous administration of glutamate on pain, sensitization and vasomotor responses in healthy men and women.

    Parisa Gazerani;Kelun Wang;Brian Edwin Cairns;Peter Svensson;Peter Svensson

  • Neural Mechanisms of Temporomandibular Joint and Masticatory Muscle Pain: A Possible Role for Peripheral Glutamate Receptor Mechanisms

    David K Lam;Barry J Sessle;Brian E Cairns;James W Hu

  • Effect of systemic monosodium glutamate (MSG) on headache and pericranial muscle sensitivity

    L Baad-Hansen;BE Cairns;M Ernberg;P Svensson;P Svensson

  • Botulinum neurotoxin type A (BoNTA) decreases the mechanical sensitivity of nociceptors and inhibits neurogenic vasodilation in a craniofacial muscle targeted for migraine prophylaxis

    Parisa Gazerani;Sammy Au;Xudong Dong;Ujendra Kumar

  • Ketamine attenuates glutamate-induced mechanical sensitization of the masseter muscle in human males.

    Brian Edwin Cairns;Peter Svensson;Kelun Wang;Eduardo Castrillon

  • The effect of glutamate-evoked masseter muscle pain on the human jaw-stretch reflex differs in men and women.

    Brian E Cairns;Kelun Wang;James W Hu;Barry J Sessle

  • Pain effects of glutamate injections into human jaw or neck muscles.

    Peter Svensson;Kelun Wang;Lars Arendt-Nielsen;Brian Edwin Cairns

  • Influence of sex on reflex jaw muscle activity evoked from the rat temporomandibular joint

    Brian E Cairns;Yiin Sim;David A Bereiter;Barry J Sessle

  • Interstitial glutamate concentration is elevated in the masseter muscle of myofascial temporomandibular disorder patients.

    Eduardo E. Castrillon;Malin Ernberg;Brian Edwin Cairns;Kelun Wang

  • Cannabidiol, cannabinol and their combinations act as peripheral analgesics in a rat model of myofascial pain.

    Hayes Wong;Brian E. Cairns

Frequent Co-Authors

Lars Arendt-Nielsen
Lars Arendt-Nielsen Aalborg University
Kelun Wang
Kelun Wang Aalborg University
Barry J. Sessle
Barry J. Sessle University of Toronto
James W. Hu
James W. Hu University of Toronto
Ujendra Kumar
Ujendra Kumar University of British Columbia
Thomas Graven-Nielsen
Thomas Graven-Nielsen Aalborg University
Koichi Iwata
Koichi Iwata Nihon University
David A. Bereiter
David A. Bereiter University of Minnesota
Kenneth D. Craig
Kenneth D. Craig University of British Columbia
Daniel S. Kohane
Daniel S. Kohane Harvard Medical School

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