World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
54
Citations
9067
World Ranking
4970
National Ranking
287

Overview

James W. Hu is affiliated with the University of Toronto in Canada. Their research spans the fields of Medicine and Engineering, with a particular focus on Surgery, Pathology and Forensic Medicine, and Biomedical Engineering. Their subfields also include Molecular Biology and Radiology, Nuclear Medicine and Imaging.

The primary topics in their work involve Spine and Intervertebral Disc Pathology, Spinal Fractures and Fixation Techniques, Medical Imaging and Analysis, Monoclonal and Polyclonal Antibodies Research, vaccines and immunoinformatics approaches, Protein purification and stability, and Cardiac Structural Anomalies and Repair.

James W. Hu has published articles in several journals. Frequent publication venues include:

  • World Neurosurgery
  • mAbs
  • Journal of Medical Systems
  • Neurosurgery
  • Neurosurgical Review

Their recent papers include:

  • Systematic Review of Surgical Success, Complications, Revision Rates, Radiation Dosage, and Operative Time of 3D-Navigated versus Non-Navigated Spinal Procedures, 2024, World Neurosurgery
  • An adapted consensus protein design strategy for identifying globally optimal biotherapeutics, 2022, mAbs
  • External Ventricular Drain Placement Teleproctoring Using a Novel Camera-Projector Navigation System: A Proof-of-Concept Study, 2023, World Neurosurgery
  • Case Volume Justification of 3D-Navigated Spinal Procedures: A Cost-Benefit Analysis, 2023, Journal of Medical Systems
  • 472 Complications of 3D-Navigated Spinal Procedures: A Systematic Review, 2024, Neurosurgery

James W. Hu's frequent coauthors include:

  • Ikaasa Suri
  • Kurt Yaeger
  • S. Suthakaran
  • Daniel Kwon
  • Matthew T. Carr

Their work is notable for integrating advanced surgical techniques with medical imaging and teleproctoring technology. The research contributions cover surgical outcomes, complication rates, operative time, and cost-benefit analyses for spinal procedures using 3D navigation systems. Additionally, exploratory work in protein design and biotherapeutics is part of their portfolio.

Best Publications

  • Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses

    Donald D. Price;James W. Hu;Ronald Dubner;Richard H. Gracely

  • Convergence of cutaneous, tooth pulp, visceral, neck and muscle afferents onto nociceptive and non-nociceptive neurones in trigeminal subnucleus caudalis (medullary dorsal horn) and its implications for referred pain.

    B J Sessle;J W Hu;N Amano;G Zhong

  • Functional properties of neurons in cat trigeminal subnucleus caudalis (medullary dorsal horn). I. Responses to oral-facial noxious and nonnoxious stimuli and projections to thalamus and subnucleus oralis.

    J W Hu;J O Dostrovsky;B J Sessle

  • Stimulation of craniofacial muscle afferents induces prolonged facilitatory effects in trigeminal nociceptive brain-stem neurones

    J. W. Hu;B. J. Sessle;P. Raboisson;R. Dallel

  • Sex-related differences in human pain and rat afferent discharge evoked by injection of glutamate into the masseter muscle.

    Brian E. Cairns;James W. Hu;Lars Arendt-Nielsen;Barry J. Sessle

  • Response properties of nociceptive and non-nociceptive neurons in the rat's trigeminal subnucleus caudalis (medullary dorsal horn) related to cutaneous and deep craniofacial afferent stimulation and modulation by diffuse noxious inhibitory controls.

    James W. Hu

  • Glutamate-evoked pain and mechanical allodynia in the human masseter muscle.

    Peter Svensson;Peter Svensson;Peter Svensson;Brian E Cairns;Kelun Wang;James W Hu

  • Trigeminal subnucleus caudalis: beyond homologies with the spinal dorsal horn.

    David A Bereiter;Harumitsu Hirata;James W Hu

  • Effects of inflammatory irritant application to the rat temporomandibular joint on jaw and neck muscle activity

    X.-M. Yu;B. J. Sessle;H. Vernon;J. W. Hu

  • Evidence That Excitatory Amino Acid Receptors within the Temporomandibular Joint Region Are Involved in the Reflex Activation of the Jaw Muscles

    Brian E. Cairns;Barry J. Sessle;James W. Hu

  • Responses of neurons in feline trigeminal subnucleus caudalis (medullary dorsal horn) to cutaneous, intraoral, and muscle afferent stimuli.

    N. Amano;J. W. Hu;B. J. Sessle

  • Encoding of Corneal Input in Two Distinct Regions of the Spinal Trigeminal Nucleus in the Rat: Cutaneous Receptive Field Properties, Responses to Thermal and Chemical Stimulation, Modulation by Diffuse Noxious Inhibitory Controls, and Projections to the Parabrachial Area

    I. D. Meng;J. W. Hu;A. P. Benetti;D. A. Bereiter

  • Distribution of fos‐like immunoreactivity in the caudal brainstem of the rat following noxious chemical stimulation of the temporomandibular joint

    Charles B. Hathaway;James W. Hu;David A. Bereiter

  • Raphe-induced suppression of the jaw-opening reflex and single neurons in trigeminal subnucleus oralis, and influence of naloxone and subnucleus caudalis

    Barry J. Sessle;James W. Hu

  • Effects of substance P on nociceptive and non-nociceptive trigeminal brain stem neurons

    James L. Henry;James L. Henry;Barry J. Sessle;Barry J. Sessle;Gregory E. Lucier;Gregory E. Lucier;James W. Hu;James W. Hu

  • Involvement of glia in central sensitization in trigeminal subnucleus caudalis (medullary dorsal horn).

    Y.F. Xie;S. Zhang;C.Y. Chiang;J.W. Hu

  • Mechanisms of pain arising from articular tissues.

    Barry J. Sessle;James W. Hu

  • Astroglial Glutamate–Glutamine Shuttle Is Involved in Central Sensitization of Nociceptive Neurons in Rat Medullary Dorsal Horn

    Chen-Yu Chiang;Jing Wang;Yu-Feng Xie;Sun Zhang

  • SEX-RELATED DIFFERENCES IN NMDA-EVOKED RAT MASSETER MUSCLE AFFERENT DISCHARGE RESULT FROM ESTROGEN-MEDIATED MODULATION OF PERIPHERAL NMDA RECEPTOR ACTIVITY

    Xu-Dong Dong;Mandeep K. Mann;Ujendra Kumar;Peter Svensson

  • NMDA Receptor Mechanisms Contribute to Neuroplasticity Induced in Caudalis Nociceptive Neurons by Tooth Pulp Stimulation

    Chen Yu Chiang;Soo Joung Park;Chun L. Kwan;James W. Hu

Frequent Co-Authors

Barry J. Sessle
Barry J. Sessle University of Toronto
Jonathan O. Dostrovsky
Jonathan O. Dostrovsky University of Toronto
Brian E. Cairns
Brian E. Cairns University of British Columbia
David A. Bereiter
David A. Bereiter University of Minnesota
Koichi Iwata
Koichi Iwata Nihon University
Lars Arendt-Nielsen
Lars Arendt-Nielsen Aalborg University
Ujendra Kumar
Ujendra Kumar University of British Columbia
Kelun Wang
Kelun Wang Aalborg University
Sung-Tsang Hsieh
Sung-Tsang Hsieh National Taiwan University
Messoud Ashina
Messoud Ashina University of Copenhagen

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing James W. Hu