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Olivier Lefebvre

Olivier Lefebvre

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
8740
World Ranking
14666
National Ranking
569

Overview

Olivier Lefebvre is affiliated with the University of Strasbourg in France. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Oncology, Molecular Biology, and Immunology. Lefebvre's work also spans subfields such as Cancer Research and Biomaterials.

The main topics of their research include:

  • Inflammatory Biomarkers in Disease Prognosis
  • Nanoparticle-Based Drug Delivery
  • Extracellular Vesicles in Disease
  • MicroRNA in Disease Regulation
  • Cell Adhesion Molecules Research
  • Platelet Disorders and Treatments
  • Angiogenesis and VEGF in Cancer

Lefebvre has published extensively, with notable recent papers including:

  • "Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes," 2021, eLife
  • "Platelets favor the outgrowth of established metastases," 2024, Nature Communications
  • "Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells," 2021, Scientific Reports
  • "Fluorescent nanocarriers targeting VCAM-1 for early detection of senescent endothelial cells," 2021, Nanomedicine Nanotechnology Biology and Medicine
  • "Intrauterine Pressures Adjusted by Reichert's Membrane Are Crucial for Early Mouse Morphogenesis," 2020, Cell Reports

Lefebvre has collaborated frequently with other researchers in their field. Frequent co-authors include:

  • Jacky G. Goetz
  • Vincent Mittelheisser
  • Annabel Larnicol
  • Raphaël Carapito
  • Vincent Hyenne

Their research has been published in several prominent scientific journals and venues, with the highest number of papers appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Scientific Reports
  • iScience
  • Advanced Science

Best Publications

  • Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein.

    Olivier Lefebvre;Marie-Pierre Chenard;Régis Masson;José Linares

  • In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy.

    Régis Masson;Olivier Lefebvre;Agnès Noël;Mostapha El Fahime

  • Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide.

    Catherine Tomasetto;Sherif M. Karam;Stephane Ribieras;Régis Masson

  • Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells

    Gautier Follain;Naël Osmani;Ana Sofia Azevedo;Guillaume Allio

  • The breast cancer-associated stromelysin-3 gene is expressed during mouse mammary gland apoptosis.

    O Lefebvre;C Wolf;J M Limacher;P Hutin

  • RAL-1 controls multivesicular body biogenesis and exosome secretion.

    Vincent Hyenne;Ahmet Apaydin;David Rodriguez;Coralie Spiegelhalter

  • pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins ☆ ☆☆ ★

    Catherine Tomasetto;Régis Masson;José–Luis Linares;Corinne Wendling

  • Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo

    Vincent Hyenne;Shima Ghoroghi;Shima Ghoroghi;Mayeul Collot;Joanna Bons

  • Inhibition of laminin alpha 1-chain expression leads to alteration of basement membrane assembly and cell differentiation.

    A De Arcangelis;P Neuville;R Boukamel;O Lefebvre

  • Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal

    Shantisree Sandeepani Rayagiri;Shantisree Sandeepani Rayagiri;Daniele Ranaldi;Alexander Raven;Alexander Raven;Nur Izzah Farhana Mohamad Azhar

  • The 28-kDa N-terminal domain of mouse stromelysin-3 has the general properties of a weak metalloproteinase

    G Murphy;J P Segain;M O'Shea;M Cockett

  • Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond–like features

    Raphael Carapito;Martina Konantz;Catherine Paillard;Zhichao Miao

  • Developmental expression of mouse stromelysin-3 mRNA.

    O. Lefebvre;C. Regnier;M.P. Chenard;C. Wendling

  • The mouse one P-domain (pS2) and two P-domain (mSP) genes exhibit distinct patterns of expression.

    O Lefebvre;C Wolf;M Kédinger;MP Chenard

  • Stromelysin-3 expression promotes tumor take in nude mice

    Agnès Noël;O. Lefebvre;Erik Maquoi;L. Vanhoorde

  • Developmental Expression and Cellular Origin of the Laminin α2, α4, and α5 Chains in the Intestine

    Olivier Lefebvre;Lydia Sorokin;Michèle Kedinger;Patricia Simon-Assmann

  • The Laminins: Role in Intestinal Morphogenesis and Differentiation

    P. Simon‐Assmann;O. Lefebvre;A. Bellissent‐Waydelich;J. Olsen

  • Tenascin-C Downregulates Wnt Inhibitor Dickkopf-1, Promoting Tumorigenesis in a Neuroendocrine Tumor Model

    Falk Saupe;Anja Schwenzer;Yundan Jia;Isabelle Gasser

  • A Novel Subunit of Yeast RNA Polymerase III Interacts with the TFIIB-Related Domain of TFIIIB70

    Maria-Laura Ferri;Gérald Peyroche;Magali Siaut;Olivier Lefebvre

  • Tenascin-C Promotes Tumor Cell Migration and Metastasis through Integrin α9β1–Mediated YAP Inhibition

    Zhen Sun;Anja Schwenzer;Tristan Rupp;Devadarssen Murdamoothoo

Frequent Co-Authors

Patricia Simon-Assmann
Patricia Simon-Assmann Grenoble Alpes University
Michèle Kedinger
Michèle Kedinger University of Strasbourg
André Sentenac
André Sentenac French Alternative Energies and Atomic Energy Commission (CEA)
Marie-Christine Rio
Marie-Christine Rio Grenoble Alpes University
Paul Timpson
Paul Timpson Garvan Institute of Medical Research
Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Lydia Sorokin
Lydia Sorokin University of Münster
Catherine Tomasetto
Catherine Tomasetto Institute of Genetics and Molecular and Cellular Biology
Andrey S. Klymchenko
Andrey S. Klymchenko University of Strasbourg
Sylvie Robine
Sylvie Robine Institute Curie

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