World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
65
Citations
15886
World Ranking
1666
National Ranking
131

Overview

Christoph W. Müller is affiliated with the European Bioinformatics Institute in the United Kingdom. Their research primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with a substantial concentration in Molecular Biology. The work also spans into related subfields such as Materials Chemistry, Structural Biology, Epidemiology, and Genetics.

The core topics of their research encompass RNA Research and Splicing, RNA and protein synthesis mechanisms, and RNA modifications and cancer. Additional areas include Genomics and Chromatin Dynamics, Advanced Electron Microscopy Techniques and Applications, Nuclear Structure and Function, and Virus-based gene therapy research.

Christoph W. Müller has contributed extensively to scientific literature, with recent papers including:

  • In-cell architecture of the nuclear pore and snapshots of its turnover (2020, Nature)
  • Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases (2022, Nature Reviews Molecular Cell Biology)
  • Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states (2021, Nature Structural & Molecular Biology)
  • Molecular mechanisms of stress-induced reactivation in mumps virus condensates (2023, Cell)
  • Structural basis for RNA polymerase III transcription repression by Maf1 (2020, Nature Structural & Molecular Biology)

Their frequent coauthors include Julia Mahamid, Mathias Girbig, Herman K.H. Fung, Florence Baudin, and Agata D. Misiaszek.

Publication venues where Müller has regularly appeared include bioRxiv (Cold Spring Harbor Laboratory), Nature Structural & Molecular Biology, Science Advances, Nature, and Nucleic Acids Research.

Best Publications

  • Three-dimensional structure of the Stat3β homodimer bound to DNA

    Stefan Becker;Bernd Groner;Christoph W. Müller

  • Structure of importin-beta bound to the IBB domain of importin-alpha.

    Gino Cingolani;Carlo Petosa;Karsten Weis;Christoph W. Müller

  • Structure of the NF-kappa B p50 homodimer bound to DNA.

    Christoph W. Müller;Félix A. Rey;Mikiko Sodeoka;Mikiko Sodeoka;Gregory L. Verdine

  • WD40 proteins propel cellular networks

    Christian U. Stirnimann;Evangelia Petsalaki;Robert B. Russell;Christoph W. Müller

  • Comparison of ARM and HEAT protein repeats.

    Miguel A Andrade;Carlo Petosa;Sean I O’Donoghue;Christoph W Müller

  • Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap5A refined at 1.9 A resolution. A model for a catalytic transition state.

    Christoph W. Müller;Georg E. Schulz

  • Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

    Jeanne Morinière;Sophie Rousseaux;Ulrich Steuerwald;Montserrat Soler-López

  • Adenylate kinase motions during catalysis: an energetic counterweight balancing substrate binding

    C. W. Müller;G. J. Schlauderer;Jochen Reinstein;Georg E. Schulz

  • Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression.

    Reinhard Kalb;Sebastian Latwiel;H Irem Baymaz;Pascal W T C Jansen

  • Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor.

    Christoph W. Müller;Bernhard G. Herrmann

  • Crystal Structure and Functional Analysis of a Nucleosome Recognition Module of the Remodeling Factor Iswi

    Tim Grüne;Jan Brzeski;Anton Eberharter;Cedric R Clapier

  • HDAC6–p97/VCP controlled polyubiquitin chain turnover

    Cyril Boyault;Benoit Gilquin;Yu Zhang;Vladimir Rybin

  • Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2)

    Hatice Akarsu;Hatice Akarsu;Wilhelm P. Burmeister;Wilhelm P. Burmeister;Carlo Petosa;Isabelle Petit

  • Karyopherin flexibility in nucleocytoplasmic transport.

    Elena Conti;Christoph W Müller;Murray Stewart

  • Induced-fit movements in adenylate kinases

    Georg E. Schulz;Christoph W. Müller;Kay Diederichs

  • Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis

    Luis Luna-Zurita;Christian U. Stirnimann;Sebastian Glatt;Bogac L. Kaynak

  • Pervasive Protein Thermal Stability Variation during the Cell Cycle.

    Isabelle Becher;Amparo Andrés-Pons;Natalie Romanov;Frank Stein

  • Crystal structure of the 14-subunit RNA polymerase I

    Carlos Fernández-Tornero;María Moreno-Morcillo;Umar J. Rashid;Nicholas M. I. Taylor

  • Structure of the human NF‐κB p52 homodimer‐DNA complex at 2.1 Å resolution

    Patrick Cramer;Christopher J. Larson;Christopher J. Larson;Gregory L. Verdine;Christoph W. Müller

  • Molecular structures of unbound and transcribing RNA polymerase III

    Niklas A. Hoffmann;Arjen J. Jakobi;María Moreno-Morcillo;Sebastian Glatt

Frequent Co-Authors

Vladimir Rybin
Vladimir Rybin European Molecular Biology Laboratory
Martin Beck
Martin Beck TU Dresden
Bertrand Séraphin
Bertrand Séraphin Institute of Genetics and Molecular and Cellular Biology
Anne-Claude Gavin
Anne-Claude Gavin University of Geneva
Peer Bork
Peer Bork European Molecular Biology Laboratory
Rob W.H. Ruigrok
Rob W.H. Ruigrok Grenoble Alpes University
Georg E. Schulz
Georg E. Schulz University of Freiburg
Stephen C. Harrison
Stephen C. Harrison Harvard University
Guy Schoehn
Guy Schoehn Grenoble Alpes University
Robert B. Russell
Robert B. Russell Heidelberg University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring molecular biology opens the door to a range of interdisciplinary opportunities. Many students with a background in biology pursue alternative paths with related online degrees, expanding their career options beyond traditional research roles.

For instance, knowledge of biology and genetics is valuable if you’re considering a future in education or healthcare. If you’re interested in working with communication disorders, learning about what is an slp in education demonstrates how scientific training can support a transition to fields like speech-language pathology.

Tech-savvy students might consider exploring architect online degree programs, which use biology-inspired design and sustainability principles. Analytical thinkers may benefit from online mathematics degrees to enhance their quantitative and data analysis skills, increasingly vital in biomolecular research.

Additionally, those interested in visual communication should look into online graphic design programs—ideal for bringing complex biological concepts to life through infographics and interactive media. With so many online pathways, students can tailor their education to meet evolving career goals in science and beyond.

Best Scientists Citing Christoph W. Müller

Trending Scientists