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Anne-Claude Gavin

Anne-Claude Gavin

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
23380
World Ranking
15891
National Ranking
294

Overview

Anne-Claude Gavin is affiliated with the University of Geneva in Switzerland. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with notable contributions in several subfields including Molecular Biology, Immunology, Surgery, Cell Biology, and Physiology.

The scientist's work focuses on important biological processes and mechanisms related to lipid and cholesterol metabolism, immune cell function in cancer, cellular stress responses, and mitochondrial pathology. Their main areas of study include:

  • Lipid Membrane Structure and Behavior
  • Cholesterol and Lipid Metabolism
  • Immune cells in cancer
  • Sphingolipid Metabolism and Signaling
  • Mitochondrial Function and Pathology
  • Single-cell and spatial transcriptomics
  • Endoplasmic Reticulum Stress and Disease

Anne-Claude Gavin has contributed to multiple recent publications covering these topics. Key papers include:

  • "APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes" (2021) published in Stem Cell Reports
  • "Isoform- and cell-state-specific lipidation of ApoE in astrocytes" (2022) published in Cell Reports
  • "Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes" (2020) published in EBioMedicine
  • "Dynamic Buffering of Extracellular Chemokine by a Dedicated Scavenger Pathway Enables Robust Adaptation during Directed Tissue Migration" (2020) published in Developmental Cell
  • "Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats" (2020) published in PLoS ONE

Their frequent coauthors include colleagues with whom they have published extensively, among them:

  • Laura Poisa-Beiro
  • Anthony D. Ho
  • Volker Eckstein
  • Simon Raffel
  • Karina Lindner

The scientist publishes predominantly in venues that focus on molecular and cellular biology. The most common publication outlets for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • International Journal of Molecular Sciences
  • Stem Cell Reports
  • PLoS ONE

Best Publications

  • Functional organization of the yeast proteome by systematic analysis of protein complexes

    Anne-Claude Gavin;Markus Bösche;Roland Krause;Paola Grandi

  • Proteome survey reveals modularity of the yeast cell machinery

    Anne-Claude Gavin;Patrick Aloy;Paola Grandi;Roland Krause

  • A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

    Tewis Bouwmeester;Angela Bauch;Heinz Ruffner;Pierre-Olivier Angrand

  • Drug Target Identification Using Side-Effect Similarity

    Monica Campillos;Michael Kuhn;Anne-Claude Gavin;Lars Juhl Jensen;Lars Juhl Jensen

  • Visualization of omics data for systems biology

    Nils Gehlenborg;Seán I O'Donoghue;Nitin S Baliga;Alexander Goesmann

  • 90S Pre-Ribosomes Include the 35S Pre-rRNA, the U3 snoRNP, and 40S Subunit Processing Factors but Predominantly Lack 60S Synthesis Factors

    Paola Grandi;Vladimir Rybin;Jochen Baßler;Elisabeth Petfalski

  • Proteome Organization in a Genome-Reduced Bacterium

    Sebastian Kühner;Vera van Noort;Matthew J. Betts;Alejandra Leo-Macias

  • Transcriptome Complexity in a Genome-Reduced Bacterium

    Marc Güell;Vera Van Noort;Eva Yus;Wei Hua Chen

  • Structure-Based Assembly of Protein Complexes in Yeast

    Patrick Aloy;Bettina Böttcher;Hugo Ceulemans;Christina Leutwein

  • A link between MAP kinase and p34cdc2/cyclin B during oocyte maturation: p90rsk phosphorylates and inactivates the p34cdc2 inhibitory kinase Myt1

    Amparo Palmer;Anne‐Claude Gavin;Angel R. Nebreda

  • Impact of Genome Reduction on Bacterial Metabolism and Its Regulation

    Eva Yus;Tobias Maier;Konstantinos Michalodimitrakis;Vera van Noort

  • Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

    Kenji Maeda;Kanchan Anand;Kanchan Anand;Antonella Chiapparino;Arun Kumar

  • Quantification of mRNA and protein and integration with protein turnover in a bacterium.

    Tobias Maier;Alexander Schmidt;Marc Güell;Sebastian Kühner

  • The minimum information required for reporting a molecular interaction experiment (MIMIx)

    Sandra Orchard;Lukasz Salwinski;Samuel Kerrien;Luisa Montecchi-Palazzi

  • Deciphering a global network of functionally associated post‐translational modifications

    Pablo Minguez;Luca Parca;Francesca Diella;Daniel R Mende

  • Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations

    Andrea Pellagatti;Richard N. Armstrong;Violetta Steeples;Eshita Sharma

  • A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses

    Marielle S. Köberlin;Berend Snijder;Leonhard X. Heinz;Christoph L. Baumann

  • Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium

    Vera van Noort;Jan Seebacher;Samuel Bader;Shabaz Mohammed

  • Modules, networks and systems medicine for understanding disease and aiding diagnosis

    Mika Gustafsson;Colm E. Nestor;Huan Zhang;Albert-Laszlo Barabasi

  • A MAP kinase docking site is required for phosphorylation and activation of p90rsk/MAPKAP kinase-1

    Anne-Claude Gavin;Angel R. Nebreda

Frequent Co-Authors

Peer Bork
Peer Bork European Molecular Biology Laboratory
Luis Serrano
Luis Serrano Centre for Genomic Regulation
Giulio Superti-Furga
Giulio Superti-Furga Medical University of Vienna
Robert B. Russell
Robert B. Russell Heidelberg University
Vladimir Rybin
Vladimir Rybin European Molecular Biology Laboratory
Anthony D. Ho
Anthony D. Ho University Hospital Heidelberg
Christoph W. Müller
Christoph W. Müller European Bioinformatics Institute
Patrick Aloy
Patrick Aloy Institució Catalana de Recerca i Estudis Avançats
Bernhard Kuster
Bernhard Kuster Technical University of Munich
Jan Ellenberg
Jan Ellenberg European Bioinformatics Institute

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