Bertrand Séraphin

Research.com Recognitions

• 2024 - Research.com Genetics in France Leader Award
• 2024 - Research.com Genetics and Molecular Biology in France Leader Award
• 1969 - Fellow of American Physical Society (APS)
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• Functional organization of the yeast proteome by systematic analysis of protein complexes

  Anne-Claude Gavin;Markus Bösche;Roland Krause;Paola Grandi

  6097
  Citations

• A generic protein purification method for protein complex characterization and proteome exploration.

  Guillaume Rigaut;Anna Shevchenko;Berthold Rutz;Matthias Wilm

  3600
  Citations

• The tandem affinity purification (TAP) method: a general procedure of protein complex purification.

  Oscar Puig;Friederike Caspary;Guillaume Rigaut;Berthold Rutz

  2389
  Citations

• Cryptic Pol II Transcripts Are Degraded by a Nuclear Quality Control Pathway Involving a New Poly(A) Polymerase

  Françoise Wyers;Mathieu Rougemaille;Gwenaël Badis;Jean-Claude Rousselle

  986
  Citations

• Cytoplasmic foci are sites of mRNA decay in human cells

  Nicolas Cougot;Sylvie Babajko;Bertrand Séraphin

  895
  Citations

• Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion.

  Attila Becskei;Bertrand Séraphin;Luis Serrano

  882
  Citations

• Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures

  Erwin van Dijk;Nicolas Cougot;Sylke Meyer;Sylvie Babajko

  670
  Citations

• A Sm-like protein complex that participates in mRNA degradation.

  Emmanuelle Bouveret;Guillaume Rigaut;Anna Shevchenko;Matthias Wilm

  542
  Citations

• Structure of the Exon Junction Core Complex with a Trapped DEAD-Box ATPase Bound to RNA

  Christian B. F. Andersen;Lionel Ballut;Lionel Ballut;Jesper S. Johansen;Hala Chamieh

  509
  Citations

• A single subunit, Dis3, is essentially responsible for yeast exosome core activity.

  Andrzej Dziembowski;Esben Lorentzen;Elena Conti;Bertrand Séraphin

  493
  Citations

• REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.

  Françoise Stutz;Angela Bachi;Tobias Doerks;Isabelle C. Braun

  484
  Citations

• Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing

  Bertrand Seraphin;Michael Rosbash

  474
  Citations

• A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5' cleavage site.

  B. Séraphin;L. Kretzner;M. Rosbash

  453
  Citations

• Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs.

  B Séraphin

  397
  Citations

• Endonucleolytic RNA cleavage by a eukaryotic exosome

  Alice Lebreton;Alice Lebreton;Rafal Tomecki;Rafal Tomecki;Andrzej Dziembowski;Andrzej Dziembowski;Bertrand Séraphin;Bertrand Séraphin

  378
  Citations

• The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity.

  Lionel Ballut;Brice Marchadier;Aurélie Baguet;Catherine Tomasetto

  377
  Citations

• Role of U6 snRNA in 5' splice site selection

  Stefanie Kandels-Lewis;Bertrand Séraphin

  353
  Citations

• The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies.

  Theophany Eystathioy;Andrew Jakymiw;Edward K.L. Chan;Bertrand Séraphin

  346
  Citations

• Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p.

  Christel Schmitt;Cayetano von Kobbe;Angela Bachi;Nelly Panté

  340
  Citations

• The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing.

  Patrik Förch;Oscar Puig;Nancy Kedersha;Concepción Martínez

  337
  Citations